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• W4386003345 endingPage "173619" @default.
• W4386003345 startingPage "173619" @default.
• W4386003345 abstract "The perception of social exclusion among patients with opioid use disorder (OUD) could be affected by long-term opioid use. This study explores the emotional and cardiac autonomic responses to an experience of ostracism in a sample of participants with OUD on opioid agonist treatment (OAT). Twenty patients with OUD and twenty healthy controls (HC) performed a ball-tossing game (Cyberball) with two conditions: Inclusion and Ostracism. We measured self-reported ratings of perceived threat towards one's fundamental needs and respiratory sinus arrhythmia (RSA) immediately after the game and 10 min after Ostracism (Reflective stage). Following ostracism, participants with OUD self-reported blunted feelings of threat to the fundamental need to belong. RSA levels were significantly suppressed immediately after ostracism and during the Reflective stage in comparison with HC, indicating an autonomic alteration in response to threatening social situations. Finally, only among HC higher perceived threats towards fundamental needs predicted increases in RSA levels, suggesting an adaptive vagal regulation in response to a perceived threat. Conversely, among patients with OUD the subjective response to ostracism was not associated with the autonomic reaction. OAT may have a protective effect against negative feelings of ostracism. However patients with OUD on OAT present poor autonomic regulation in response to social threats, which could reflect their trait hypersensitivity to social rejection." @default.
• W4386003345 created "2023-08-20" @default.
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• W4386003345 date "2023-10-01" @default.
• W4386003345 modified "2023-10-07" @default.
• W4386003345 title "Divergent emotional and autonomic responses to Cyberball in patients with opioid use disorder on opioid agonist treatment" @default.
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• W4386003345 doi "https://doi.org/10.1016/j.pbb.2023.173619" @default.
• W4386003345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37604318" @default.
• W4386003345 hasPublicationYear "2023" @default.
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