FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386021789> ?p ?o ?g. }

• W4386021789 endingPage "S38" @default.
• W4386021789 startingPage "S37" @default.
• W4386021789 abstract "BACKGROUND CONTEXT Cervical total disc arthroplasty has become a popular treatment for cervical degenerative disc disease as it preserves motion and is thought to prevent adjacent level disease compared to ACDF. The sensitivity of implant height on biomechanics in cervical arthroplasty is currently unknown. PURPOSE The aim of this study was to determine the effect of various instrumentation constructs on biomechanics of cervical spine. The constructs included 1- and 2-level disc arthroplasty, overstuffing, hybrid, and 2-level fusion. STUDY DESIGN/SETTING A human cadaveric biomechanical study. METHODS Eight cervical spine specimens (C2-T1) were subjected to flexion-extension loading up to 2 Nm using a dual gimbal, six degree-of-freedom servo-hydraulic spine simulator. Motion was tracked using an optoelectronic system. Each specimen was tested in the native state and in five different intervention constructs: 1-level cTDA, 2-level cTDA, 2-level cTDA with one device oversized by 1 mm, hybrid, and 2-level fusion with ACDF and posterior fusion. Range of motion (ROM) were compared between the six different interventions at the total cervical spine, index levels, and adjacent levels. RESULTS The introduction of a mobile-core cTDA device replicated healthy native range of motion at 1- and 2-levels. The overstuffed, hybrid, and 2-level fusion interventions all caused significant drops in total cervical ROM compared to the intact, 1-level, and 2-level cTDA interventions. Overstuffing one level of a cTDA device by 1 mm resulted in a significant 15% drop in total cervical range of motion, and no significant differences were recorded between the hybrid and overstuffed interventions. CONCLUSIONS The fact that oversizing the MCD by 1mm reduced the overall index ROM by over half has important implications for spine surgeons and device manufacturers in creating appropriately sized implants. This study demonstrates that even 1mm change in a TDA device can drastically change ROM over the entire cervical spine. Therefore, a wider selection of device sizes may be of great benefit to patients in the future, particularly as the popularity of the TDA procedure increases in the coming decades. FDA Device/Drug Status This abstract does not discuss or include any applicable devices or drugs. Cervical total disc arthroplasty has become a popular treatment for cervical degenerative disc disease as it preserves motion and is thought to prevent adjacent level disease compared to ACDF. The sensitivity of implant height on biomechanics in cervical arthroplasty is currently unknown. The aim of this study was to determine the effect of various instrumentation constructs on biomechanics of cervical spine. The constructs included 1- and 2-level disc arthroplasty, overstuffing, hybrid, and 2-level fusion. A human cadaveric biomechanical study. Eight cervical spine specimens (C2-T1) were subjected to flexion-extension loading up to 2 Nm using a dual gimbal, six degree-of-freedom servo-hydraulic spine simulator. Motion was tracked using an optoelectronic system. Each specimen was tested in the native state and in five different intervention constructs: 1-level cTDA, 2-level cTDA, 2-level cTDA with one device oversized by 1 mm, hybrid, and 2-level fusion with ACDF and posterior fusion. Range of motion (ROM) were compared between the six different interventions at the total cervical spine, index levels, and adjacent levels. The introduction of a mobile-core cTDA device replicated healthy native range of motion at 1- and 2-levels. The overstuffed, hybrid, and 2-level fusion interventions all caused significant drops in total cervical ROM compared to the intact, 1-level, and 2-level cTDA interventions. Overstuffing one level of a cTDA device by 1 mm resulted in a significant 15% drop in total cervical range of motion, and no significant differences were recorded between the hybrid and overstuffed interventions. The fact that oversizing the MCD by 1mm reduced the overall index ROM by over half has important implications for spine surgeons and device manufacturers in creating appropriately sized implants. This study demonstrates that even 1mm change in a TDA device can drastically change ROM over the entire cervical spine. Therefore, a wider selection of device sizes may be of great benefit to patients in the future, particularly as the popularity of the TDA procedure increases in the coming decades." @default.
