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- W4385997143 abstract "The current study examined the gene expression profiles of anabolic and catabolic molecules after a single parathyroid hormone (PTH) injection in mice. No significant changes were observed in alkaline phosphatase area/tissue volume, tartrate-resistant acid phosphatase–positive osteoclasts, or static bone histomorphometry parameters. However, a sudden and significant decrease in Runx2 expression occurred at 1.5 h post-injection followed by immediate elevation, while sclerostin level was initially downregulated but gradually recovered. Meanwhile, Rankl expression initially increased and then returned to baseline. The prolonged elevation of anabolic molecules and transient increase in catabolic molecules may contribute to the anabolic effect of PTH treatment." @default.
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- W4385997143 date "2023-08-01" @default.
- W4385997143 modified "2023-10-17" @default.
- W4385997143 title "Early gene expression profiles of anabolic and catabolic molecules in murine bone after a single PTH injection" @default.
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- W4385997143 doi "https://doi.org/10.1016/j.job.2023.08.003" @default.
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