Matches in SemOpenAlex for { <https://semopenalex.org/work/W4385973037> ?p ?o ?g. }
- W4385973037 endingPage "107002" @default.
- W4385973037 startingPage "107002" @default.
- W4385973037 abstract "While Clostridium perfringens (C. perfringens) toxinotype F is known as the cause of 15% of antibiotic-associated diarrhea (AAD) and sporadic diarrhea (SD) cases, the association of the other C. perfringens toxinotypes with AAD/SD is not investigated. Therefore, the incidence of C. perfringens-associated diarrhea was investigated in hospitalized patients in six Iranian hospitals. A total of 151 stool specimens from AAD/SD patients were investigated for C. perfringens strains and the isolates were analyzed for the major (cpa, cpb, etx, and iap) and minor (cpe, cpb2, netb, PFO, and tpeL) toxin genes by PCR. C. perfringens isolation ratio was 28.5% (43 of 151 patients). C. perfringens isolation rates were not significant between different gender and age groups (p > 0.05), whereas it was significant between different wards and hospitals (p < 0.01). The cpa gene was detected in all C. perfringens isolates (n = 116). After that, the highest prevalence belonged to tpeL (87.1%), followed by pfo (84.5%), cpb2 (69.8%), cpe (55.2%), etx (12.9%), and netb (1.7%) genes. Based on these gene profiles, 35 (30.2%), 64 (55.2%), 15 (12.9%), and two (1.7%) isolates belonged to toxinotypes A, F, D, and G, respectively, and the other toxinotypes were not detected. This study persists in considering toxinotype F in Iranian AAD patients as it was the dominant C. perfringens toxinotype. Remarkably, the isolation of toxinotype D suggests it as a potential trigger in C. perfringens-associated AAD for the first time and highlights it as a possible zoonotic agent for humans." @default.
- W4385973037 created "2023-08-19" @default.
- W4385973037 creator A5022057476 @default.
- W4385973037 creator A5055588928 @default.
- W4385973037 date "2023-11-01" @default.
- W4385973037 modified "2023-10-14" @default.
- W4385973037 title "Prevalence of Clostridium perfringens toxinotypes in antibiotic-associated diarrheal (AAD) patients in Iranian hospitals; can toxinotype D serve as a possible zoonotic agent for humans?" @default.
- W4385973037 cites W123012820 @default.
- W4385973037 cites W1486649516 @default.
- W4385973037 cites W1493982916 @default.
- W4385973037 cites W1964630348 @default.
- W4385973037 cites W1968975029 @default.
- W4385973037 cites W2005589344 @default.
- W4385973037 cites W2022303042 @default.
- W4385973037 cites W2022385313 @default.
- W4385973037 cites W2031704987 @default.
- W4385973037 cites W2080192981 @default.
- W4385973037 cites W2080848411 @default.
- W4385973037 cites W2081157135 @default.
- W4385973037 cites W2096497004 @default.
- W4385973037 cites W2099792326 @default.
- W4385973037 cites W2108384191 @default.
- W4385973037 cites W2115810316 @default.
- W4385973037 cites W2117877004 @default.
- W4385973037 cites W2130222655 @default.
- W4385973037 cites W2131315598 @default.
- W4385973037 cites W2134267198 @default.
- W4385973037 cites W2134506669 @default.
- W4385973037 cites W2141998772 @default.
- W4385973037 cites W2143311335 @default.
- W4385973037 cites W2144852630 @default.
- W4385973037 cites W2161189106 @default.
- W4385973037 cites W2277430674 @default.
- W4385973037 cites W2329457112 @default.
- W4385973037 cites W2344100892 @default.
- W4385973037 cites W2799524357 @default.
- W4385973037 cites W2800937934 @default.
- W4385973037 cites W2885835166 @default.
- W4385973037 cites W2917542501 @default.
- W4385973037 cites W2919250846 @default.
- W4385973037 cites W2955990536 @default.
- W4385973037 cites W3155334985 @default.
- W4385973037 doi "https://doi.org/10.1016/j.actatropica.2023.107002" @default.
- W4385973037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37597720" @default.
- W4385973037 hasPublicationYear "2023" @default.
- W4385973037 type Work @default.
- W4385973037 citedByCount "0" @default.
- W4385973037 crossrefType "journal-article" @default.
- W4385973037 hasAuthorship W4385973037A5022057476 @default.
- W4385973037 hasAuthorship W4385973037A5055588928 @default.
- W4385973037 hasConcept C104317684 @default.
- W4385973037 hasConcept C120665830 @default.
- W4385973037 hasConcept C121332964 @default.
- W4385973037 hasConcept C126322002 @default.
- W4385973037 hasConcept C2775941552 @default.
- W4385973037 hasConcept C2777367657 @default.
- W4385973037 hasConcept C2779116991 @default.
- W4385973037 hasConcept C2779802037 @default.
- W4385973037 hasConcept C501593827 @default.
- W4385973037 hasConcept C523546767 @default.
- W4385973037 hasConcept C54355233 @default.
- W4385973037 hasConcept C547475151 @default.
- W4385973037 hasConcept C61511704 @default.
- W4385973037 hasConcept C66999527 @default.
- W4385973037 hasConcept C71924100 @default.
- W4385973037 hasConcept C86803240 @default.
- W4385973037 hasConcept C89423630 @default.
- W4385973037 hasConcept C90924648 @default.
- W4385973037 hasConceptScore W4385973037C104317684 @default.
- W4385973037 hasConceptScore W4385973037C120665830 @default.
- W4385973037 hasConceptScore W4385973037C121332964 @default.
- W4385973037 hasConceptScore W4385973037C126322002 @default.
- W4385973037 hasConceptScore W4385973037C2775941552 @default.
- W4385973037 hasConceptScore W4385973037C2777367657 @default.
- W4385973037 hasConceptScore W4385973037C2779116991 @default.
- W4385973037 hasConceptScore W4385973037C2779802037 @default.
- W4385973037 hasConceptScore W4385973037C501593827 @default.
- W4385973037 hasConceptScore W4385973037C523546767 @default.
- W4385973037 hasConceptScore W4385973037C54355233 @default.
- W4385973037 hasConceptScore W4385973037C547475151 @default.
- W4385973037 hasConceptScore W4385973037C61511704 @default.
- W4385973037 hasConceptScore W4385973037C66999527 @default.
- W4385973037 hasConceptScore W4385973037C71924100 @default.
- W4385973037 hasConceptScore W4385973037C86803240 @default.
- W4385973037 hasConceptScore W4385973037C89423630 @default.
- W4385973037 hasConceptScore W4385973037C90924648 @default.
- W4385973037 hasFunder F4320322776 @default.
- W4385973037 hasLocation W43859730371 @default.
- W4385973037 hasLocation W43859730372 @default.
- W4385973037 hasOpenAccess W4385973037 @default.
- W4385973037 hasPrimaryLocation W43859730371 @default.
- W4385973037 hasRelatedWork W165976480 @default.
- W4385973037 hasRelatedWork W1700331050 @default.
- W4385973037 hasRelatedWork W1978965890 @default.
- W4385973037 hasRelatedWork W204757711 @default.
- W4385973037 hasRelatedWork W2097470410 @default.
- W4385973037 hasRelatedWork W2156715030 @default.
- W4385973037 hasRelatedWork W2249359450 @default.