Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385781357> ?p ?o ?g. }
- W4385781357 abstract "Abstract Zinc oxide nanorods have been extensively studied for the specific killing of breast cancer (BC) cells, and their killing mechanism and anticancer effects have been initially demonstrated. However, systematic studies at the single‐cell level are still necessary to explore cellular functions in detail. In this work, a hydrothermal method was used to synthesize zinc oxide nanorod arrays (ZnO NRs). Their effect on BC cells was demonstrated at single‐cell resolution for the first time through microfluidic chips and a single‐cell analysis platform. The inhibitory effects of ZnO NRs were observed. First, ZnO NRs suppressed cell proliferation and migration abilities. Moreover, Interferon‐γ, Tumor Necrosis Factor‐α, and Granzyme B in BC cells turned out to be antitumor instead of tumorigenic under ZnO NRs stimulation. Furthermore, ZnO NRs inhibition altered cellular functions and thus weakened intercellular and intercluster correlations. More importantly, MDA‐MB‐231 cells (strongly metastatic) showed much greater resistance to ZnO NRs than MCF‐7 cells (nonmetastatic). The experiments complemented the findings at the single‐cell level and provided a more comprehensive consideration of the potential risks and applications of ZnO NRs in breast cancer therapy, which is of great importance for biomedical research on nanomaterials." @default.
- W4385781357 created "2023-08-13" @default.
- W4385781357 creator A5003850660 @default.
- W4385781357 creator A5013115993 @default.
- W4385781357 creator A5013541187 @default.
- W4385781357 creator A5014446719 @default.
- W4385781357 creator A5025886039 @default.
- W4385781357 creator A5037419475 @default.
- W4385781357 creator A5055838753 @default.
- W4385781357 creator A5065933713 @default.
- W4385781357 creator A5067592292 @default.
- W4385781357 creator A5071773009 @default.
- W4385781357 creator A5073070877 @default.
- W4385781357 creator A5078361927 @default.
- W4385781357 date "2023-08-11" @default.
- W4385781357 modified "2023-10-17" @default.
- W4385781357 title "Inhibitory effect of zinc oxide nanorod arrays on breast cancer cells profiled through real‐time cytokines screening by a single‐cell microfluidic platform" @default.
- W4385781357 cites W1568341953 @default.
- W4385781357 cites W1968953482 @default.
- W4385781357 cites W1984429906 @default.
- W4385781357 cites W1989307501 @default.
- W4385781357 cites W1996796384 @default.
- W4385781357 cites W2020287946 @default.
- W4385781357 cites W2040745562 @default.
- W4385781357 cites W2050528848 @default.
- W4385781357 cites W2121475792 @default.
- W4385781357 cites W2136240540 @default.
- W4385781357 cites W2146141473 @default.
- W4385781357 cites W2417230840 @default.
- W4385781357 cites W2478782740 @default.
- W4385781357 cites W2554729989 @default.
- W4385781357 cites W2559942094 @default.
- W4385781357 cites W2580767461 @default.
- W4385781357 cites W2584514101 @default.
- W4385781357 cites W2766936240 @default.
- W4385781357 cites W2773063173 @default.
- W4385781357 cites W2802731336 @default.
- W4385781357 cites W2807199418 @default.
- W4385781357 cites W2885710299 @default.
- W4385781357 cites W2891350091 @default.
- W4385781357 cites W2903681795 @default.
- W4385781357 cites W2907169041 @default.
- W4385781357 cites W2971518007 @default.
- W4385781357 cites W2973633093 @default.
- W4385781357 cites W2979368427 @default.
- W4385781357 cites W2995814603 @default.
- W4385781357 cites W2999681746 @default.
- W4385781357 cites W3006533027 @default.
- W4385781357 cites W3011265460 @default.
- W4385781357 cites W3016460152 @default.
- W4385781357 cites W3046373263 @default.
- W4385781357 cites W3082455880 @default.
- W4385781357 cites W3082462777 @default.
- W4385781357 cites W3084232290 @default.
- W4385781357 cites W3125180129 @default.
- W4385781357 cites W3125954993 @default.
- W4385781357 cites W3128722081 @default.
- W4385781357 cites W3152081978 @default.
- W4385781357 cites W3166627873 @default.
- W4385781357 cites W3167756601 @default.
- W4385781357 cites W3175111077 @default.
- W4385781357 cites W3175283754 @default.
- W4385781357 cites W3189383967 @default.
- W4385781357 cites W3191029526 @default.
- W4385781357 cites W3195237310 @default.
- W4385781357 cites W4214546240 @default.
- W4385781357 cites W4214587579 @default.
- W4385781357 cites W4221038261 @default.
- W4385781357 cites W4223955424 @default.
- W4385781357 cites W4281290498 @default.
- W4385781357 cites W4288385076 @default.
- W4385781357 cites W4303628102 @default.
- W4385781357 cites W4303700150 @default.
- W4385781357 cites W4309613527 @default.
- W4385781357 cites W4317632890 @default.
- W4385781357 cites W4317722136 @default.
- W4385781357 doi "https://doi.org/10.1002/bmm2.12040" @default.
- W4385781357 hasPublicationYear "2023" @default.
- W4385781357 type Work @default.
- W4385781357 citedByCount "1" @default.
- W4385781357 crossrefType "journal-article" @default.
- W4385781357 hasAuthorship W4385781357A5003850660 @default.
- W4385781357 hasAuthorship W4385781357A5013115993 @default.
- W4385781357 hasAuthorship W4385781357A5013541187 @default.
- W4385781357 hasAuthorship W4385781357A5014446719 @default.
- W4385781357 hasAuthorship W4385781357A5025886039 @default.
- W4385781357 hasAuthorship W4385781357A5037419475 @default.
- W4385781357 hasAuthorship W4385781357A5055838753 @default.
- W4385781357 hasAuthorship W4385781357A5065933713 @default.
- W4385781357 hasAuthorship W4385781357A5067592292 @default.
- W4385781357 hasAuthorship W4385781357A5071773009 @default.
- W4385781357 hasAuthorship W4385781357A5073070877 @default.
- W4385781357 hasAuthorship W4385781357A5078361927 @default.
- W4385781357 hasBestOaLocation W43857813571 @default.
- W4385781357 hasConcept C121608353 @default.
- W4385781357 hasConcept C126201875 @default.
- W4385781357 hasConcept C126322002 @default.
- W4385781357 hasConcept C1491633281 @default.
- W4385781357 hasConcept C171250308 @default.
- W4385781357 hasConcept C185592680 @default.