FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385780388> ?p ?o ?g. }

• W4385780388 abstract "Within the cell, the trace element molybdenum (Mo) is only biologically active when complexed either within the nitrogenase-specific FeMo cofactor or within the molybdenum cofactor (Moco). Moco consists of an organic part, called molybdopterin (MPT) and an inorganic part, that is, the Mo-center. The enzyme which catalyzes the Mo-center formation is the molybdenum insertase (Mo-insertase). Mo-insertases consist of two functional domains called G- and E-domain. The G-domain catalyzes the formation of adenylated MPT (MPT-AMP), which is the substrate for the E-domain, that catalyzes the actual molybdate insertion reaction. Though the functions of E- and G-domain have been elucidated to great structural and mechanistic detail, their combined function is poorly characterized. In this work, we describe a structural model of the eukaryotic Mo-insertase Cnx1 complex that was generated based on cross-linking mass spectrometry combined with computational modeling. We revealed Cnx1 to form an asymmetric hexameric complex which allows the E- and G-domain active sites to align in a catalytic productive orientation toward each other." @default.
• W4385780388 created "2023-08-13" @default.
• W4385780388 creator A5008682765 @default.
• W4385780388 creator A5018872152 @default.
• W4385780388 creator A5035026621 @default.
• W4385780388 creator A5036279324 @default.
• W4385780388 creator A5076952708 @default.
• W4385780388 creator A5084158849 @default.
• W4385780388 date "2023-08-28" @default.
• W4385780388 modified "2023-10-17" @default.
• W4385780388 title "The structural principles underlying molybdenum insertase complex assembly" @default.
• W4385780388 cites W1827541519 @default.
• W4385780388 cites W1978381941 @default.
• W4385780388 cites W1987064733 @default.
• W4385780388 cites W1995920378 @default.
• W4385780388 cites W2002473282 @default.
• W4385780388 cites W2012026218 @default.
• W4385780388 cites W2012104865 @default.
• W4385780388 cites W2018456910 @default.
• W4385780388 cites W2018523756 @default.
• W4385780388 cites W2026707096 @default.
• W4385780388 cites W2033315152 @default.
• W4385780388 cites W2035503835 @default.
• W4385780388 cites W2046869450 @default.
• W4385780388 cites W2060473313 @default.
• W4385780388 cites W2062952123 @default.
• W4385780388 cites W2063024918 @default.
• W4385780388 cites W2070720026 @default.
• W4385780388 cites W2073740137 @default.
• W4385780388 cites W2081825687 @default.
• W4385780388 cites W2090183113 @default.
• W4385780388 cites W2090311503 @default.
• W4385780388 cites W2100008681 @default.
• W4385780388 cites W2102461176 @default.
• W4385780388 cites W2102987827 @default.
• W4385780388 cites W2115167726 @default.
• W4385780388 cites W2116446688 @default.
• W4385780388 cites W2119073376 @default.
• W4385780388 cites W2124026197 @default.
• W4385780388 cites W2129779698 @default.
• W4385780388 cites W2132629607 @default.
• W4385780388 cites W2148900757 @default.
• W4385780388 cites W2150284877 @default.
• W4385780388 cites W2153983456 @default.
• W4385780388 cites W2154019529 @default.
• W4385780388 cites W2166290675 @default.
• W4385780388 cites W2333303357 @default.
• W4385780388 cites W2376573086 @default.
• W4385780388 cites W2398577603 @default.
• W4385780388 cites W2547950325 @default.
• W4385780388 cites W2801560783 @default.
• W4385780388 cites W2811279208 @default.
• W4385780388 cites W2898649585 @default.
• W4385780388 cites W2997060324 @default.
• W4385780388 cites W3000695858 @default.
• W4385780388 cites W3015967331 @default.
• W4385780388 cites W3035953143 @default.
• W4385780388 cites W3082094306 @default.
• W4385780388 cites W3094230501 @default.
• W4385780388 cites W3173585299 @default.
• W4385780388 cites W38635977 @default.
• W4385780388 cites W4292860060 @default.
• W4385780388 cites W4303959091 @default.
• W4385780388 cites W4385780388 @default.
• W4385780388 doi "https://doi.org/10.1002/pro.4753" @default.
• W4385780388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37572332" @default.
• W4385780388 hasPublicationYear "2023" @default.
• W4385780388 type Work @default.
• W4385780388 citedByCount "1" @default.
• W4385780388 countsByYear W43857803882023 @default.
• W4385780388 crossrefType "journal-article" @default.
• W4385780388 hasAuthorship W4385780388A5008682765 @default.
• W4385780388 hasAuthorship W4385780388A5018872152 @default.
• W4385780388 hasAuthorship W4385780388A5035026621 @default.
• W4385780388 hasAuthorship W4385780388A5036279324 @default.
• W4385780388 hasAuthorship W4385780388A5076952708 @default.
• W4385780388 hasAuthorship W4385780388A5084158849 @default.
• W4385780388 hasBestOaLocation W43857803881 @default.
• W4385780388 hasConcept C134306372 @default.
• W4385780388 hasConcept C161790260 @default.
• W4385780388 hasConcept C179104552 @default.
• W4385780388 hasConcept C181199279 @default.
• W4385780388 hasConcept C185592680 @default.
• W4385780388 hasConcept C197957613 @default.
• W4385780388 hasConcept C2775981058 @default.
• W4385780388 hasConcept C2777757664 @default.
• W4385780388 hasConcept C33923547 @default.
• W4385780388 hasConcept C36503486 @default.
• W4385780388 hasConcept C41183919 @default.
• W4385780388 hasConcept C549387045 @default.
• W4385780388 hasConcept C55493867 @default.
• W4385780388 hasConcept C71240020 @default.
• W4385780388 hasConcept C8010536 @default.
• W4385780388 hasConceptScore W4385780388C134306372 @default.
• W4385780388 hasConceptScore W4385780388C161790260 @default.
• W4385780388 hasConceptScore W4385780388C179104552 @default.
• W4385780388 hasConceptScore W4385780388C181199279 @default.
• W4385780388 hasConceptScore W4385780388C185592680 @default.
• W4385780388 hasConceptScore W4385780388C197957613 @default.
• W4385780388 hasConceptScore W4385780388C2775981058 @default.

• next