Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385836900> ?p ?o ?g. }
- W4385836900 abstract "Abstract Genes with multiple copies are likely to be maintained by stabilizing selection that puts a bound to unlimited expansion of copy number. We designed a model where copy number variation is generated by unequal recombination, which fits well to a number of genes, surveyed in three human populations. Based on this theoretical model and on computer simulations, we were interested in answering the question whether gene copy number distribution in the derived European and Asian populations can be explained by a purely demographic scenario or whether shifts in the distribution are signatures of adaptation. Although copy number distribution in most of the analyzed gene clusters can be explained by a bottleneck as in the out of Africa expansion of homo sapiens 60-10kyrs ago, we identified several candidate genes, for instance AMY1A and PGA3, whose copy numbers are likely to be selected differently among African, Asian and European populations." @default.
- W4385836900 created "2023-08-16" @default.
- W4385836900 creator A5061474554 @default.
- W4385836900 creator A5067935909 @default.
- W4385836900 creator A5087303026 @default.
- W4385836900 creator A5092641671 @default.
- W4385836900 date "2023-08-14" @default.
- W4385836900 modified "2023-10-03" @default.
- W4385836900 title "Distinguishing the roles of adaptation and demography in gene copy number changes in human populations" @default.
- W4385836900 cites W1588009429 @default.
- W4385836900 cites W1964379722 @default.
- W4385836900 cites W1976579731 @default.
- W4385836900 cites W1981761092 @default.
- W4385836900 cites W1989111033 @default.
- W4385836900 cites W1991713634 @default.
- W4385836900 cites W2007323090 @default.
- W4385836900 cites W2013812415 @default.
- W4385836900 cites W2059688400 @default.
- W4385836900 cites W2070589766 @default.
- W4385836900 cites W2085040521 @default.
- W4385836900 cites W2094846364 @default.
- W4385836900 cites W2100444509 @default.
- W4385836900 cites W2104579314 @default.
- W4385836900 cites W2113550562 @default.
- W4385836900 cites W2114610435 @default.
- W4385836900 cites W2124429242 @default.
- W4385836900 cites W2124873881 @default.
- W4385836900 cites W2129886940 @default.
- W4385836900 cites W2140472579 @default.
- W4385836900 cites W2144690533 @default.
- W4385836900 cites W2152015607 @default.
- W4385836900 cites W2155319238 @default.
- W4385836900 cites W2163809592 @default.
- W4385836900 cites W2289509647 @default.
- W4385836900 cites W2461811699 @default.
- W4385836900 cites W2556570102 @default.
- W4385836900 cites W2604856341 @default.
- W4385836900 cites W2773388190 @default.
- W4385836900 cites W2804736881 @default.
- W4385836900 cites W2891635311 @default.
- W4385836900 cites W2912408425 @default.
- W4385836900 cites W2914323379 @default.
- W4385836900 cites W2944958548 @default.
- W4385836900 cites W3007399904 @default.
- W4385836900 cites W3093039366 @default.
- W4385836900 cites W4224322757 @default.
- W4385836900 cites W4251304755 @default.
- W4385836900 cites W4376133202 @default.
- W4385836900 doi "https://doi.org/10.1101/2023.08.14.553171" @default.
- W4385836900 hasPublicationYear "2023" @default.
- W4385836900 type Work @default.
- W4385836900 citedByCount "0" @default.
- W4385836900 crossrefType "posted-content" @default.
- W4385836900 hasAuthorship W4385836900A5061474554 @default.
- W4385836900 hasAuthorship W4385836900A5067935909 @default.
- W4385836900 hasAuthorship W4385836900A5087303026 @default.
- W4385836900 hasAuthorship W4385836900A5092641671 @default.
- W4385836900 hasBestOaLocation W43858369001 @default.
- W4385836900 hasConcept C104317684 @default.
- W4385836900 hasConcept C110121322 @default.
- W4385836900 hasConcept C120821319 @default.
- W4385836900 hasConcept C134306372 @default.
- W4385836900 hasConcept C139807058 @default.
- W4385836900 hasConcept C141231307 @default.
- W4385836900 hasConcept C149635348 @default.
- W4385836900 hasConcept C154945302 @default.
- W4385836900 hasConcept C166957645 @default.
- W4385836900 hasConcept C169760540 @default.
- W4385836900 hasConcept C205649164 @default.
- W4385836900 hasConcept C2777938546 @default.
- W4385836900 hasConcept C2780513914 @default.
- W4385836900 hasConcept C33923547 @default.
- W4385836900 hasConcept C41008148 @default.
- W4385836900 hasConcept C54355233 @default.
- W4385836900 hasConcept C78458016 @default.
- W4385836900 hasConcept C81917197 @default.
- W4385836900 hasConcept C86803240 @default.
- W4385836900 hasConceptScore W4385836900C104317684 @default.
- W4385836900 hasConceptScore W4385836900C110121322 @default.
- W4385836900 hasConceptScore W4385836900C120821319 @default.
- W4385836900 hasConceptScore W4385836900C134306372 @default.
- W4385836900 hasConceptScore W4385836900C139807058 @default.
- W4385836900 hasConceptScore W4385836900C141231307 @default.
- W4385836900 hasConceptScore W4385836900C149635348 @default.
- W4385836900 hasConceptScore W4385836900C154945302 @default.
- W4385836900 hasConceptScore W4385836900C166957645 @default.
- W4385836900 hasConceptScore W4385836900C169760540 @default.
- W4385836900 hasConceptScore W4385836900C205649164 @default.
- W4385836900 hasConceptScore W4385836900C2777938546 @default.
- W4385836900 hasConceptScore W4385836900C2780513914 @default.
- W4385836900 hasConceptScore W4385836900C33923547 @default.
- W4385836900 hasConceptScore W4385836900C41008148 @default.
- W4385836900 hasConceptScore W4385836900C54355233 @default.
- W4385836900 hasConceptScore W4385836900C78458016 @default.
- W4385836900 hasConceptScore W4385836900C81917197 @default.
- W4385836900 hasConceptScore W4385836900C86803240 @default.
- W4385836900 hasLocation W43858369001 @default.
- W4385836900 hasOpenAccess W4385836900 @default.
- W4385836900 hasPrimaryLocation W43858369001 @default.
- W4385836900 hasRelatedWork W1202469404 @default.