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- W4385969384 abstract "Along with the evolution process, the reproductive strategies evolved including oviparity, viviparity and ovoviviparity, to fit the residential environment maximize the survival rate of the off spring. In mammals, the key to the initiation of parturition is the inflammatory response at the maternal-fetal interface. As a proinflammatory cytokine, IL1β plays an important role in the process of human parturition. While, less is known about IL1β1 in teleost parturition. Aimed to identify the functions of IL1β1 in inducing the parturition, black rockfish, an ovoviviparity teleost, which provides over 60% nutrition supply for over 50 thousand embryos though a placenta like structure during pregnant, was employed as the research model. In the present study, based on the gene cloning, we detected the expression pattern of both Il1b1 and its receptor perinatal period, as well as the localization to the ovary by in situ hybridization. The different expression genes in transcriptomic data of perinatal primary ovarian cells treated with the recombinant IL1β1 (rIL1β1) obtained by prokaryotic expression system were analyzed. DEGs, functional enrichment and pathway analysis mainly included immune response, signal transduction and cell death. In summary, our research provides novel insights into the potential role of IL1β1 in the parturition of ovoviviparity teleost." @default.
- W4385969384 created "2023-08-19" @default.
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- W4385969384 date "2023-08-18" @default.
- W4385969384 modified "2023-10-06" @default.
- W4385969384 title "Pro-inflammatory cytokine IL1β1 participates in promoting parturition related pathways in the ovoviviparous teleost black rockfish (<i>Sebastes schlegelii</i>)" @default.
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- W4385969384 doi "https://doi.org/10.1093/biolre/ioad100" @default.
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