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- W4385851708 abstract "Neck skin is thinner and has a more delicate dermal layer than facial skin. The studied product was specifically formulated for the neck combining a hydrating delivery system with a trifunctional corrective technology composed of 0.2% pure retinol, 2.5% tripeptide concentrate, and 5.0% glaucine complex to help improvement in signs of aging.To evaluate cosmetic and histologic changes 3 months after treatment using immunostains for Type I collagen, Type III collagen, and glycosaminoglycan (GAGS). In addition, overall clinical improvement in photoaged skin was measured by both Griffith's photonumeric photoaging scale, photographic improvement, and questionnaires.This study was an open-label, blinded clinical trial evaluating a combined retinol, tripeptide, and glaucine containing cream in the treatment of photo-aged skin. The study enrolled a total of 20 healthy male or female subjects, who applied the product for 3 months to their face and neck.Clinical as well histologic changes were consistent with improvement in all 20 subjects.Use of a combined retinol, tripeptide, and glaucine containing cream led to both clinical and histologic improvement of phototoaging." @default.
- W4385851708 created "2023-08-17" @default.
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- W4385851708 date "2023-08-16" @default.
- W4385851708 modified "2023-09-27" @default.
- W4385851708 title "Clinical and histologic findings after use of a novel combined retinol, tripeptide, and glaucine containing cream in the treatment of <scp>photo‐aged</scp> skin" @default.
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- W4385851708 doi "https://doi.org/10.1111/jocd.15945" @default.
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