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- W4385810876 abstract "In the middle of the 20th century, accumulating data suggested that DNA carries life’s genetic information. Biochemists around the world raced to determine its structure. The competition led to some notable misfires, such as Linus Pauling’s triple helix. In 1953, James Watson and Francis Crick published a pithy one-page article proposing that two helical ribose-phosphate backbones might form a double helix ( Nature , DOI: 10.1038/171737a0 ). They contended that hydrogen bonds might link the bases adenosine to thymine, and guanidine to cytosine between the two helical backbones, adding that the proposed structure “immediately suggests a possible copying mechanism for the genetic material.” In a famous controversy in science history, the discovery relied on X-ray crystallographic data collected by Rosalind Franklin , whose work neither Watson and Crick nor, later, the Nobel committee acknowledged. The work opened a new chapter in the life sciences. According to David Liu, a chemical" @default.
- W4385810876 created "2023-08-15" @default.
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- W4385810876 date "2023-08-14" @default.
- W4385810876 modified "2023-10-02" @default.
- W4385810876 title "Solving the structure of DNA" @default.
- W4385810876 doi "https://doi.org/10.1021/cen-10126-cover8" @default.
- W4385810876 hasPublicationYear "2023" @default.
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