Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386003434> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W4386003434 endingPage "100650" @default.
- W4386003434 startingPage "100650" @default.
- W4386003434 abstract "Epigenetics and clinical observations referring to Betacoronavirus lead to the conjecture that Sarvecovirus may have the ability to infect lymphocytes using a different way than the spike protein. In addition to inducing the death of lymphocytes, thus drastically reducing their population and causing a serious immune deficiency, allows it to remain hidden for long periods of latency using them as a viral reservoir in what is named Long-Covid Disease. Exploring possibilities, the hypothesis is focused on that N protein may be the key of infecting lymphocytes. Method The present article exhibits a computational assay for the latest complete sequences reported to GISAID, correlating N genotypes with an enhancement in the affinity of the complex that causes immune deficiency in order to determine a good docking with the N protein and some receptors in lymphocytes. Results A novel high-interaction coupling of N-RBD and CD147 is presented as the main way of infecting lymphocytes, allowing to define those genotypes involved in their affinity enhancement. Conclusion The hypothesis is consistent with the mutagenic deriving observed on the in-silico assay, which reveals that genotypes N/120 and N/152 are determinant to reduce the Immune Response of the host infecting lymphocytes, allowing the virus persists indefinitely and causing an Acquire Immune Deficiency Syndrome." @default.
- W4386003434 created "2023-08-20" @default.
- W4386003434 creator A5024069545 @default.
- W4386003434 creator A5081264934 @default.
- W4386003434 creator A5092665708 @default.
- W4386003434 creator A5092665709 @default.
- W4386003434 date "2023-08-01" @default.
- W4386003434 modified "2023-09-25" @default.
- W4386003434 title "Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes" @default.
- W4386003434 cites W1726764148 @default.
- W4386003434 cites W1966929320 @default.
- W4386003434 cites W1969773218 @default.
- W4386003434 cites W2041352768 @default.
- W4386003434 cites W2050867439 @default.
- W4386003434 cites W2115897082 @default.
- W4386003434 cites W2130450914 @default.
- W4386003434 cites W2158066095 @default.
- W4386003434 cites W2610356532 @default.
- W4386003434 cites W2731784911 @default.
- W4386003434 cites W2768768130 @default.
- W4386003434 cites W2912436263 @default.
- W4386003434 cites W3009885589 @default.
- W4386003434 cites W3017251343 @default.
- W4386003434 cites W3032838347 @default.
- W4386003434 cites W3045649158 @default.
- W4386003434 cites W3082404514 @default.
- W4386003434 cites W3086897361 @default.
- W4386003434 cites W3136193945 @default.
- W4386003434 cites W3159596225 @default.
- W4386003434 cites W4220667558 @default.
- W4386003434 cites W4306910625 @default.
- W4386003434 cites W4385431983 @default.
- W4386003434 doi "https://doi.org/10.1016/j.bj.2023.100650" @default.
- W4386003434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37604249" @default.
- W4386003434 hasPublicationYear "2023" @default.
- W4386003434 type Work @default.
- W4386003434 citedByCount "0" @default.
- W4386003434 crossrefType "journal-article" @default.
- W4386003434 hasAuthorship W4386003434A5024069545 @default.
- W4386003434 hasAuthorship W4386003434A5081264934 @default.
- W4386003434 hasAuthorship W4386003434A5092665708 @default.
- W4386003434 hasAuthorship W4386003434A5092665709 @default.
- W4386003434 hasBestOaLocation W43860034341 @default.
- W4386003434 hasConcept C104317684 @default.
- W4386003434 hasConcept C135763542 @default.
- W4386003434 hasConcept C159047783 @default.
- W4386003434 hasConcept C203014093 @default.
- W4386003434 hasConcept C2522874641 @default.
- W4386003434 hasConcept C2775905019 @default.
- W4386003434 hasConcept C2776954793 @default.
- W4386003434 hasConcept C2777761686 @default.
- W4386003434 hasConcept C2908647359 @default.
- W4386003434 hasConcept C54355233 @default.
- W4386003434 hasConcept C71924100 @default.
- W4386003434 hasConcept C86803240 @default.
- W4386003434 hasConcept C8891405 @default.
- W4386003434 hasConcept C99454951 @default.
- W4386003434 hasConceptScore W4386003434C104317684 @default.
- W4386003434 hasConceptScore W4386003434C135763542 @default.
- W4386003434 hasConceptScore W4386003434C159047783 @default.
- W4386003434 hasConceptScore W4386003434C203014093 @default.
- W4386003434 hasConceptScore W4386003434C2522874641 @default.
- W4386003434 hasConceptScore W4386003434C2775905019 @default.
- W4386003434 hasConceptScore W4386003434C2776954793 @default.
- W4386003434 hasConceptScore W4386003434C2777761686 @default.
- W4386003434 hasConceptScore W4386003434C2908647359 @default.
- W4386003434 hasConceptScore W4386003434C54355233 @default.
- W4386003434 hasConceptScore W4386003434C71924100 @default.
- W4386003434 hasConceptScore W4386003434C86803240 @default.
- W4386003434 hasConceptScore W4386003434C8891405 @default.
- W4386003434 hasConceptScore W4386003434C99454951 @default.
- W4386003434 hasLocation W43860034341 @default.
- W4386003434 hasLocation W43860034342 @default.
- W4386003434 hasOpenAccess W4386003434 @default.
- W4386003434 hasPrimaryLocation W43860034341 @default.
- W4386003434 hasRelatedWork W1506984959 @default.
- W4386003434 hasRelatedWork W1991523530 @default.
- W4386003434 hasRelatedWork W2002128513 @default.
- W4386003434 hasRelatedWork W2016551366 @default.
- W4386003434 hasRelatedWork W2020824267 @default.
- W4386003434 hasRelatedWork W2056385328 @default.
- W4386003434 hasRelatedWork W2149871822 @default.
- W4386003434 hasRelatedWork W2153196018 @default.
- W4386003434 hasRelatedWork W91868852 @default.
- W4386003434 hasRelatedWork W2092874662 @default.
- W4386003434 isParatext "false" @default.
- W4386003434 isRetracted "false" @default.
- W4386003434 workType "article" @default.