Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386046299> ?p ?o ?g. }
- W4386046299 abstract "Sepsis-induced coagulopathy (SIC) is a life-threatening complication characterized by the systemic activation of coagulation in sepsis. The diagnostic criteria of SIC consist of three items, including Sequential Organ Failure Assessment (SOFA) score, platelet count, and prothrombin time (PT)-international normalized ratio (INR). SIC has a high prevalence and it can lead to a higher mortality rate and longer length of hospital and ICU stay. Thus, the early detection of SIC is extremely important. It is unfortunate that there is still no precise biomarker for early diagnosis and assessment of the prognosis of SIC. We reviewed the current literature and discovered that some potential biomarkers, such as soluble thrombomodulin (sTM), thrombin-antithrombin complex (TAT), tissue plasminogen activator-inhibitor complex (t-PAIC), α2-plasmin inhibitor-plasmin complex (PIC), C-type lectin-like receptor 2 (CLEC-2), neutrophil extracellular traps (NETs), prothrombin fragment 1.2 (F1.2), Angiopoietin-2 (Ang-2), plasminogen activator inhibitor-1 (PAI-1), and tissue inhibitor of metalloproteinase-1 (TIMP-1) may be useful for early diagnosis, evaluation, and prognosis of SIC. Early initiation of treatment without missing any therapeutic opportunities may improve SIC patients' prognosis. Further large-scale clinical studies are still needed to confirm the role of these biomarkers in the diagnosis and prognosis assessment of SIC." @default.
- W4386046299 created "2023-08-23" @default.
- W4386046299 creator A5002931072 @default.
- W4386046299 creator A5006044856 @default.
- W4386046299 creator A5024088330 @default.
- W4386046299 creator A5049091920 @default.
- W4386046299 creator A5070846571 @default.
- W4386046299 date "2023-01-01" @default.
- W4386046299 modified "2023-09-27" @default.
- W4386046299 title "Potential Biomarkers for Early Diagnosis, Evaluation, and Prognosis of Sepsis-Induced Coagulopathy" @default.
- W4386046299 cites W169291730 @default.
- W4386046299 cites W1758592134 @default.
- W4386046299 cites W18465970 @default.
- W4386046299 cites W1933241387 @default.
- W4386046299 cites W1960125823 @default.
- W4386046299 cites W1964062551 @default.
- W4386046299 cites W1982604681 @default.
- W4386046299 cites W1983705436 @default.
- W4386046299 cites W1984881453 @default.
- W4386046299 cites W1988769907 @default.
- W4386046299 cites W1997531518 @default.
- W4386046299 cites W2013996375 @default.
- W4386046299 cites W2025631144 @default.
- W4386046299 cites W2045819100 @default.
- W4386046299 cites W2046786121 @default.
- W4386046299 cites W2058134060 @default.
- W4386046299 cites W2063818108 @default.
- W4386046299 cites W2064693934 @default.
- W4386046299 cites W2078817520 @default.
- W4386046299 cites W2083556566 @default.
- W4386046299 cites W2104934425 @default.
- W4386046299 cites W2107625978 @default.
- W4386046299 cites W2109202106 @default.
- W4386046299 cites W2110041998 @default.
- W4386046299 cites W2112530169 @default.
- W4386046299 cites W2123824752 @default.
- W4386046299 cites W2132121238 @default.
- W4386046299 cites W2134923719 @default.
- W4386046299 cites W2144589352 @default.
- W4386046299 cites W2154518739 @default.
- W4386046299 cites W2158825633 @default.
- W4386046299 cites W2160660095 @default.
- W4386046299 cites W2162563935 @default.
- W4386046299 cites W2163754500 @default.
- W4386046299 cites W2174446313 @default.
- W4386046299 cites W2230650963 @default.
- W4386046299 cites W2280404143 @default.
- W4386046299 cites W2330679995 @default.
- W4386046299 cites W2335526311 @default.
- W4386046299 cites W2413356523 @default.
- W4386046299 cites W2518839345 @default.
- W4386046299 cites W2553300030 @default.
- W4386046299 cites W2589326429 @default.
- W4386046299 cites W2735817878 @default.
- W4386046299 cites W2745119542 @default.
- W4386046299 cites W2756678274 @default.
- W4386046299 cites W2761080716 @default.
- W4386046299 cites W2793400613 @default.
- W4386046299 cites W2799655571 @default.
- W4386046299 cites W2800122232 @default.
- W4386046299 cites W2847857789 @default.
- W4386046299 cites W2900588276 @default.
- W4386046299 cites W2945110568 @default.
- W4386046299 cites W2959928913 @default.
- W4386046299 cites W2969988825 @default.
- W4386046299 cites W3035338615 @default.
- W4386046299 cites W3047912505 @default.
- W4386046299 cites W3096816149 @default.
- W4386046299 cites W3121797438 @default.
- W4386046299 cites W3127410815 @default.
- W4386046299 cites W3167593711 @default.
- W4386046299 cites W3201177508 @default.
- W4386046299 cites W3202964273 @default.
- W4386046299 cites W3205910140 @default.
- W4386046299 cites W4210331666 @default.
- W4386046299 cites W4233597213 @default.
- W4386046299 cites W4282924012 @default.
- W4386046299 cites W4298148160 @default.
- W4386046299 cites W4315778660 @default.
- W4386046299 cites W4318219028 @default.
- W4386046299 cites W81909359 @default.
- W4386046299 doi "https://doi.org/10.1177/10760296231195089" @default.
- W4386046299 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37605466" @default.
- W4386046299 hasPublicationYear "2023" @default.
- W4386046299 type Work @default.
- W4386046299 citedByCount "0" @default.
- W4386046299 crossrefType "journal-article" @default.
- W4386046299 hasAuthorship W4386046299A5002931072 @default.
- W4386046299 hasAuthorship W4386046299A5006044856 @default.
- W4386046299 hasAuthorship W4386046299A5024088330 @default.
- W4386046299 hasAuthorship W4386046299A5049091920 @default.
- W4386046299 hasAuthorship W4386046299A5070846571 @default.
- W4386046299 hasBestOaLocation W43860462991 @default.
- W4386046299 hasConcept C126322002 @default.
- W4386046299 hasConcept C134897094 @default.
- W4386046299 hasConcept C201267052 @default.
- W4386046299 hasConcept C2776914184 @default.
- W4386046299 hasConcept C2777292125 @default.
- W4386046299 hasConcept C2778384902 @default.
- W4386046299 hasConcept C2778734968 @default.