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- W4385805366 endingPage "1199" @default.
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- W4385805366 abstract "This study aims to assess the efficacy of a psychoeducational family intervention (PFI) to reduce the severity of depressive symptoms and to improve psychosocial functioning and to increase social contacts in a sample of patients with major depressive disorder (MDD). The degree to which PFI will reduce patients' relapses, hospitalizations, and self-stigmatization and will improve their quality of life will also be assessed. Other secondary outcomes include the improvement of relatives' coping strategies, family burden, expressed emotions and quality of life. This non-profit, unfunded, national, multicentric randomized controlled trial with blinded outcome assessments will be carried out in 24 Italian university outpatient units. Families will be assessed at baseline and at 6, 12, and 24 months post-randomization. Our working hypothesis is that the PFIs will reduce the patients' severity of depressive symptoms, their relapses, and their hospitalizations, and that they will improve their psychosocial functioning and quality of life. We expect these results to be maintained after 12 and 24 months, albeit with a reduction in magnitude. The sample will consist of 384 patients randomized at a 1:1 ratio and stratified according to center, age, gender, and educational level." @default.
- W4385805366 created "2023-08-15" @default.
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- W4385805366 date "2023-08-13" @default.
- W4385805366 modified "2023-09-27" @default.
- W4385805366 title "The Efficacy of Psychoeducational Family Intervention for Major Depression: Study Protocol of a Randomized Controlled Trial" @default.
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- W4385805366 doi "https://doi.org/10.3390/brainsci13081199" @default.
- W4385805366 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37626555" @default.