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- W4385835335 abstract "<p>GSEA of the PBP signature-correlated genes. <b>A,</b> Bar plot shows the enriched Hallmark gene sets (FDR < 0.05) from GSEA of the KIPA-based PBP signature score-correlated genes at the protein levels. GSEA input was a ranked list of signed −log<sub>10</sub><i>P</i>-values from Pearson correlation between the KIPA-based PBP signature score and all the genes measured by the global proteomics in the CPTAC-TNBC dataset. Pathways with positive NES (normalized enrichment score) were positively correlated with the KIPA-based PBP signature score, while pathways with negative NES were negatively correlated. <b>B,</b> Enrichment plots for INTERFERON_GAMMA_RESPONSE Hallmark pathway at the protein levels. <b>C,</b> Bar plot shows the enriched Hallmark gene sets (FDR < 0.05) from GSEA of the KIPA-based PBP signature score-correlated genes at the mRNA levels. GSEA input was a ranked list of signed −log<sub>10</sub><i>P</i>-values from Pearson correlation between the KIPA-based PBP signature score and all the genes measured by the RNA-seq. <b>D,</b> Enrichment plots for INTERFERON_GAMMA_RESPONSE Hallmark pathway at the mRNA levels.</p>" @default.
- W4385835335 created "2023-08-16" @default.
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- W4385835335 date "2023-08-15" @default.
- W4385835335 modified "2023-09-27" @default.
- W4385835335 title "FIGURE 3 from Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins" @default.
- W4385835335 doi "https://doi.org/10.1158/2767-9764.23958053" @default.
- W4385835335 hasPublicationYear "2023" @default.
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