Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385779507> ?p ?o ?g. }
- W4385779507 endingPage "145418" @default.
- W4385779507 startingPage "145418" @default.
- W4385779507 abstract "DNA molecular probes have been increasingly used for biological imaging and tumor theranostics. In particular, live-cell imaging of low abundance microRNA (miRNA) with high accuracy and efficiency was extremely important for understanding functions and dynamics of miRNA. Herein, an easy-to-obtain DNA-nucleated spherical nucleic acid (DSNA) was constructed by one pair of hairpin probes “sticked” on self-assembled three-dimensional (3D) urchin-like DNA nanostructures (UDNs) to realize sensitive imaging of tumor-related miRNA in living cells. UDNs were prepared through four short single-stranded DNA by a simple “one-pot” annealing process that took only a few minutes. Moreover, sticking the reactants of hairpin probes on the UDNs not only sped up the reaction kinetic rate, but also improved the sensitivity and efficiency of miRNA-triggered hairpin cascade circuits. Compared with traditional AuNP-based spherical nucleic acid, the DSNA possessed superb biocompatibility and stability, excellent cell internalization capability and accessibility, which endowed them tremendous advantages for the monitoring of miRNA in living cells. Therefore, our developed strategy exhibited great potential in sensitive imaging of intracellular miRNA, offering a new avenue for early tumor diagnosis and related biomedical research." @default.
- W4385779507 created "2023-08-13" @default.
- W4385779507 creator A5023962923 @default.
- W4385779507 creator A5044881716 @default.
- W4385779507 creator A5057370040 @default.
- W4385779507 creator A5057739867 @default.
- W4385779507 creator A5059107046 @default.
- W4385779507 date "2023-10-01" @default.
- W4385779507 modified "2023-10-14" @default.
- W4385779507 title "Hairpin cascade circuits on programmable DNA-nucleated spherical nucleic acid for intracellular targeted microRNA imaging" @default.
- W4385779507 cites W1974770318 @default.
- W4385779507 cites W2067557961 @default.
- W4385779507 cites W2159888101 @default.
- W4385779507 cites W2170943648 @default.
- W4385779507 cites W2602614828 @default.
- W4385779507 cites W2724802806 @default.
- W4385779507 cites W2740337666 @default.
- W4385779507 cites W2809776129 @default.
- W4385779507 cites W2886514991 @default.
- W4385779507 cites W2888486896 @default.
- W4385779507 cites W2948902514 @default.
- W4385779507 cites W2982780080 @default.
- W4385779507 cites W3094159415 @default.
- W4385779507 cites W3096839196 @default.
- W4385779507 cites W3119255431 @default.
- W4385779507 cites W3119702669 @default.
- W4385779507 cites W3120308621 @default.
- W4385779507 cites W3126854845 @default.
- W4385779507 cites W3139675969 @default.
- W4385779507 cites W3168572828 @default.
- W4385779507 cites W3171835979 @default.
- W4385779507 cites W3172548493 @default.
- W4385779507 cites W3172942648 @default.
- W4385779507 cites W3210726397 @default.
- W4385779507 cites W3215634900 @default.
- W4385779507 cites W4206796839 @default.
- W4385779507 cites W4207077956 @default.
- W4385779507 cites W4210514772 @default.
- W4385779507 cites W4210575504 @default.
- W4385779507 cites W4213137291 @default.
- W4385779507 cites W4214592899 @default.
- W4385779507 cites W4214839796 @default.
- W4385779507 cites W4220783349 @default.
- W4385779507 cites W4221057758 @default.
- W4385779507 cites W4221120705 @default.
- W4385779507 cites W4224946952 @default.
- W4385779507 cites W4225405164 @default.
- W4385779507 cites W4284690482 @default.
- W4385779507 cites W4291109317 @default.
- W4385779507 cites W4293124980 @default.
- W4385779507 cites W4307482747 @default.
- W4385779507 cites W4312112895 @default.
- W4385779507 doi "https://doi.org/10.1016/j.cej.2023.145418" @default.
- W4385779507 hasPublicationYear "2023" @default.
- W4385779507 type Work @default.
- W4385779507 citedByCount "0" @default.
- W4385779507 crossrefType "journal-article" @default.
- W4385779507 hasAuthorship W4385779507A5023962923 @default.
- W4385779507 hasAuthorship W4385779507A5044881716 @default.
- W4385779507 hasAuthorship W4385779507A5057370040 @default.
- W4385779507 hasAuthorship W4385779507A5057739867 @default.
- W4385779507 hasAuthorship W4385779507A5059107046 @default.
- W4385779507 hasConcept C104317684 @default.
- W4385779507 hasConcept C12554922 @default.
- W4385779507 hasConcept C139770010 @default.
- W4385779507 hasConcept C145059251 @default.
- W4385779507 hasConcept C1491633281 @default.
- W4385779507 hasConcept C171250308 @default.
- W4385779507 hasConcept C178790620 @default.
- W4385779507 hasConcept C185592680 @default.
- W4385779507 hasConcept C192562407 @default.
- W4385779507 hasConcept C24107716 @default.
- W4385779507 hasConcept C2777230088 @default.
- W4385779507 hasConcept C552990157 @default.
- W4385779507 hasConcept C55493867 @default.
- W4385779507 hasConcept C79879829 @default.
- W4385779507 hasConcept C86803240 @default.
- W4385779507 hasConcept C95444343 @default.
- W4385779507 hasConceptScore W4385779507C104317684 @default.
- W4385779507 hasConceptScore W4385779507C12554922 @default.
- W4385779507 hasConceptScore W4385779507C139770010 @default.
- W4385779507 hasConceptScore W4385779507C145059251 @default.
- W4385779507 hasConceptScore W4385779507C1491633281 @default.
- W4385779507 hasConceptScore W4385779507C171250308 @default.
- W4385779507 hasConceptScore W4385779507C178790620 @default.
- W4385779507 hasConceptScore W4385779507C185592680 @default.
- W4385779507 hasConceptScore W4385779507C192562407 @default.
- W4385779507 hasConceptScore W4385779507C24107716 @default.
- W4385779507 hasConceptScore W4385779507C2777230088 @default.
- W4385779507 hasConceptScore W4385779507C552990157 @default.
- W4385779507 hasConceptScore W4385779507C55493867 @default.
- W4385779507 hasConceptScore W4385779507C79879829 @default.
- W4385779507 hasConceptScore W4385779507C86803240 @default.
- W4385779507 hasConceptScore W4385779507C95444343 @default.
- W4385779507 hasLocation W43857795071 @default.
- W4385779507 hasOpenAccess W4385779507 @default.
- W4385779507 hasPrimaryLocation W43857795071 @default.
- W4385779507 hasRelatedWork W1585685362 @default.