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• W4386023701 abstract "Abstract The growing availability of single-cell and spatially-resolved transcriptomics has led to the rapidly growing popularity of methods to infer cell-cell communication. Many approaches have emerged, each capturing only a partial view of the complex landscape of cell-cell communication. Here, we present LIANA+, a scalable framework to decode coordinated inter- and intracellular signalling events from single- and multi-condition datasets in both single-cell and spatially-resolved data. Beyond integrating and extending established methodologies and a rich knowledge base, LIANA+ enables novel analyses using diverse molecular mediators, including those measured in multi-omics data. Accessible as an open-source Python package at https://github.com/saezlab/liana-py , LIANA+ provides a comprehensive set of synergistic components to study cell-cell communication. Abstract Figure" @default.
• W4386023701 created "2023-08-22" @default.
• W4386023701 creator A5005499510 @default.
• W4386023701 creator A5006843566 @default.
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• W4386023701 creator A5037274841 @default.
• W4386023701 creator A5037342361 @default.
• W4386023701 creator A5069139627 @default.
• W4386023701 creator A5084832725 @default.
• W4386023701 date "2023-08-21" @default.
• W4386023701 modified "2023-09-26" @default.
• W4386023701 title "LIANA+: an all-in-one cell-cell communication framework" @default.
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