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• W4386080732 abstract "The reconstruction of 3D cine-MRI is challenged by highly undersampled k-space data in each cine frame, due to the slow speed of MR signal acquisition. We proposed a machine learning-based framework, spatial and temporal implicit neural representation learning (STINR-MR), for accurate 3D cine-MRI reconstruction from highly undersampled data. STINR-MR used a joint reconstruction and deformable registration approach to address the ill-posed spatiotemporal reconstruction problem, by solving a reference-frame 3D MR image and a corresponding motion model which deforms the reference frame to each cine frame. The reference-frame image was reconstructed as a spatial implicit neural representation (INR) network, which learns the mapping from input 3D spatial coordinates to corresponding MR values. The dynamic motion model was constructed via a temporal INR, as well as basis deformation vector fields(DVFs) extracted from prior/onboard 4D-MRIs. The learned INR encodes input time points and outputs corresponding weighting factors to combine the basis DVFs into time-resolved motion fields. STINR-MR was evaluated using MR data simulated from the 4D extended cardiac-torso (XCAT) digital phantom and MR data acquired clinically from a healthy human subject. Its reconstruction accuracy was also compared with that of the model-based non-rigid motion estimation method (MR-MOTUS). STINR-MR can reconstruct 3D cine-MR images with high temporal (<100 ms) and spatial (3 mm) resolutions to accurately capture different irregular motion patterns. Compared with MR-MOTUS, STINR-MR consistently reconstructed images with better quality, fewer artifacts, and achieved superior tumor localization accuracy. STINR-MR provides a lightweight and efficient framework for accurate 3D cine-MRI reconstruction, and does not require external data for pre-training to avoid generalizability issues encountered in deep learning methods." @default.
• W4386080732 created "2023-08-23" @default.
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• W4386080732 date "2023-08-18" @default.
• W4386080732 modified "2023-10-18" @default.
• W4386080732 title "3D cine-magnetic resonance imaging using spatial and temporal implicit neural representation learning (STINR-MR)." @default.
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