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- W4385856812 endingPage "115654" @default.
- W4385856812 startingPage "115654" @default.
- W4385856812 abstract "On-line post separation sample manipulation is a powerful approach increasing the sensitivity and selectivity in chemical analysis. Post separation sample manipulation includes the treatment of the analytes after their separation through a suitable separation technique, mainly liquid chromatography and capillary electrophoresis. Typically, post separation approaches include either the addition of a reagent/solvent to derivatize the analyte/enhance the sensitivity, pH change, or the conversion of the analyte through a photochemical/electrochemical system (reagent–free systems). This review focuses on the developed methods using post-column manipulation of sample with pharmaceuticals and biomedical applications, covering the period from 2000 to midle-2023. Chemistries combined with fluorescence, UV–vis and mass spectrometric detection are discussed employing both liquid chromatography and electrophoretic techniques for separation. Noteworthy instrumental modifications are also discussed." @default.
- W4385856812 created "2023-08-17" @default.
- W4385856812 creator A5064903411 @default.
- W4385856812 creator A5082314920 @default.
- W4385856812 date "2023-10-01" @default.
- W4385856812 modified "2023-10-04" @default.
- W4385856812 title "Developments in on-line, post separation sample manipulation in the last 22 years: Pharmaceutical and biomedical applications" @default.
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