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- W4386074893 abstract "Hepatitis B virus (HBV) is a serious global health challenge with vaccination being the most effective preventive measure. However, several risk-factors may impact HBV vaccine immunogenicity. We aimed to evaluate the immunogenicity of the HBV vaccine. Participants’ socio-demographic data were obtained from medical records. Anti-HBs testing was performed. Descriptive and bivariate analyses were performed. Among 431 participants, 62.2% (n=268) were males. In all, 43.2% (n=186) had normal weight, 24.8% (n=107) were overweight, and 17.6% (n=76) had obesity. Seroconversion after 3-dose HBV vaccination was 74.7%. Participants with normal weight had higher seroprevalence (n=156/186, 83.9%), compared with those with overweight (n=72/107, 67.3%) or obesity (n=48/76, 63.2%) (Normal weight vs overweight: aOR=2.44, 95% CI:1.38-4.32 and normal weight vs obesity: aOR=2.97, 95% CI:1.61-5.47). BMI is an independent factor impairing the vaccine response. These findings urge for more tailored vaccination strategies with focus on higher risk populations." @default.
- W4386074893 created "2023-08-23" @default.
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- W4386074893 date "2023-12-01" @default.
- W4386074893 modified "2023-09-27" @default.
- W4386074893 title "Seroconversion of hepatitis B vaccine among patients from outpatient clinic in Georgia" @default.
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- W4386074893 doi "https://doi.org/10.1016/j.jvacx.2023.100375" @default.
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