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- W4385786370 endingPage "100409" @default.
- W4385786370 startingPage "100409" @default.
- W4385786370 abstract "The rapid development and spread of antimicrobial resistance in the post-antibiotic era has become a global concern. Recent evidence indicates that, at present, antibiotic resistance is evolving at an alarming rate as a defense mechanism against anthropogenic chemical stresses. Mechanistically, bacterial resistance to antibiotics involves reduced permeability, active efflux, modification of the target site, and/or inactivation of the antibiotic molecule and is encoded by antibiotic resistance genes (ARGs) that are majorly carried by mobile genetic elements (MGEs). Horizontal gene transfer (HGT) facilitates the inter and intra-species dissemination of MGEs and drives the spread of ARGs, which leads to the development of environmental resistome. Clinical and environmental antibiotic resistance has severe consequences on global health and the economy if left unchecked. For routine monitoring of the resistance, traditional culture-based methods, reliable polymerase chain reaction (PCR)-based methods, in addition to recent high throughput and rapid next-generation sequencing (NGS)-based methods, are often used. The present work critically reviews the mechanisms for the evolution of antimicrobial resistance, tools to monitor the emergence of such resistance and the global efforts for management of the growing threat of antimicrobial resistance spearheaded by the World Health Organization (WHO) in collaboration with developed and developing countries alike. The work highlights the policies at global and national levels to monitor and implement stewardship programs, awareness campaigns, prevention practices, and healthcare guidelines to promote and ensure the judicious prescription of antimicrobials for the containment of antimicrobial resistance." @default.
- W4385786370 created "2023-08-13" @default.
- W4385786370 creator A5002607059 @default.
- W4385786370 creator A5012608731 @default.
- W4385786370 creator A5050929291 @default.
- W4385786370 creator A5071064387 @default.
- W4385786370 date "2023-10-01" @default.
- W4385786370 modified "2023-10-17" @default.
- W4385786370 title "Emergence of environmental antibiotic resistance: Mechanism, monitoring and management" @default.
- W4385786370 cites W1137716852 @default.
- W4385786370 cites W1849979647 @default.
- W4385786370 cites W1965725897 @default.
- W4385786370 cites W1974123350 @default.
- W4385786370 cites W1975846399 @default.
- W4385786370 cites W1977376651 @default.
- W4385786370 cites W1979345248 @default.
- W4385786370 cites W1982634294 @default.
- W4385786370 cites W1988109375 @default.
- W4385786370 cites W1997607775 @default.
- W4385786370 cites W2016484793 @default.
- W4385786370 cites W2017760485 @default.
- W4385786370 cites W2023766026 @default.
- W4385786370 cites W2025759607 @default.
- W4385786370 cites W2036199362 @default.
- W4385786370 cites W2036978592 @default.
- W4385786370 cites W2037131746 @default.
- W4385786370 cites W2037456590 @default.
- W4385786370 cites W2040460736 @default.
- W4385786370 cites W2042742602 @default.
- W4385786370 cites W2055915619 @default.
- W4385786370 cites W2056294949 @default.
- W4385786370 cites W2058415702 @default.
- W4385786370 cites W2063107371 @default.
- W4385786370 cites W2073703928 @default.
- W4385786370 cites W2081183202 @default.
- W4385786370 cites W2092193084 @default.
- W4385786370 cites W2092643722 @default.
- W4385786370 cites W2109654313 @default.
- W4385786370 cites W2113326968 @default.
- W4385786370 cites W2113992635 @default.
- W4385786370 cites W2115443721 @default.
- W4385786370 cites W2118156419 @default.
- W4385786370 cites W2124308944 @default.
- W4385786370 cites W2126154952 @default.
- W4385786370 cites W2138380748 @default.
- W4385786370 cites W2140236384 @default.
- W4385786370 cites W2140465229 @default.
- W4385786370 cites W2143445148 @default.
- W4385786370 cites W2145213585 @default.
- W4385786370 cites W2150099463 @default.
- W4385786370 cites W2212546690 @default.
- W4385786370 cites W2301555865 @default.
- W4385786370 cites W2305920654 @default.
- W4385786370 cites W2341166238 @default.
- W4385786370 cites W2345670278 @default.
- W4385786370 cites W2521268641 @default.
- W4385786370 cites W2549136394 @default.
- W4385786370 cites W2556738030 @default.
- W4385786370 cites W2557121075 @default.
- W4385786370 cites W2558941103 @default.
- W4385786370 cites W2561512876 @default.
- W4385786370 cites W2575142694 @default.
- W4385786370 cites W2586590237 @default.
- W4385786370 cites W2589942572 @default.
- W4385786370 cites W2606692795 @default.
- W4385786370 cites W2610278254 @default.
- W4385786370 cites W2611877309 @default.
- W4385786370 cites W2616895225 @default.
- W4385786370 cites W2617234091 @default.
- W4385786370 cites W2657744962 @default.
- W4385786370 cites W2766146178 @default.
- W4385786370 cites W2766738717 @default.
- W4385786370 cites W2770063736 @default.
- W4385786370 cites W2773808769 @default.
- W4385786370 cites W2779019546 @default.
- W4385786370 cites W2782734361 @default.
- W4385786370 cites W2792701396 @default.
- W4385786370 cites W2793190632 @default.
- W4385786370 cites W2811512821 @default.
- W4385786370 cites W2836345977 @default.
- W4385786370 cites W2884980520 @default.
- W4385786370 cites W2889819256 @default.
- W4385786370 cites W2892679831 @default.
- W4385786370 cites W2895546391 @default.
- W4385786370 cites W2900503863 @default.
- W4385786370 cites W2900796598 @default.
- W4385786370 cites W2901209811 @default.
- W4385786370 cites W2902493574 @default.
- W4385786370 cites W2913714888 @default.
- W4385786370 cites W2914145461 @default.
- W4385786370 cites W2919372243 @default.
- W4385786370 cites W2920875400 @default.
- W4385786370 cites W2949826334 @default.
- W4385786370 cites W2956041925 @default.
- W4385786370 cites W2966075625 @default.
- W4385786370 cites W2966580525 @default.
- W4385786370 cites W2968322804 @default.
- W4385786370 cites W2969688130 @default.