FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385969438> ?p ?o ?g. }

• W4385969438 endingPage "11" @default.
• W4385969438 startingPage "1" @default.
• W4385969438 abstract "ABSTRACTMacroautophagy/autophagy, is widely recognized for its crucial role in enabling cell survival and maintaining cellular energy homeostasis during starvation or energy stress. Its regulation is intricately linked to cellular energy status. In this review, covering yeast, mammals, and plants, we aim to provide a comprehensive overview of the understanding of the roles and mechanisms of carbon- or glucose-deprivation related autophagy, showing how cells effectively respond to such challenges for survival. Further investigation is needed to determine the specific degraded substrates by autophagy during glucose or energy deprivation and the diverse roles and mechanisms during varying durations of energy starvation.Abbreviations: ADP: adenosine diphosphate; AMP: adenosine monophosphate; AMPK: AMP-activated protein kinase; ATG: autophagy related; ATP: adenosine triphosphate; ER: endoplasmic reticulum; ESCRT: endosomal sorting complex required for transport; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GD: glucose deprivation; GFP: green fluorescent protein; GTPases: guanosine triphosphatases; HK2: hexokinase 2; K phaffii: Komagataella phaffii; LD: lipid droplet; MAP1LC3/LC3: microtubule-associated protein1 light chain 3; MAPK: mitogen-activated protein kinase; Mec1: mitosis entry checkpoint 1; MTOR: mechanistic target of rapamycin kinase; NAD (+): nicotinamide adenine dinucleotide; OGD: oxygen and glucose deprivation; PAS: phagophore assembly site; PCD: programmed cell death; PtdIns3K: class III phosphatidylinositol 3-kinase; PtdIns3P: phosphatidylinositol-3-phosphate; ROS: reactive oxygen species; S. cerevisiae: Saccharomyces cerevisiae; SIRT1: sirtuin 1; Snf1: sucrose non-fermenting 1; STK11/LKB1: serine/threonine kinase 11; TFEB: transcription factor EB; TORC1: target of rapamycin complex 1; ULK1: unc-51 like kinase 1; Vps27: vacuolar protein sorting 27; Vps4: vacuolar protein sorting 4.KEYWORDS: AMPKautophagycarbon starvationenergy metabolismglucose starvationSnf1 AcknowledgementsWe sincerely thank Prof. Do-Hyung Kim who has served as the editor. We thank the other members of the lab, especially Yingcong Chen, Weijing Yao and Yuting Chen, for their discussion in preparing this review. Figures were created using BioRender. This research was supported by the National Key Research and Development Program of China (2021YFC2600104) to Liqin Zhang, and National Natural Science Foundation of China (Grant No: 32122028, 92254307, and 32070739), Zhejiang Provincial Natural Science Foundation of China under Grant No.LR21C070001 to Cong Yi.Disclosure statementNo potential conflict of interest was reported by the author(s).Additional informationFundingThe work was supported by the National Key Research and Development Program of China [2021YFC2600104]; the National Science Foundation of China [32122028, 32070739, and 91754107]; and Zhejiang Provincial Natural Science Foundation of China [LR21C070001]." @default.
• W4385969438 created "2023-08-19" @default.
• W4385969438 creator A5000232053 @default.
• W4385969438 creator A5005642187 @default.
• W4385969438 creator A5023119724 @default.
• W4385969438 creator A5031881762 @default.
• W4385969438 creator A5040558103 @default.
• W4385969438 creator A5047231465 @default.
• W4385969438 creator A5048092270 @default.
• W4385969438 creator A5076458250 @default.
• W4385969438 date "2023-08-18" @default.
• W4385969438 modified "2023-10-15" @default.
• W4385969438 title "Interplay of energy metabolism and autophagy" @default.
• W4385969438 cites W1512253670 @default.
• W4385969438 cites W1706150252 @default.
• W4385969438 cites W1741052239 @default.
• W4385969438 cites W1769471103 @default.
