FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386002356> ?p ?o ?g. }

• W4386002356 abstract "Aims: Reactive oxygen species (ROS) are key regulators of plant growth, development and stress tolerance. Stress-induced changes in ROS levels trigger multilevel signalling. However, the precise mechanisms by which ROS signals are translated into changes in gene expression remain poorly defined. Focussing on six key antioxidant enzymes, we performed a meta-analysis of transcriptome data available in public databases to analyse ROS-mediated control of nuclear gene expression. Results: An information-guided pipeline was developed, which identified 19 putative transcription factors (TFs), as components in “common alarm signal cascade” pathway following perception of changes in ROS levels. Crucially, 30-35% of the abiotic stress transcriptome signatures had binding sites for common alarm signal-transcription Factors (CAS-TF) in their promoter regions. Further, PEAR2, DOF5.8 and OBP3 were identified as top-ranked TFs on the basis of cumulative DAPseq (DNA-affinity purification sequencing) score on the promoters of selected genes regulating core pathways of salt, drought, heat and cold stress tolerance. Innovation: This study identifies a set of CAS-TFs that may play a major role in shaping the transcriptome of abiotic stress induced ROS signalling. Ranking analysis identified PEAR2, DOF5.8 and OBP3 as top-ranked CAS-TFs that regulated known markers of abiotic stress-tolerance. Conclusion: The current findings suggest a major role of ROS in the abiotic stress signalling and also identifies as set of TFs that take part in the signalling. Taken together, these findings suggested that common alarm signal cascade underpins broad-range tolerance against multi-stress conditions. The identification of associated ROS-responsive CAS-TFs may provide novel targets for crop improvement." @default.
• W4386002356 created "2023-08-20" @default.
• W4386002356 creator A5035646542 @default.
• W4386002356 creator A5039931930 @default.
• W4386002356 creator A5050399895 @default.
• W4386002356 creator A5051896692 @default.
• W4386002356 creator A5061579085 @default.
• W4386002356 date "2023-08-19" @default.
• W4386002356 modified "2023-10-07" @default.
• W4386002356 title "Meta-analysis of antioxidant mutants reveals common-alarm signals for shaping abiotic stress-induced transcriptome in plants" @default.
• W4386002356 cites W1504340437 @default.
• W4386002356 cites W1959810190 @default.
• W4386002356 cites W1964324157 @default.
• W4386002356 cites W1976076241 @default.
• W4386002356 cites W1979904005 @default.
• W4386002356 cites W1980200149 @default.
• W4386002356 cites W1999607997 @default.
• W4386002356 cites W2024816837 @default.
• W4386002356 cites W2095442642 @default.
• W4386002356 cites W2126276072 @default.
• W4386002356 cites W2128644227 @default.
• W4386002356 cites W2133124877 @default.
• W4386002356 cites W2133766826 @default.
• W4386002356 cites W2143709071 @default.
• W4386002356 cites W2154140763 @default.
• W4386002356 cites W2157088050 @default.
• W4386002356 cites W2160901052 @default.
• W4386002356 cites W2161676651 @default.
• W4386002356 cites W2172292127 @default.
• W4386002356 cites W2412650228 @default.
• W4386002356 cites W2603125719 @default.
• W4386002356 cites W2604973478 @default.
• W4386002356 cites W2737873067 @default.
• W4386002356 cites W2895777606 @default.
• W4386002356 cites W2896418907 @default.
• W4386002356 cites W2922467277 @default.
• W4386002356 cites W2938302835 @default.
• W4386002356 cites W2944108475 @default.
• W4386002356 cites W2945575494 @default.
• W4386002356 cites W2989866276 @default.
• W4386002356 cites W2990329931 @default.
• W4386002356 cites W2997046468 @default.
• W4386002356 cites W3003041798 @default.
• W4386002356 cites W3023510889 @default.
• W4386002356 cites W3038320798 @default.
• W4386002356 cites W3046227827 @default.
• W4386002356 cites W3085693788 @default.
• W4386002356 cites W3093629995 @default.
• W4386002356 cites W3106397913 @default.
• W4386002356 cites W3108552872 @default.
• W4386002356 cites W3118046753 @default.
• W4386002356 cites W3118778904 @default.
• W4386002356 cites W3122836587 @default.
• W4386002356 cites W3170877162 @default.
• W4386002356 cites W3205888191 @default.
• W4386002356 cites W4224935967 @default.
• W4386002356 cites W4283575177 @default.
• W4386002356 cites W4294571369 @default.
• W4386002356 doi "https://doi.org/10.1089/ars.2023.0361" @default.
• W4386002356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37597205" @default.
• W4386002356 hasPublicationYear "2023" @default.
• W4386002356 type Work @default.
• W4386002356 citedByCount "0" @default.
• W4386002356 crossrefType "journal-article" @default.
• W4386002356 hasAuthorship W4386002356A5035646542 @default.
• W4386002356 hasAuthorship W4386002356A5039931930 @default.
• W4386002356 hasAuthorship W4386002356A5050399895 @default.
• W4386002356 hasAuthorship W4386002356A5051896692 @default.
• W4386002356 hasAuthorship W4386002356A5061579085 @default.
• W4386002356 hasConcept C104317684 @default.
• W4386002356 hasConcept C132215390 @default.
• W4386002356 hasConcept C150194340 @default.
• W4386002356 hasConcept C162317418 @default.
• W4386002356 hasConcept C18903297 @default.
• W4386002356 hasConcept C48349386 @default.
• W4386002356 hasConcept C54355233 @default.
• W4386002356 hasConcept C62478195 @default.
• W4386002356 hasConcept C70721500 @default.
• W4386002356 hasConcept C86339819 @default.
• W4386002356 hasConcept C86803240 @default.
• W4386002356 hasConcept C89519541 @default.
• W4386002356 hasConcept C95444343 @default.
• W4386002356 hasConceptScore W4386002356C104317684 @default.
• W4386002356 hasConceptScore W4386002356C132215390 @default.
• W4386002356 hasConceptScore W4386002356C150194340 @default.
• W4386002356 hasConceptScore W4386002356C162317418 @default.
• W4386002356 hasConceptScore W4386002356C18903297 @default.
• W4386002356 hasConceptScore W4386002356C48349386 @default.
• W4386002356 hasConceptScore W4386002356C54355233 @default.
• W4386002356 hasConceptScore W4386002356C62478195 @default.
• W4386002356 hasConceptScore W4386002356C70721500 @default.
• W4386002356 hasConceptScore W4386002356C86339819 @default.
• W4386002356 hasConceptScore W4386002356C86803240 @default.
• W4386002356 hasConceptScore W4386002356C89519541 @default.
• W4386002356 hasConceptScore W4386002356C95444343 @default.
• W4386002356 hasLocation W43860023561 @default.
• W4386002356 hasLocation W43860023562 @default.
• W4386002356 hasOpenAccess W4386002356 @default.
• W4386002356 hasPrimaryLocation W43860023561 @default.
• W4386002356 hasRelatedWork W2008091757 @default.

• next