• W4386021789 created "2023-08-22" @default.
• W4386021789 creator A5008820870 @default.
• W4386021789 creator A5053317385 @default.
• W4386021789 date "2023-09-01" @default.
• W4386021789 modified "2023-10-09" @default.
• W4386021789 title "72. How does overstuffing affect ROM in cTDA? A biomechanics study" @default.
• W4386021789 doi "https://doi.org/10.1016/j.spinee.2023.06.124" @default.
• W4386021789 hasPublicationYear "2023" @default.
• W4386021789 type Work @default.
• W4386021789 citedByCount "0" @default.
• W4386021789 crossrefType "journal-article" @default.
• W4386021789 hasAuthorship W4386021789A5008820870 @default.
• W4386021789 hasAuthorship W4386021789A5053317385 @default.
• W4386021789 hasConcept C105702510 @default.
• W4386021789 hasConcept C141071460 @default.
• W4386021789 hasConcept C151730666 @default.
• W4386021789 hasConcept C170700871 @default.
• W4386021789 hasConcept C175696284 @default.
• W4386021789 hasConcept C1862650 @default.
• W4386021789 hasConcept C2778051963 @default.
• W4386021789 hasConcept C2778336525 @default.
• W4386021789 hasConcept C2779343474 @default.
• W4386021789 hasConcept C2781411149 @default.
• W4386021789 hasConcept C29694066 @default.
• W4386021789 hasConcept C2985379065 @default.
• W4386021789 hasConcept C44575665 @default.
• W4386021789 hasConcept C60465272 @default.
• W4386021789 hasConcept C71924100 @default.
• W4386021789 hasConcept C86803240 @default.
• W4386021789 hasConceptScore W4386021789C105702510 @default.
• W4386021789 hasConceptScore W4386021789C141071460 @default.
• W4386021789 hasConceptScore W4386021789C151730666 @default.
• W4386021789 hasConceptScore W4386021789C170700871 @default.
• W4386021789 hasConceptScore W4386021789C175696284 @default.
• W4386021789 hasConceptScore W4386021789C1862650 @default.
• W4386021789 hasConceptScore W4386021789C2778051963 @default.
• W4386021789 hasConceptScore W4386021789C2778336525 @default.
• W4386021789 hasConceptScore W4386021789C2779343474 @default.
• W4386021789 hasConceptScore W4386021789C2781411149 @default.
• W4386021789 hasConceptScore W4386021789C29694066 @default.
• W4386021789 hasConceptScore W4386021789C2985379065 @default.
• W4386021789 hasConceptScore W4386021789C44575665 @default.
• W4386021789 hasConceptScore W4386021789C60465272 @default.
• W4386021789 hasConceptScore W4386021789C71924100 @default.
• W4386021789 hasConceptScore W4386021789C86803240 @default.
• W4386021789 hasIssue "9" @default.
• W4386021789 hasLocation W43860217891 @default.
• W4386021789 hasOpenAccess W4386021789 @default.
• W4386021789 hasPrimaryLocation W43860217891 @default.
• W4386021789 hasRelatedWork W2036277705 @default.
• W4386021789 hasRelatedWork W2089721111 @default.
• W4386021789 hasRelatedWork W2102235769 @default.
• W4386021789 hasRelatedWork W2126297224 @default.
• W4386021789 hasRelatedWork W2325655734 @default.
• W4386021789 hasRelatedWork W2329930699 @default.
• W4386021789 hasRelatedWork W2408807698 @default.
• W4386021789 hasRelatedWork W2901066969 @default.
• W4386021789 hasRelatedWork W3084427759 @default.
• W4386021789 hasRelatedWork W3128059097 @default.
• W4386021789 hasVolume "23" @default.
• W4386021789 isParatext "false" @default.
• W4386021789 isRetracted "false" @default.
• W4386021789 workType "article" @default.