Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385852968> ?p ?o ?g. }
- W4385852968 abstract "Obesity is a disease commonly associated with urbanization and can also be characterized as a systemic, chronic metabolic condition resulting from an imbalance between energy intake and expenditure. The World Health Organization (WHO) has identified obesity as the most serious chronic disease that is increasingly prevalent in the world population. If left untreated, it can lead to dangerous health issues such as hypertension, hyperglycemia, hyperlipidemia, hyperuricemia, nonalcoholic steatohepatitis, atherosclerosis, and vulnerability to cardiovascular and cerebrovascular events. The specific mechanisms by which obesity affects the development of these diseases can be refined to the effect on immune cells. Existing studies have shown that the development of obesity and its associated diseases is closely related to the balance or lack thereof in the number and function of various immune cells, of which neutrophils are the most abundant immune cells in humans, infiltrating and accumulating in the adipose tissues of obese individuals, whereas NETosis, as a newly discovered type of neutrophil-related cell death, its role in the development of obesity and related diseases is increasingly emphasized. The article reviews the significant role that NETosis plays in the development of obesity and related diseases, such as diabetes and its complications. It discusses the epidemiology and negative impacts of obesity, explains the mechanisms of NETosis, and examines its potential as a targeted drug to treat obesity and associated ailments." @default.
- W4385852968 created "2023-08-17" @default.
- W4385852968 creator A5006651916 @default.
- W4385852968 creator A5011424458 @default.
- W4385852968 creator A5012897521 @default.
- W4385852968 creator A5029670581 @default.
- W4385852968 creator A5032481596 @default.
- W4385852968 creator A5033533946 @default.
- W4385852968 creator A5050705644 @default.
- W4385852968 creator A5063736296 @default.
- W4385852968 date "2023-08-15" @default.
- W4385852968 modified "2023-09-27" @default.
- W4385852968 title "The perspectives of NETosis on the progression of obesity and obesity-related diseases: mechanisms and applications" @default.
- W4385852968 cites W1534043095 @default.
- W4385852968 cites W1564279536 @default.
- W4385852968 cites W1574715084 @default.
- W4385852968 cites W1913879859 @default.
- W4385852968 cites W1925096404 @default.
- W4385852968 cites W1969161182 @default.
- W4385852968 cites W1980471591 @default.
- W4385852968 cites W1983219903 @default.
- W4385852968 cites W1987415392 @default.
- W4385852968 cites W1992687368 @default.
- W4385852968 cites W1998666012 @default.
- W4385852968 cites W1999967353 @default.
- W4385852968 cites W2000588983 @default.
- W4385852968 cites W2003475924 @default.
- W4385852968 cites W2004807994 @default.
- W4385852968 cites W2007493927 @default.
- W4385852968 cites W2009571354 @default.
- W4385852968 cites W2011779154 @default.
- W4385852968 cites W2013928401 @default.
- W4385852968 cites W2014901805 @default.
- W4385852968 cites W2024408216 @default.
- W4385852968 cites W2037342207 @default.
- W4385852968 cites W2041967652 @default.
- W4385852968 cites W2047877950 @default.
- W4385852968 cites W2049474811 @default.
- W4385852968 cites W2052372148 @default.
- W4385852968 cites W2053142936 @default.
- W4385852968 cites W2058244526 @default.
- W4385852968 cites W2061053728 @default.
- W4385852968 cites W2061309116 @default.
- W4385852968 cites W2067135721 @default.
- W4385852968 cites W2068992138 @default.
- W4385852968 cites W2088940658 @default.
- W4385852968 cites W2089093406 @default.
- W4385852968 cites W2092412521 @default.
- W4385852968 cites W2093824918 @default.
- W4385852968 cites W2095917499 @default.
- W4385852968 cites W2099356583 @default.
- W4385852968 cites W2102221395 @default.
- W4385852968 cites W2104934425 @default.
- W4385852968 cites W2107576987 @default.
- W4385852968 cites W2114041992 @default.
- W4385852968 cites W2129275826 @default.
- W4385852968 cites W2129694418 @default.
- W4385852968 cites W2131525958 @default.
- W4385852968 cites W2132116387 @default.
- W4385852968 cites W2133840693 @default.
- W4385852968 cites W2139710449 @default.
- W4385852968 cites W2144190812 @default.
- W4385852968 cites W2144211575 @default.
- W4385852968 cites W2148928984 @default.
- W4385852968 cites W2157459948 @default.
- W4385852968 cites W2158226607 @default.
- W4385852968 cites W2163587103 @default.
- W4385852968 cites W2167255704 @default.
- W4385852968 cites W2170651583 @default.
- W4385852968 cites W2170872320 @default.
- W4385852968 cites W2173066126 @default.
- W4385852968 cites W2175633126 @default.
- W4385852968 cites W2179822434 @default.
- W4385852968 cites W2254774777 @default.
- W4385852968 cites W2261479737 @default.
- W4385852968 cites W2268066121 @default.
- W4385852968 cites W2270530482 @default.
- W4385852968 cites W2273976251 @default.
- W4385852968 cites W2288325680 @default.
- W4385852968 cites W2301131921 @default.
- W4385852968 cites W2333203239 @default.
- W4385852968 cites W2338592593 @default.
- W4385852968 cites W2342532453 @default.
- W4385852968 cites W2405029429 @default.
- W4385852968 cites W2409408692 @default.
- W4385852968 cites W2464422420 @default.
- W4385852968 cites W2469229553 @default.
- W4385852968 cites W2501427606 @default.
- W4385852968 cites W2514386944 @default.
- W4385852968 cites W2566616762 @default.
- W4385852968 cites W2566985280 @default.
- W4385852968 cites W2586300905 @default.
- W4385852968 cites W2593144838 @default.
- W4385852968 cites W2594440831 @default.
- W4385852968 cites W2604953586 @default.
- W4385852968 cites W2730369070 @default.
- W4385852968 cites W2735376054 @default.
- W4385852968 cites W2736038609 @default.
- W4385852968 cites W2738355493 @default.
- W4385852968 cites W2753229994 @default.