FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386041921> ?p ?o ?g. }

• W4386041921 endingPage "S52" @default.
• W4386041921 startingPage "S51" @default.
• W4386041921 abstract "COVID-19 has been shown to adversely affect multiple organ systems, yet little is known about its effect on perioperative complications after spine surgery or the optimal timing of surgery after an infection. The purpose of this study is to characterize the risk profile in patients undergoing spine surgery during multiple time windows following COVID-19 infection. Retrospective. The National COVID Cohort Collaborative (N3C), a database of 17.4 million persons with 6.9 million COVID-19 cases. It is the largest multicenter cohort of COVID-19 cases and controls nationwide. Venous thromboembolic events, sepsis, surgical site infection, acute kidney injury, 30-day mortality, and 1-year mortality. We queried the N3C database for patients undergoing lumbar spinal fusion surgery. Patients were stratified into those with an initial documented COVID-19 infection within three time periods: 0-2 weeks, 2-6 weeks, or 6-12 weeks prior to surgery. All analyses were performed in the N3C Data Enclave Palantir platform. A total of 39,594 patients who underwent lumbar spinal fusion procedures were included. Patients who underwent surgery within 2 weeks of their COVID-19 diagnosis had a significantly increased risk for venous thromboembolic events (OR 2.29, 95% CI 1.58 to 3.32), sepsis (OR 1.56, 95% CI 1.03 to 2.36), 30-day mortality (OR 5.55, 95% CI 3.53 to 8.71), and one-year mortality (OR 2.70, 95% CI 1.91 to 3.82) compared to patients who did not have a positive COVID test during the 90 days prior to surgery. There was no significant difference in the rates of acute kidney injury or surgical site infection. Patients undergoing surgery between 2 and 6 weeks or between 6 and 12 weeks from date of COVID-19 infection did not show significantly elevated rates of any complication analyzed. Patients undergoing lumbar spinal fusion surgery within 2 weeks from initial COVID-19 diagnosis are at increased risk for perioperative venous thromboembolic events and sepsis. This effect does not persist beyond 2 weeks, however, so it may be warranted to postpone nonurgent spine surgeries for at least 2 weeks following a COVID-19 infection or to consider a more aggressive VTE chemoprophylaxis regimen for urgent surgery in COVID-19 patients. This abstract does not discuss or include any applicable devices or drugs." @default.
• W4386041921 created "2023-08-22" @default.
• W4386041921 creator A5061962101 @default.
• W4386041921 creator A5062269443 @default.
• W4386041921 creator A5066617199 @default.
• W4386041921 creator A5082599578 @default.
• W4386041921 creator A5052755111 @default.
• W4386041921 date "2023-09-01" @default.
• W4386041921 modified "2023-10-09" @default.
• W4386041921 title "100. Increased risk for venous thromboembolic events in patients undergoing lumbar spinal fusion within two weeks of COVID-19 infection" @default.
• W4386041921 doi "https://doi.org/10.1016/j.spinee.2023.06.152" @default.
• W4386041921 hasPublicationYear "2023" @default.
• W4386041921 type Work @default.
• W4386041921 citedByCount "0" @default.
• W4386041921 crossrefType "journal-article" @default.
• W4386041921 hasAuthorship W4386041921A5052755111 @default.
• W4386041921 hasAuthorship W4386041921A5061962101 @default.
• W4386041921 hasAuthorship W4386041921A5062269443 @default.
• W4386041921 hasAuthorship W4386041921A5066617199 @default.
• W4386041921 hasAuthorship W4386041921A5082599578 @default.
• W4386041921 hasConcept C126322002 @default.
• W4386041921 hasConcept C141071460 @default.
• W4386041921 hasConcept C167135981 @default.
• W4386041921 hasConcept C201903717 @default.
• W4386041921 hasConcept C2778384902 @default.
• W4386041921 hasConcept C2780375110 @default.
• W4386041921 hasConcept C2780472472 @default.
• W4386041921 hasConcept C31174226 @default.
• W4386041921 hasConcept C44575665 @default.
• W4386041921 hasConcept C71924100 @default.
• W4386041921 hasConcept C72563966 @default.
• W4386041921 hasConceptScore W4386041921C126322002 @default.
• W4386041921 hasConceptScore W4386041921C141071460 @default.
• W4386041921 hasConceptScore W4386041921C167135981 @default.
• W4386041921 hasConceptScore W4386041921C201903717 @default.
• W4386041921 hasConceptScore W4386041921C2778384902 @default.
• W4386041921 hasConceptScore W4386041921C2780375110 @default.
• W4386041921 hasConceptScore W4386041921C2780472472 @default.
• W4386041921 hasConceptScore W4386041921C31174226 @default.
• W4386041921 hasConceptScore W4386041921C44575665 @default.
• W4386041921 hasConceptScore W4386041921C71924100 @default.
• W4386041921 hasConceptScore W4386041921C72563966 @default.
• W4386041921 hasIssue "9" @default.
• W4386041921 hasLocation W43860419211 @default.
• W4386041921 hasOpenAccess W4386041921 @default.
• W4386041921 hasPrimaryLocation W43860419211 @default.
• W4386041921 hasRelatedWork W1520457732 @default.
• W4386041921 hasRelatedWork W2832459556 @default.
• W4386041921 hasRelatedWork W2910674778 @default.
• W4386041921 hasRelatedWork W2985696135 @default.
• W4386041921 hasRelatedWork W3030236844 @default.
• W4386041921 hasRelatedWork W3182723595 @default.
• W4386041921 hasRelatedWork W3215560449 @default.
• W4386041921 hasRelatedWork W4206554178 @default.
• W4386041921 hasRelatedWork W4255354536 @default.
• W4386041921 hasRelatedWork W4286005445 @default.
• W4386041921 hasVolume "23" @default.
• W4386041921 isParatext "false" @default.
• W4386041921 isRetracted "false" @default.
• W4386041921 workType "article" @default.