Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385972571> ?p ?o ?g. }
- W4385972571 abstract "Abstract The present study was designed to evaluate whether elderberry (EB) effectively reduces inflammation and oxidative stress in hippocampal cells to modify seizure damage. Seizure was induced in rats by the injection of pentylenetetrazol (PTZ). In the Seizure + EB group, EB powder was added to the rats’ routine diet for eight consecutive weeks. The study included several behavioral tests, immunohistopathology, Voronoi tessellation (to estimate the spatial distribution of cells in the hippocampus), and Sholl analysis. The results in the Seizure + EB group showed an improvement in the behavioral aspects of the study, a reduction in astrogliosis, astrocyte process length, number of branches, and intersections distal to the soma in the hippocampus of rats compared to controls. Further analysis showed that EB diet increased nuclear factor-like 2 expression and decreased caspase-3 expression in the hippocampus in the Seizure + EB group. In addition, EB protected hippocampal pyramidal neurons from PTZ toxicity and improved the spatial distribution of hippocampal neurons in the pyramidal layer and dentate gyrus. The results of the present study suggest that EB can be considered a potent modifier of astrocyte reactivation and inflammatory responses." @default.
- W4385972571 created "2023-08-19" @default.
- W4385972571 creator A5012881201 @default.
- W4385972571 creator A5014040588 @default.
- W4385972571 creator A5018197814 @default.
- W4385972571 creator A5025743378 @default.
- W4385972571 creator A5042304352 @default.
- W4385972571 creator A5043258881 @default.
- W4385972571 creator A5043601272 @default.
- W4385972571 creator A5054909624 @default.
- W4385972571 creator A5063821991 @default.
- W4385972571 creator A5065686837 @default.
- W4385972571 creator A5081767186 @default.
- W4385972571 creator A5091160194 @default.
- W4385972571 creator A5091792634 @default.
- W4385972571 creator A5092660090 @default.
- W4385972571 date "2023-08-18" @default.
- W4385972571 modified "2023-10-06" @default.
- W4385972571 title "Anti-inflammatory and antioxidative effects of elderberry diet in the rat model of seizure: a behavioral and histological investigation on the hippocampus" @default.
- W4385972571 cites W1521523662 @default.
- W4385972571 cites W1566676785 @default.
- W4385972571 cites W1580746500 @default.
- W4385972571 cites W1925884394 @default.
- W4385972571 cites W1967986271 @default.
- W4385972571 cites W1972308802 @default.
- W4385972571 cites W1973109156 @default.
- W4385972571 cites W1977672676 @default.
- W4385972571 cites W1981134260 @default.
- W4385972571 cites W1987563935 @default.
- W4385972571 cites W1990355363 @default.
- W4385972571 cites W1995331974 @default.
- W4385972571 cites W1999952003 @default.
- W4385972571 cites W2007192205 @default.
- W4385972571 cites W2013693658 @default.
- W4385972571 cites W2013949808 @default.
- W4385972571 cites W2017899449 @default.
- W4385972571 cites W2034235846 @default.
- W4385972571 cites W2048399408 @default.
- W4385972571 cites W2060445540 @default.
- W4385972571 cites W2061497413 @default.
- W4385972571 cites W2078133424 @default.
- W4385972571 cites W2082559056 @default.
- W4385972571 cites W2092106059 @default.
- W4385972571 cites W2122873209 @default.
- W4385972571 cites W2133987553 @default.
- W4385972571 cites W2134729533 @default.
- W4385972571 cites W2134922993 @default.
- W4385972571 cites W2135663210 @default.
- W4385972571 cites W2136781825 @default.
- W4385972571 cites W2137832426 @default.
- W4385972571 cites W2139528091 @default.
- W4385972571 cites W2147502381 @default.
- W4385972571 cites W2150206235 @default.
- W4385972571 cites W2169403197 @default.
- W4385972571 cites W2204097464 @default.
- W4385972571 cites W2339909493 @default.
- W4385972571 cites W2606471454 @default.
- W4385972571 cites W2765463353 @default.
- W4385972571 cites W2778939421 @default.
- W4385972571 cites W2789750037 @default.
- W4385972571 cites W2792146806 @default.
- W4385972571 cites W2893778359 @default.
- W4385972571 cites W2912301948 @default.
- W4385972571 cites W2914658192 @default.
- W4385972571 cites W2962756413 @default.
- W4385972571 cites W2973089620 @default.
- W4385972571 cites W2979935062 @default.
- W4385972571 cites W2994172746 @default.
- W4385972571 cites W3021514239 @default.
- W4385972571 cites W3122380944 @default.
- W4385972571 cites W3136058679 @default.
- W4385972571 cites W3166974029 @default.
- W4385972571 cites W4230327365 @default.
- W4385972571 doi "https://doi.org/10.1093/toxres/tfad070" @default.
- W4385972571 hasPublicationYear "2023" @default.
- W4385972571 type Work @default.
- W4385972571 citedByCount "0" @default.
- W4385972571 crossrefType "journal-article" @default.
- W4385972571 hasAuthorship W4385972571A5012881201 @default.
- W4385972571 hasAuthorship W4385972571A5014040588 @default.
- W4385972571 hasAuthorship W4385972571A5018197814 @default.
- W4385972571 hasAuthorship W4385972571A5025743378 @default.
- W4385972571 hasAuthorship W4385972571A5042304352 @default.
- W4385972571 hasAuthorship W4385972571A5043258881 @default.
- W4385972571 hasAuthorship W4385972571A5043601272 @default.
- W4385972571 hasAuthorship W4385972571A5054909624 @default.
- W4385972571 hasAuthorship W4385972571A5063821991 @default.
- W4385972571 hasAuthorship W4385972571A5065686837 @default.
- W4385972571 hasAuthorship W4385972571A5081767186 @default.
- W4385972571 hasAuthorship W4385972571A5091160194 @default.
- W4385972571 hasAuthorship W4385972571A5091792634 @default.
- W4385972571 hasAuthorship W4385972571A5092660090 @default.
- W4385972571 hasConcept C126322002 @default.
- W4385972571 hasConcept C134018914 @default.
- W4385972571 hasConcept C148762608 @default.
- W4385972571 hasConcept C169760540 @default.
- W4385972571 hasConcept C185592680 @default.
- W4385972571 hasConcept C204232928 @default.
- W4385972571 hasConcept C2775858608 @default.
- W4385972571 hasConcept C2776464000 @default.