Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385873923> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4385873923 abstract "Fluoroalkylated compounds are important entities in agrochemicals, pharmaceuticals, and materials. The catalytic dicarbofunctionalization of alkenes represents a powerful strategy for the rapid construction and diversification of compounds. In this vein, multicomponent cross-coupling reactions (MC-CCR) can provide an efficient synthetic route to build molecular complexity. In this work, we report the first iron-catalyzed three-component fluoroalkylarylation of enamides via selective formation and trapping of alpha-amide radicals under mild conditions and fast reaction times. The reaction tolerates a variety of commercially available aryl Grignard reagents and fluoroalkyl halides. Finally, the use of a removable phthalimido group provides an efficient strategy to prepare highly valuable difluoroalkylated amines." @default.
- W4385873923 created "2023-08-17" @default.
- W4385873923 creator A5038942712 @default.
- W4385873923 creator A5046224682 @default.
- W4385873923 creator A5052700860 @default.
- W4385873923 creator A5092648777 @default.
- W4385873923 date "2023-08-16" @default.
- W4385873923 modified "2023-10-16" @default.
- W4385873923 title "Regioselective Fluoroalkylarylation of Enamides Enabled by an Iron-Catalyzed Multicomponent Radical Cross-Coupling Strategy" @default.
- W4385873923 doi "https://doi.org/10.26434/chemrxiv-2023-vtc6f" @default.
- W4385873923 hasPublicationYear "2023" @default.
- W4385873923 type Work @default.
- W4385873923 citedByCount "1" @default.
- W4385873923 crossrefType "posted-content" @default.
- W4385873923 hasAuthorship W4385873923A5038942712 @default.
- W4385873923 hasAuthorship W4385873923A5046224682 @default.
- W4385873923 hasAuthorship W4385873923A5052700860 @default.
- W4385873923 hasAuthorship W4385873923A5092648777 @default.
- W4385873923 hasBestOaLocation W43858739231 @default.
- W4385873923 hasConcept C139066938 @default.
- W4385873923 hasConcept C161790260 @default.
- W4385873923 hasConcept C178790620 @default.
- W4385873923 hasConcept C185592680 @default.
- W4385873923 hasConcept C21951064 @default.
- W4385873923 hasConcept C2778439535 @default.
- W4385873923 hasConcept C2780263894 @default.
- W4385873923 hasConcept C2781076698 @default.
- W4385873923 hasConcept C40875361 @default.
- W4385873923 hasConcept C59759590 @default.
- W4385873923 hasConceptScore W4385873923C139066938 @default.
- W4385873923 hasConceptScore W4385873923C161790260 @default.
- W4385873923 hasConceptScore W4385873923C178790620 @default.
- W4385873923 hasConceptScore W4385873923C185592680 @default.
- W4385873923 hasConceptScore W4385873923C21951064 @default.
- W4385873923 hasConceptScore W4385873923C2778439535 @default.
- W4385873923 hasConceptScore W4385873923C2780263894 @default.
- W4385873923 hasConceptScore W4385873923C2781076698 @default.
- W4385873923 hasConceptScore W4385873923C40875361 @default.
- W4385873923 hasConceptScore W4385873923C59759590 @default.
- W4385873923 hasLocation W43858739231 @default.
- W4385873923 hasOpenAccess W4385873923 @default.
- W4385873923 hasPrimaryLocation W43858739231 @default.
- W4385873923 hasRelatedWork W2058400330 @default.
- W4385873923 hasRelatedWork W2078466489 @default.
- W4385873923 hasRelatedWork W2342458827 @default.
- W4385873923 hasRelatedWork W2749840093 @default.
- W4385873923 hasRelatedWork W2767333537 @default.
- W4385873923 hasRelatedWork W2949709218 @default.
- W4385873923 hasRelatedWork W2951624391 @default.
- W4385873923 hasRelatedWork W2953155228 @default.
- W4385873923 hasRelatedWork W2999139619 @default.
- W4385873923 hasRelatedWork W4205637069 @default.
- W4385873923 isParatext "false" @default.
- W4385873923 isRetracted "false" @default.
- W4385873923 workType "article" @default.