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- W4386071253 abstract "Oral cancer is a major health issue, especially in India. It is one of the most common malignancies. Tobacco and alcohol are the most common causes of oral cancer which mostly has the propensity to involve the tongue or buccal mucosa. The present study was conducted to assess the margins of early oral squamous cell carcinoma intraoperatively. Smoking, alcohol and tobacco consumption were found to be high-risk factors for oral carcinoma and synergistically increase the risk manifold. The results of the frozen section and nal histopathological report of resected tumor margins were comparable in our study. Margin shrinkage is often overlooked in the head and neck and especially so in oral cancer resection. Often, in vivo adequate margin of resection transforms into close margin of resection upon removal hence it is prudent to excise a healthy cuff tissue measuring 1 cm. The most important predictor for the recurrence of the disease is the involvement of tumour margins of the resected specimen. One major limitation of the frozen section is that the entire margin of the resected tumour cannot be assessed during surgery. Only a few areas of the margin of the tumour is evaluated and the deeper areas cannot be assessed. It can hence lead to 'False negative' results thereby could lead to potentiated chances of local recurrence or treatment failure. To mitigate this inherent issue, surgeons need to be experienced in judging and directing the most obvious regions for Frozen analysis. The role of teamwork along with the pathology team couldn't be underestimated at any cost. To conclude frozen section is a reliable tool for margin assessment intraoperatively especially in early cases. Surgeon and pathologist experience would certainly assist in mitigating the risk of false negatives" @default.
- W4386071253 created "2023-08-23" @default.
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- W4386071253 date "2023-08-01" @default.
- W4386071253 modified "2023-09-25" @default.
- W4386071253 title "INTRAOPERATIVE MARGIN ASSESSMENT OF EARLY ORAL SQUAMOUS CELL CARCINOMA – A SINGLE-CENTRE STUDY" @default.
- W4386071253 doi "https://doi.org/10.36106/ijsr/9507018" @default.
- W4386071253 hasPublicationYear "2023" @default.
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