FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385798631> ?p ?o ?g. }

• W4385798631 endingPage "275" @default.
• W4385798631 startingPage "268" @default.
• W4385798631 abstract "In many diabetic patients, spermatogenesis complications are frequent causing infertility problems. This study aimed to demonstrate the effect of Forskolin on male reproductive dysfunction caused by type 2 diabetes.In this experimental study, type 2 diabetes was induced by a high-fat diet (HFD) for one month and then a low single dose injection (35 mg/kg) of streptozotocin (STZ) in Wistar rats. After 72 hours, rats with more than 200 mg/dl of blood glucose were considered type 2 diabetic rats. Forty rats (200-250 g) were divided into four groups (n=10) including group 1 (G1): rats with normal diet and buffer citrate (STZ solvent) injection, group 2 (G2): control type 2 diabetic rats with HFD and STZ injection, group 3 (G3): type 2 diabetic rats received phosphate buffer saline (PBS) as Forskolin solvent, and group 4 (G4): Forskolin treated diabetic rats (10 mg/kg) for 1 month.In comparison to control group, in diabetic groups (G2 and G3) some parameters are increased significantly: The blood glucose (P=0.00078), testicular malondialdehyde (MDA) level and body weight (P=0.00009) and Bax gene expression (P=0.00007). Unlike, some parameters are decreased significantly: The serum level of testosterone (P=0.0009), testicular superoxide dismutase (SOD, P=0.00007) and glutathione peroxidase (GPX) levels (P=0.00008), sperm concentration (P=0.00008), motility (P=0.00009), normal morphological sperm (P=0.00008) and Bcl-2 gene expression (P=0.00009). However, in Forskolin treated group (G4) the parameters stayed close to control values that was significantly (P=0.00007) higher than in G2 and G3 groups. Therefore, treatment with Forskolin significantly improved these abnormal changes in Forskolin-treated group.Our study demonstrates that Forskolin is an effective antidiabetic agent, which significantly improves sperm concentration, testosterone levels, and antioxidant activity in diabetic rats." @default.
• W4385798631 created "2023-08-15" @default.
• W4385798631 creator A5029008361 @default.
• W4385798631 creator A5045899365 @default.
• W4385798631 creator A5046465486 @default.
• W4385798631 creator A5062818514 @default.
• W4385798631 creator A5062900263 @default.
• W4385798631 creator A5080408395 @default.
• W4385798631 date "2023-08-07" @default.
• W4385798631 modified "2023-09-25" @default.
• W4385798631 title "Forskolin Improves Male Reproductive Complications Caused by Hyperglycemia in Type 2 Diabetic Rats." @default.
• W4385798631 cites W1574386044 @default.
• W4385798631 cites W1750690213 @default.
• W4385798631 cites W1779694558 @default.
• W4385798631 cites W1892219175 @default.
• W4385798631 cites W1965259410 @default.
• W4385798631 cites W1974575214 @default.
• W4385798631 cites W1982371325 @default.
• W4385798631 cites W2015971144 @default.
• W4385798631 cites W2027827512 @default.
• W4385798631 cites W2058473208 @default.
• W4385798631 cites W2088012387 @default.
• W4385798631 cites W2108244474 @default.
• W4385798631 cites W2117921553 @default.
• W4385798631 cites W2141438284 @default.
• W4385798631 cites W2144994967 @default.
• W4385798631 cites W2145857061 @default.
• W4385798631 cites W2166862228 @default.
• W4385798631 cites W2168261002 @default.
• W4385798631 cites W2345328813 @default.
• W4385798631 cites W2615644497 @default.
• W4385798631 cites W2767825002 @default.
• W4385798631 cites W2778767107 @default.
• W4385798631 cites W2780517884 @default.
• W4385798631 cites W2781873092 @default.
• W4385798631 cites W2803183207 @default.
• W4385798631 cites W2887323028 @default.
• W4385798631 cites W2908496150 @default.
• W4385798631 cites W2911799919 @default.
• W4385798631 cites W2941829930 @default.
• W4385798631 cites W2943656785 @default.
• W4385798631 cites W2951703498 @default.
• W4385798631 cites W2991730925 @default.
• W4385798631 doi "https://doi.org/10.22074/ijfs.2022.544368.1235" @default.
• W4385798631 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37577911" @default.
• W4385798631 hasPublicationYear "2023" @default.
• W4385798631 type Work @default.
• W4385798631 citedByCount "0" @default.
• W4385798631 crossrefType "journal-article" @default.
• W4385798631 hasAuthorship W4385798631A5029008361 @default.
• W4385798631 hasAuthorship W4385798631A5045899365 @default.
• W4385798631 hasAuthorship W4385798631A5046465486 @default.
• W4385798631 hasAuthorship W4385798631A5062818514 @default.
• W4385798631 hasAuthorship W4385798631A5062900263 @default.
• W4385798631 hasAuthorship W4385798631A5080408395 @default.
• W4385798631 hasConcept C123765429 @default.
• W4385798631 hasConcept C126322002 @default.
• W4385798631 hasConcept C134018914 @default.
• W4385798631 hasConcept C16685009 @default.
• W4385798631 hasConcept C170493617 @default.
• W4385798631 hasConcept C2775838275 @default.
• W4385798631 hasConcept C2776151105 @default.
• W4385798631 hasConcept C2777632594 @default.
• W4385798631 hasConcept C2778401633 @default.
• W4385798631 hasConcept C2779276759 @default.
• W4385798631 hasConcept C2779280383 @default.
• W4385798631 hasConcept C2781087480 @default.
• W4385798631 hasConcept C555293320 @default.
• W4385798631 hasConcept C71924100 @default.
• W4385798631 hasConcept C86803240 @default.
• W4385798631 hasConceptScore W4385798631C123765429 @default.
• W4385798631 hasConceptScore W4385798631C126322002 @default.
• W4385798631 hasConceptScore W4385798631C134018914 @default.
• W4385798631 hasConceptScore W4385798631C16685009 @default.
• W4385798631 hasConceptScore W4385798631C170493617 @default.
• W4385798631 hasConceptScore W4385798631C2775838275 @default.
• W4385798631 hasConceptScore W4385798631C2776151105 @default.
• W4385798631 hasConceptScore W4385798631C2777632594 @default.
• W4385798631 hasConceptScore W4385798631C2778401633 @default.
• W4385798631 hasConceptScore W4385798631C2779276759 @default.
• W4385798631 hasConceptScore W4385798631C2779280383 @default.
• W4385798631 hasConceptScore W4385798631C2781087480 @default.
• W4385798631 hasConceptScore W4385798631C555293320 @default.
• W4385798631 hasConceptScore W4385798631C71924100 @default.
• W4385798631 hasConceptScore W4385798631C86803240 @default.
• W4385798631 hasIssue "4" @default.
• W4385798631 hasLocation W43857986311 @default.
• W4385798631 hasOpenAccess W4385798631 @default.
• W4385798631 hasPrimaryLocation W43857986311 @default.
• W4385798631 hasRelatedWork W1975696001 @default.
• W4385798631 hasRelatedWork W1995071802 @default.
• W4385798631 hasRelatedWork W2011709829 @default.
• W4385798631 hasRelatedWork W2053936620 @default.
• W4385798631 hasRelatedWork W2055342276 @default.
• W4385798631 hasRelatedWork W2089805841 @default.
• W4385798631 hasRelatedWork W2092993950 @default.
• W4385798631 hasRelatedWork W2095626059 @default.
• W4385798631 hasRelatedWork W2140892006 @default.

• next