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- W4386000187 abstract "SUMMARY Episodic memory involves encoding and remembering the order of events experienced over time. Previous work examining the mechanisms of temporal-order memories has focused on the hippocampus and prefrontal cortices but has largely ignored the memory ensembles in the medial posterior parietal cortex (mPPC). Combining in vivo multi-unit electrophysiology and a temporal-order judgment task with cinematic material in the macaque, we find that mPPC neuronal activity reflects temporal context both during encoding and recall. During learning, mPPC neuronal ensembles encode the temporal information embedded in the videos, whereas at retrieval these neurons fire in synchrony prior to memory-guided decisions. Moreover, the similarity between encoding and retrieval correlates with the animal’s performance. Together, these data suggest that neuronal activity in mPPC underpinning temporal-order memories." @default.
- W4386000187 created "2023-08-20" @default.
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- W4386000187 date "2023-08-18" @default.
- W4386000187 modified "2023-10-07" @default.
- W4386000187 title "Neural signatures for temporal-order memory in the medial posterior parietal cortex" @default.
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- W4386000187 doi "https://doi.org/10.1101/2023.08.17.553665" @default.
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