Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386002600> ?p ?o ?g. }
- W4386002600 endingPage "104931" @default.
- W4386002600 startingPage "104931" @default.
- W4386002600 abstract "Grooming is a common readout in multiple rat models of neuropsychiatric diseases. It is usually associated with distress and negative emotionality, but also with emotional de-arousal after stress. These seemingly conflicting interpretations may result from specific grooming sequences appearing at different arousal levels and during distinct phases of the stress response. To further explore this hypothesis, we analyzed how distinct stressors affect grooming syntaxis and kinetics. To that end, we explored the independent and interacting effects of foot shocks, corticosterone (CORT), and novelty on exploratory activity, grooming, and ultrasonic vocalizations (USVs) in an open-field test (OF). Wistar rats were intraperitoneally injected either with vehicle or CORT, placed in a chamber where half of them were foot-shocked and then assessed in the OF. The next day, animals were re-exposed to the shock chamber and then tested in the OF without receiving any treatment. On day 1, foot shocks and –to a less extent CORT– increased freezing and inhibited rearing in the chamber, but only foot shocks increased distress USVs. In the OF, both treatments suppressed complex grooming, with foot-shocks also inhibiting exploration and CORT marginally reducing rearing. On day 2, foot-shocked rats showed conditioned fear when re-exposed to the chamber. When tested in the OF, foot-shocked and CORT-treated animals still showed low levels of complex grooming, with the former group also showing increased distress USVs. In this study, all different stressors inhibited complex grooming, suggesting an inverse association between these grooming subtypes and negative emotionality." @default.
- W4386002600 created "2023-08-20" @default.
- W4386002600 creator A5005076286 @default.
- W4386002600 creator A5021603975 @default.
- W4386002600 creator A5044447808 @default.
- W4386002600 date "2023-10-01" @default.
- W4386002600 modified "2023-10-17" @default.
- W4386002600 title "Distinct acute stressors exert an antagonistic effect on complex grooming during novelty habituation in rats" @default.
- W4386002600 cites W1507396199 @default.
- W4386002600 cites W1961324579 @default.
- W4386002600 cites W1969247680 @default.
- W4386002600 cites W1970539695 @default.
- W4386002600 cites W1977587850 @default.
- W4386002600 cites W1981389694 @default.
- W4386002600 cites W1982780621 @default.
- W4386002600 cites W1985144092 @default.
- W4386002600 cites W1986149871 @default.
- W4386002600 cites W1990351105 @default.
- W4386002600 cites W1990657338 @default.
- W4386002600 cites W2003164705 @default.
- W4386002600 cites W2016603062 @default.
- W4386002600 cites W2017612254 @default.
- W4386002600 cites W2020841767 @default.
- W4386002600 cites W2021746991 @default.
- W4386002600 cites W2025010605 @default.
- W4386002600 cites W2025231532 @default.
- W4386002600 cites W2026901177 @default.
- W4386002600 cites W2029220320 @default.
- W4386002600 cites W2030063067 @default.
- W4386002600 cites W2031508158 @default.
- W4386002600 cites W2031607006 @default.
- W4386002600 cites W2032410590 @default.
- W4386002600 cites W2034728437 @default.
- W4386002600 cites W2035286228 @default.
- W4386002600 cites W2043555306 @default.
- W4386002600 cites W2054647536 @default.
- W4386002600 cites W2063680945 @default.
- W4386002600 cites W2065254519 @default.
- W4386002600 cites W2070666079 @default.
- W4386002600 cites W2072212361 @default.
- W4386002600 cites W2073555254 @default.
- W4386002600 cites W2073868132 @default.
- W4386002600 cites W2083564112 @default.
- W4386002600 cites W2083851081 @default.
- W4386002600 cites W2091193930 @default.
- W4386002600 cites W2095083942 @default.
- W4386002600 cites W2108337057 @default.
- W4386002600 cites W2124972352 @default.
- W4386002600 cites W2127335433 @default.
- W4386002600 cites W2139440296 @default.
- W4386002600 cites W2139563646 @default.
- W4386002600 cites W2141747860 @default.
- W4386002600 cites W2154537724 @default.
- W4386002600 cites W2167830249 @default.
- W4386002600 cites W2178424481 @default.
- W4386002600 cites W2205794177 @default.
- W4386002600 cites W2238488421 @default.
- W4386002600 cites W2301329029 @default.
- W4386002600 cites W2413515606 @default.
- W4386002600 cites W2416371668 @default.
- W4386002600 cites W2436596660 @default.
- W4386002600 cites W2490725529 @default.
- W4386002600 cites W2497649352 @default.
- W4386002600 cites W255195117 @default.
- W4386002600 cites W2767792955 @default.
- W4386002600 cites W2771299374 @default.
- W4386002600 cites W2793439281 @default.
- W4386002600 cites W2885740370 @default.
- W4386002600 cites W2898761302 @default.
- W4386002600 cites W2904733902 @default.
- W4386002600 cites W2911726488 @default.
- W4386002600 cites W2913346441 @default.
- W4386002600 cites W2924648249 @default.
- W4386002600 cites W2950201206 @default.
- W4386002600 cites W2974053787 @default.
- W4386002600 cites W2990149589 @default.
- W4386002600 cites W2998371471 @default.
- W4386002600 cites W3003909283 @default.
- W4386002600 cites W3021109112 @default.
- W4386002600 cites W3024869186 @default.
- W4386002600 cites W3025616325 @default.
- W4386002600 cites W3129884138 @default.
- W4386002600 cites W3135425202 @default.
- W4386002600 cites W3210568072 @default.
- W4386002600 cites W4200486982 @default.
- W4386002600 cites W4224250099 @default.
- W4386002600 doi "https://doi.org/10.1016/j.beproc.2023.104931" @default.
- W4386002600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37598764" @default.
- W4386002600 hasPublicationYear "2023" @default.
- W4386002600 type Work @default.
- W4386002600 citedByCount "0" @default.
- W4386002600 crossrefType "journal-article" @default.
- W4386002600 hasAuthorship W4386002600A5005076286 @default.
- W4386002600 hasAuthorship W4386002600A5021603975 @default.
- W4386002600 hasAuthorship W4386002600A5044447808 @default.
- W4386002600 hasConcept C118552586 @default.
- W4386002600 hasConcept C125370674 @default.
- W4386002600 hasConcept C126322002 @default.