Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386025835> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W4386025835 endingPage "6" @default.
- W4386025835 startingPage "1" @default.
- W4386025835 abstract "<italic xmlns:mml=http://www.w3.org/1998/Math/MathML xmlns:xlink=http://www.w3.org/1999/xlink>Objective:</i> Calcium imaging is an essential tool for obtaining neuroactivities to understand the complex function of the brain. The one-photon miniscope, the most widely used endoscope in neuroscience, is employed to record neuronal calcium activities in vivo. However, the current half ball lens overlooks the energy distribution in the brain field, resulting in non-uniform fluorescence imaging and the omission of important signals, leading to misunderstanding in brain science. The main flaw in the existing lens is the lack of controlled energy distribution, where the center fluorescence is much stronger than the edge area, causing the fluorescence noisy background to overlap with numerous neuron signals. To address this issue, we propose a novel approach to simplify the optical path by setting a medial target. By combining the Ray Mapping Method and Energy Feedback Method, we design and optimize the lens based on the energy mapping mesh. Simulation results demonstrate a 2.1-fold enhancement in energy distribution uniformity in the brain field compared to the original half-ball lens, with edge neurons receiving 6.95 times more energy. This novel design is theoretically proved to be an innovative improvement of the one-photon miniscope method, being a potential breakthrough of this mainstream method lasting more than ten years." @default.
- W4386025835 created "2023-08-22" @default.
- W4386025835 creator A5004820093 @default.
- W4386025835 creator A5065509814 @default.
- W4386025835 date "2023-10-01" @default.
- W4386025835 modified "2023-10-10" @default.
- W4386025835 title "A novel Design Method of Uniformity Energy Distribution Lens for Miniscopes" @default.
- W4386025835 cites W1654207600 @default.
- W4386025835 cites W1828521445 @default.
- W4386025835 cites W1983157591 @default.
- W4386025835 cites W1991438666 @default.
- W4386025835 cites W2009350638 @default.
- W4386025835 cites W2027898754 @default.
- W4386025835 cites W2041335422 @default.
- W4386025835 cites W2041656098 @default.
- W4386025835 cites W2057039357 @default.
- W4386025835 cites W2064549544 @default.
- W4386025835 cites W2077374589 @default.
- W4386025835 cites W2096860047 @default.
- W4386025835 cites W2265560249 @default.
- W4386025835 cites W2525578234 @default.
- W4386025835 cites W2541855997 @default.
- W4386025835 cites W2567463709 @default.
- W4386025835 cites W2602668040 @default.
- W4386025835 cites W2607724497 @default.
- W4386025835 cites W2768625854 @default.
- W4386025835 cites W2801687479 @default.
- W4386025835 cites W2805271873 @default.
- W4386025835 cites W2903604081 @default.
- W4386025835 cites W2904701107 @default.
- W4386025835 cites W2952986861 @default.
- W4386025835 cites W2989747923 @default.
- W4386025835 cites W4220947224 @default.
- W4386025835 cites W4284890130 @default.
- W4386025835 cites W4291624870 @default.
- W4386025835 doi "https://doi.org/10.1109/jphot.2023.3306806" @default.
- W4386025835 hasPublicationYear "2023" @default.
- W4386025835 type Work @default.
- W4386025835 citedByCount "0" @default.
- W4386025835 crossrefType "journal-article" @default.
- W4386025835 hasAuthorship W4386025835A5004820093 @default.
- W4386025835 hasAuthorship W4386025835A5065509814 @default.
- W4386025835 hasBestOaLocation W43860258351 @default.
- W4386025835 hasConcept C120665830 @default.
- W4386025835 hasConcept C121332964 @default.
- W4386025835 hasConcept C122041747 @default.
- W4386025835 hasConcept C134306372 @default.
- W4386025835 hasConcept C15336307 @default.
- W4386025835 hasConcept C154945302 @default.
- W4386025835 hasConcept C186370098 @default.
- W4386025835 hasConcept C191897082 @default.
- W4386025835 hasConcept C192562407 @default.
- W4386025835 hasConcept C2776032975 @default.
- W4386025835 hasConcept C33923547 @default.
- W4386025835 hasConcept C41008148 @default.
- W4386025835 hasConcept C519063684 @default.
- W4386025835 hasConcept C62520636 @default.
- W4386025835 hasConceptScore W4386025835C120665830 @default.
- W4386025835 hasConceptScore W4386025835C121332964 @default.
- W4386025835 hasConceptScore W4386025835C122041747 @default.
- W4386025835 hasConceptScore W4386025835C134306372 @default.
- W4386025835 hasConceptScore W4386025835C15336307 @default.
- W4386025835 hasConceptScore W4386025835C154945302 @default.
- W4386025835 hasConceptScore W4386025835C186370098 @default.
- W4386025835 hasConceptScore W4386025835C191897082 @default.
- W4386025835 hasConceptScore W4386025835C192562407 @default.
- W4386025835 hasConceptScore W4386025835C2776032975 @default.
- W4386025835 hasConceptScore W4386025835C33923547 @default.
- W4386025835 hasConceptScore W4386025835C41008148 @default.
- W4386025835 hasConceptScore W4386025835C519063684 @default.
- W4386025835 hasConceptScore W4386025835C62520636 @default.
- W4386025835 hasIssue "5" @default.
- W4386025835 hasLocation W43860258351 @default.
- W4386025835 hasOpenAccess W4386025835 @default.
- W4386025835 hasPrimaryLocation W43860258351 @default.
- W4386025835 hasRelatedWork W2004548795 @default.
- W4386025835 hasRelatedWork W2032039204 @default.
- W4386025835 hasRelatedWork W2059638863 @default.
- W4386025835 hasRelatedWork W2073682629 @default.
- W4386025835 hasRelatedWork W2083241965 @default.
- W4386025835 hasRelatedWork W2094759408 @default.
- W4386025835 hasRelatedWork W2124730083 @default.
- W4386025835 hasRelatedWork W2354263513 @default.
- W4386025835 hasRelatedWork W2967276674 @default.
- W4386025835 hasRelatedWork W1733196678 @default.
- W4386025835 hasVolume "15" @default.
- W4386025835 isParatext "false" @default.
- W4386025835 isRetracted "false" @default.
- W4386025835 workType "article" @default.