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• W4385890245 abstract "This study aimed to evaluate the potential of 3D echo-planar imaging (EPI) for improving the reliability of $T_2^*$-weighted ($T_2^*w$) data and quantification of $textit{R}_2^*$ decay rate and susceptibility ($chi$) compared to conventional gradient echo (GRE)-based acquisition. Eight healthy subjects in a wide age range were recruited. Each subject received repeated scans for both GRE and EPI acquisitions with an isotropic 1 mm resolution at 3 T. Maps of $textit{R}_2^*$ and $chi$ were quantified and compared using their inter-scan difference to evaluate the test-retest reliability. Inter-protocol differences of $textit{R}_2^*$ and $chi$ between GRE and EPI were also measured voxel by voxel and in selected ROIs to test the consistency between the two acquisition methods. The quantifications of $textit{R}_2^*$ and $chi$ using EPI protocols showed increased test-retest reliability with higher EPI factors up to 5 as performed in the experiment and were consistent with those based on GRE. This result suggested multi-shot multi-echo 3D EPI can be a useful alternative acquisition method for $T_2^*w$ MRI and quantification of $textit{R}_2^*$ and $chi$ with reduced scan time, improved test-retest reliability and similar accuracy compared to commonly used 3D GRE." @default.
• W4385890245 created "2023-08-17" @default.
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• W4385890245 date "2023-08-15" @default.
• W4385890245 modified "2023-09-27" @default.
• W4385890245 title "Improved test-retest reliability of $textit{R}_2^*$ and susceptibility quantification using multi-shot multi echo 3D EPI." @default.
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