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• W4386002906 abstract "We describe a roadmap for a fully digital artificial intelligence (AI)-augmented nonclinical pathology laboratory across three continents. Underpinning the design are Good Laboratory Practice (GLP)-validated laboratory information management systems (LIMS), whole slide-scanners (WSS), image management systems (IMS), and a digital microscope intended for use by the nonclinical pathologist. Digital diagnostics are supported by tools that include AI-based virtual staining and deep learning-based decision support. Implemented during the COVID-19 pandemic, the initial digitized workflow largely mitigated disruption of pivotal nonclinical studies required to support pharmaceutical clinical testing. We believe that this digital transformation of our nonclinical pathology laboratories will promote efficiency and innovation in the future and enhance the quality and speed of drug development decision making." @default.
• W4386002906 created "2023-08-20" @default.
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• W4386002906 date "2023-10-01" @default.
• W4386002906 modified "2023-10-03" @default.
• W4386002906 title "Building a nonclinical pathology laboratory of the future for pharmaceutical research excellence" @default.
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• W4386002906 doi "https://doi.org/10.1016/j.drudis.2023.103747" @default.
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