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- W4386004018 abstract "Abstract Objectives: To investigate the value of PLR and LMR at admission for predicting in-hospital mortality in elderly patients with hip fracture (HF). Design: Prospective study. Setting: Academic, Level 1 trauma centre. Intervention: None Main Outcome Measurement:In-hospital mortality. Patients: Main cohort: 1,256 consecutive HF patients (mean age 82.9 ± 8.7 years, 73.5% females), validation cohort: 582 HF patients (mean age 81.9 ± 9.13 years, 71.0% females). Results: The in-hospital mortality rate was 5.0% (n=64) in the main cohort and 4.1% (n=24) in the validation cohort. Both elevated PLR (>280) and low LMR (<1.1) were significant independent prognostic indicators of hospital mortality. In aged >80 years with abnormal PLR or LMR, the risk of a fatal outcome was about 3-fold higher compared to the rest of the cohort and 1015-fold higher compared to individuals without both characteristics. Admission PLR or LMR were highly predictive for a fatal outcome in patients aged >80 with comorbidities (CAD, CKD, COPD, dementia): area under the curve ranged between 0.827 and 0.873 and the number of patients needed to be examined for correct prediction ranged between 3.9 and 7.6. In the validation cohort, the admission PLR and LMR produced similar predictive values. Conclusions: In HF patients, PLR and LMR at admission are independent prognostic indicators of in-hospital mortality and in combination with age >80 and certain comorbidities are strong predictors of survival. Level of Evidence: Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence." @default.
- W4386004018 created "2023-08-20" @default.
- W4386004018 date "2023-07-12" @default.
- W4386004018 modified "2023-09-23" @default.
- W4386004018 title "Platelet-to-Lymphocyte Ratio (PLR) and Lymphocyte-to-Monocyte Ratio (LMR) at Admission Predict Survival in Hip Fracture Patients" @default.
- W4386004018 doi "https://doi.org/10.29011/2575-8241.001311" @default.
- W4386004018 hasPublicationYear "2023" @default.
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