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- W4386007974 abstract "The mechanisms and implications underlying cognitive decline, mild cognitive impairment (MCI), and dementia in Type 2 diabetes mellitus (T2DM) have deserved high attention in recent years since a large number of studies has found that T2DM may increase their incidence rate (Biessels andDespa, 2018, Husain et al., 2023). In this Research Topic, two works addressed interesting aspects of this issue. First, a systematic review by Long et al. (2023) on the potential efficacy of intranasal (IN) insulin in improving cognitive function in people with MCI/dementia, without exerting undesirable peripheral hypoglycemia (Craft et al., 1996;2020) In all groups, spleen organometrics correlated with frailty index, but AD-specific salient functional 90 correlations (corticosterone levels with worse memory performance, and lower splenic GPx 91 antioxidant enzymatic activity, a potent risk of morbidity and mortality in AD) were identified. 92The present works contribute to identifying the crosstalk between different mechanisms, better 93 understanding the brain, and providing insights for novel preventive/therapeutical strategy targeting. 94" @default.
- W4386007974 created "2023-08-20" @default.
- W4386007974 creator A5013651495 @default.
- W4386007974 date "2023-08-18" @default.
- W4386007974 modified "2023-09-25" @default.
- W4386007974 title "Editorial: The crosstalk of different mechanisms in cognitive impairment associated with aging, Alzheimer's disease, and related dementias" @default.
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- W4386007974 doi "https://doi.org/10.3389/fnagi.2023.1258893" @default.
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