• W4385969438 cites W1899014775 @default.
• W4385969438 cites W1913661755 @default.
• W4385969438 cites W1964338913 @default.
• W4385969438 cites W1970165340 @default.
• W4385969438 cites W1970637701 @default.
• W4385969438 cites W1973472942 @default.
• W4385969438 cites W1975190750 @default.
• W4385969438 cites W1976896999 @default.
• W4385969438 cites W1979141235 @default.
• W4385969438 cites W1986478574 @default.
• W4385969438 cites W1991470747 @default.
• W4385969438 cites W1991505853 @default.
• W4385969438 cites W1991798661 @default.
• W4385969438 cites W1992659717 @default.
• W4385969438 cites W1993902882 @default.
• W4385969438 cites W2001568034 @default.
• W4385969438 cites W2001591494 @default.
• W4385969438 cites W2001776102 @default.
• W4385969438 cites W2004814508 @default.
• W4385969438 cites W2005264361 @default.
• W4385969438 cites W2006393063 @default.
• W4385969438 cites W2007997314 @default.
• W4385969438 cites W2011043758 @default.
• W4385969438 cites W2014943313 @default.
• W4385969438 cites W2016615736 @default.
• W4385969438 cites W2017466590 @default.
• W4385969438 cites W2019073586 @default.
• W4385969438 cites W2020430280 @default.
• W4385969438 cites W2022101765 @default.
• W4385969438 cites W2027474840 @default.
• W4385969438 cites W2029856528 @default.
• W4385969438 cites W2033393684 @default.
• W4385969438 cites W2034911317 @default.
• W4385969438 cites W2035244376 @default.
• W4385969438 cites W2035444573 @default.
• W4385969438 cites W2039607936 @default.
• W4385969438 cites W2040656353 @default.
• W4385969438 cites W2042515284 @default.
• W4385969438 cites W2056137479 @default.
• W4385969438 cites W2059382856 @default.
• W4385969438 cites W2063980929 @default.
• W4385969438 cites W2070085869 @default.
• W4385969438 cites W2073883209 @default.
• W4385969438 cites W2078821200 @default.
• W4385969438 cites W2079580613 @default.
• W4385969438 cites W2081920342 @default.
• W4385969438 cites W2082476985 @default.
• W4385969438 cites W2091960020 @default.
• W4385969438 cites W2094989185 @default.
• W4385969438 cites W2101083009 @default.
• W4385969438 cites W2101569886 @default.
• W4385969438 cites W2102343982 @default.
• W4385969438 cites W2108318201 @default.
• W4385969438 cites W2109034822 @default.
• W4385969438 cites W2110898186 @default.
• W4385969438 cites W2111980604 @default.
• W4385969438 cites W2117692326 @default.
• W4385969438 cites W2126801593 @default.
• W4385969438 cites W2129687643 @default.
• W4385969438 cites W2141109717 @default.
• W4385969438 cites W2142505357 @default.
• W4385969438 cites W2147058114 @default.
• W4385969438 cites W2152389843 @default.
• W4385969438 cites W2152602200 @default.
• W4385969438 cites W2152855010 @default.
• W4385969438 cites W2156264079 @default.
• W4385969438 cites W2158303258 @default.
• W4385969438 cites W2162843846 @default.
• W4385969438 cites W2163419774 @default.
• W4385969438 cites W2167667054 @default.
• W4385969438 cites W2171520517 @default.
• W4385969438 cites W2177691638 @default.
• W4385969438 cites W2403964217 @default.
• W4385969438 cites W2408938666 @default.
• W4385969438 cites W2473146109 @default.
• W4385969438 cites W2507223877 @default.
• W4385969438 cites W2566889068 @default.
• W4385969438 cites W2605877384 @default.
• W4385969438 cites W2606187824 @default.
• W4385969438 cites W2609461401 @default.
• W4385969438 cites W2619622432 @default.

• next