Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385782500> ?p ?o ?g. }
- W4385782500 abstract "Abstract Background Studies have examined the effect of weight change on osteoporosis, but the results were controversial. Among them, few had looked at weight change over the life span. This study aimed to fill this gap and investigate the association between lifetime body mass index (BMI) trajectories and bone loss. Methods In this cross-sectional study, participants at age 50 and above were selected from the National Health and Nutrition Examination Survey (NHANES) 2005–2018. Dual-energy X-ray Absorptiometry was used to measure the bone mineral density at the femoral neck and lumbar spine. Standard BMI criteria were used, with < 25 kg/m 2 for normal, 25–29.9 kg/m 2 for overweight, and ≥ 30 kg/m 2 for obesity. The latent class trajectory model (LCTM) was used to identify BMI trajectories. Multinomial logistic regression models were fitted to evaluate the association between different BMI trajectories and osteoporosis or osteopenia. Results For the 9,706 eligible participants, we identified four BMI trajectories, including stable (n = 7,681, 70.14%), slight increase (n = 1253, 12.91%), increase to decrease (n = 195, 2.01%), and rapid increase (n = 577, 5.94%). Compared with individuals in the stable trajectory, individuals in the rapid increase trajectory had higher odds of osteoporosis (OR = 2.25, 95% CI 1.19–4.23) and osteopenia (OR = 1.49, 95% CI 1.02–2.17). This association was only found in the lumbar spine (OR = 2.11, 95% CI 1.06–4.2) but not in the femoral neck. In early-stage (age 25–10 years ago) weight change, staying an obesity and stable weight seemed to have protective effects on osteoporosis (OR = 0.26, 95% CI 0.08–0.77) and osteopenia (OR = 0.46, 95% CI 0.25–0.84). Meanwhile, keeping an early-stage stable and overweight was related to lower odds of osteopenia (OR = 0.53, 95% CI 0.34–0.83). No statistically significant association between recent (10 years ago to baseline) weight change and osteoporosis was found. Conclusions Rapid and excess weight gain during adulthood is associated with a higher risk of osteoporosis. But this association varies by skeletal sites. Maintaining stable overweight and obesity at an early stage may have potentially beneficial effects on bone health." @default.
- W4385782500 created "2023-08-13" @default.
- W4385782500 creator A5023909153 @default.
- W4385782500 creator A5033323312 @default.
- W4385782500 creator A5033398105 @default.
- W4385782500 creator A5041523906 @default.
- W4385782500 creator A5041528294 @default.
- W4385782500 creator A5056094455 @default.
- W4385782500 creator A5062895804 @default.
- W4385782500 creator A5063128754 @default.
- W4385782500 creator A5066832333 @default.
- W4385782500 creator A5087279801 @default.
- W4385782500 date "2023-08-12" @default.
- W4385782500 modified "2023-10-11" @default.
- W4385782500 title "BMI trajectory of rapid and excessive weight gain during adulthood is associated with bone loss: a cross-sectional study from NHANES 2005–2018" @default.
- W4385782500 cites W1516495130 @default.
- W4385782500 cites W1964320725 @default.
- W4385782500 cites W1975081085 @default.
- W4385782500 cites W1979344569 @default.
- W4385782500 cites W1987627175 @default.
- W4385782500 cites W1999172425 @default.
- W4385782500 cites W2001013535 @default.
- W4385782500 cites W2003298815 @default.
- W4385782500 cites W2062009847 @default.
- W4385782500 cites W2075453955 @default.
- W4385782500 cites W2079250246 @default.
- W4385782500 cites W2088940658 @default.
- W4385782500 cites W2088948024 @default.
- W4385782500 cites W2107789045 @default.
- W4385782500 cites W2121758725 @default.
- W4385782500 cites W2126785421 @default.
- W4385782500 cites W2127398977 @default.
- W4385782500 cites W2132572939 @default.
- W4385782500 cites W2135312989 @default.
- W4385782500 cites W2342525617 @default.
- W4385782500 cites W2402991504 @default.
- W4385782500 cites W2503591039 @default.
- W4385782500 cites W2553392082 @default.
- W4385782500 cites W2735301415 @default.
- W4385782500 cites W2777746260 @default.
- W4385782500 cites W2792401749 @default.
- W4385782500 cites W2794722104 @default.
- W4385782500 cites W2805733706 @default.
- W4385782500 cites W2886402172 @default.
- W4385782500 cites W2910915966 @default.
- W4385782500 cites W2915203021 @default.
- W4385782500 cites W2964985647 @default.
- W4385782500 cites W2969984959 @default.
- W4385782500 cites W3042410501 @default.
- W4385782500 cites W3044109099 @default.
- W4385782500 cites W3135685607 @default.
- W4385782500 cites W3155745045 @default.
- W4385782500 cites W3164159456 @default.
- W4385782500 cites W3205209086 @default.
- W4385782500 cites W4200385483 @default.
- W4385782500 cites W4280500687 @default.
- W4385782500 cites W4281737395 @default.
- W4385782500 cites W4296492010 @default.
- W4385782500 cites W4362668199 @default.
- W4385782500 doi "https://doi.org/10.1186/s12967-023-04397-9" @default.
- W4385782500 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37573305" @default.
- W4385782500 hasPublicationYear "2023" @default.
- W4385782500 type Work @default.
- W4385782500 citedByCount "1" @default.
- W4385782500 countsByYear W43857825002023 @default.
- W4385782500 crossrefType "journal-article" @default.
- W4385782500 hasAuthorship W4385782500A5023909153 @default.
- W4385782500 hasAuthorship W4385782500A5033323312 @default.
- W4385782500 hasAuthorship W4385782500A5033398105 @default.
- W4385782500 hasAuthorship W4385782500A5041523906 @default.
- W4385782500 hasAuthorship W4385782500A5041528294 @default.
- W4385782500 hasAuthorship W4385782500A5056094455 @default.
- W4385782500 hasAuthorship W4385782500A5062895804 @default.
- W4385782500 hasAuthorship W4385782500A5063128754 @default.
- W4385782500 hasAuthorship W4385782500A5066832333 @default.
- W4385782500 hasAuthorship W4385782500A5087279801 @default.
- W4385782500 hasBestOaLocation W43857825001 @default.
- W4385782500 hasConcept C126322002 @default.
- W4385782500 hasConcept C142052008 @default.
- W4385782500 hasConcept C142724271 @default.
- W4385782500 hasConcept C144024400 @default.
- W4385782500 hasConcept C149923435 @default.
- W4385782500 hasConcept C156957248 @default.
- W4385782500 hasConcept C1862650 @default.
- W4385782500 hasConcept C2775854910 @default.
- W4385782500 hasConcept C2776541429 @default.
- W4385782500 hasConcept C2776886416 @default.
- W4385782500 hasConcept C2777083390 @default.
- W4385782500 hasConcept C2779329777 @default.
- W4385782500 hasConcept C2779874844 @default.
- W4385782500 hasConcept C2780221984 @default.
- W4385782500 hasConcept C2780586474 @default.
- W4385782500 hasConcept C2908647359 @default.
- W4385782500 hasConcept C511355011 @default.
- W4385782500 hasConcept C71924100 @default.
- W4385782500 hasConcept C99454951 @default.
- W4385782500 hasConceptScore W4385782500C126322002 @default.
- W4385782500 hasConceptScore W4385782500C142052008 @default.
- W4385782500 hasConceptScore W4385782500C142724271 @default.
- W4385782500 hasConceptScore W4385782500C144024400 @default.