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- W4385852541 abstract "AbstractNatural astaxanthin is synthesized by diverse organisms including: bacteria, fungi, microalgae, and plants involving complex cellular processes, which depend on numerous interrelated parameters. Nonetheless, existing knowledge regarding astaxanthin biosynthesis and the conditions influencing astaxanthin accumulation is fairly limited. Thus, manipulation of the growth conditions to achieve desired biomass and astaxanthin yields can be a complicated process requiring cost-intensive and time-consuming experiment-based research. As a potential solution, modeling and simulation of biological systems have recently emerged, allowing researchers to predict/estimate astaxanthin production dynamics in selected organisms. Moreover, mathematical modeling techniques would enable further optimization of astaxanthin synthesis in a shorter period of time, ultimately contributing to a notable reduction in production costs. Thus, the present review comprehensively discusses existing mathematical modeling techniques which simulate the bioaccumulation of astaxanthin in diverse organisms. Associated challenges, solutions, and future perspectives are critically analyzed and presented.Keywords: astaxanthinmathematical modelingmachine learningkinetic modelgenome-scale metabolic model AcknowledgmentsThe authors also gratefully acknowledge financial support from Taiwan’s Ministry of Science and Technology under grants MOST 111-3116-F-006 -004, 111-2621-M-029 -002, 110-2221-E-029 -004 -MY3, and 110-2622-E-110 -016.Disclosure statementNo potential conflict of interest was reported by the author(s)." @default.
- W4385852541 created "2023-08-17" @default.
- W4385852541 creator A5010348070 @default.
- W4385852541 creator A5015541122 @default.
- W4385852541 creator A5037892976 @default.
- W4385852541 creator A5061798804 @default.
- W4385852541 creator A5065503003 @default.
- W4385852541 creator A5091420795 @default.
- W4385852541 date "2023-08-16" @default.
- W4385852541 modified "2023-10-04" @default.
- W4385852541 title "Modeling of astaxanthin biosynthesis via machine learning, mathematical and metabolic network modeling" @default.
- W4385852541 cites W1557567888 @default.
- W4385852541 cites W1565527343 @default.
- W4385852541 cites W1813220146 @default.
- W4385852541 cites W196788542 @default.
- W4385852541 cites W1970818031 @default.
- W4385852541 cites W1973925220 @default.
- W4385852541 cites W1983085687 @default.
- W4385852541 cites W1985987493 @default.
- W4385852541 cites W1994479673 @default.
- W4385852541 cites W2002513372 @default.
- W4385852541 cites W2006410805 @default.
- W4385852541 cites W2008752688 @default.
- W4385852541 cites W2009884707 @default.
- W4385852541 cites W2009894386 @default.
- W4385852541 cites W2011385715 @default.
- W4385852541 cites W2014892517 @default.
- W4385852541 cites W2019062591 @default.
- W4385852541 cites W2027951156 @default.
- W4385852541 cites W2032548431 @default.
- W4385852541 cites W2036022984 @default.
- W4385852541 cites W2040919394 @default.
- W4385852541 cites W2048513083 @default.
- W4385852541 cites W2052159403 @default.
- W4385852541 cites W2053620213 @default.
- W4385852541 cites W2057783320 @default.
- W4385852541 cites W2058501095 @default.
- W4385852541 cites W2063261410 @default.
- W4385852541 cites W2076019128 @default.
- W4385852541 cites W2077491612 @default.
- W4385852541 cites W2082382448 @default.
- W4385852541 cites W2101805459 @default.
- W4385852541 cites W2105224249 @default.
- W4385852541 cites W2106827959 @default.
- W4385852541 cites W2110164995 @default.
- W4385852541 cites W2121223107 @default.
- W4385852541 cites W2133809942 @default.
- W4385852541 cites W2137219016 @default.
- W4385852541 cites W2137753831 @default.
- W4385852541 cites W2145343532 @default.
- W4385852541 cites W2145778689 @default.
- W4385852541 cites W2159303965 @default.
- W4385852541 cites W2164047130 @default.
- W4385852541 cites W2165638391 @default.
- W4385852541 cites W2185944647 @default.
- W4385852541 cites W2191505017 @default.
- W4385852541 cites W2223326830 @default.
- W4385852541 cites W2255099881 @default.
- W4385852541 cites W2461666696 @default.
- W4385852541 cites W2502938998 @default.
- W4385852541 cites W2517996958 @default.
- W4385852541 cites W2541389621 @default.
- W4385852541 cites W2564667983 @default.
- W4385852541 cites W2583459817 @default.
- W4385852541 cites W2603262085 @default.
- W4385852541 cites W2608257785 @default.
- W4385852541 cites W2614283331 @default.
- W4385852541 cites W2755021067 @default.
- W4385852541 cites W2768046673 @default.
- W4385852541 cites W2768918922 @default.
- W4385852541 cites W2771446683 @default.
- W4385852541 cites W2795024812 @default.
- W4385852541 cites W2802005696 @default.
- W4385852541 cites W2803255238 @default.
- W4385852541 cites W2886079965 @default.
- W4385852541 cites W2887049917 @default.
- W4385852541 cites W2887165975 @default.
- W4385852541 cites W2894226200 @default.
- W4385852541 cites W2896573181 @default.
- W4385852541 cites W2901218091 @default.
- W4385852541 cites W2901655845 @default.
- W4385852541 cites W2902406674 @default.
- W4385852541 cites W2906808820 @default.
- W4385852541 cites W2921190570 @default.
- W4385852541 cites W2943812859 @default.
- W4385852541 cites W2945103729 @default.
- W4385852541 cites W2948600471 @default.
- W4385852541 cites W2950882446 @default.
- W4385852541 cites W2952015518 @default.
- W4385852541 cites W2953321375 @default.
- W4385852541 cites W2962241699 @default.
- W4385852541 cites W2989896897 @default.
- W4385852541 cites W2999288267 @default.
- W4385852541 cites W3003470753 @default.
- W4385852541 cites W3005876359 @default.
- W4385852541 cites W3008690022 @default.
- W4385852541 cites W3011104190 @default.
- W4385852541 cites W3012466329 @default.