Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386084118> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W4386084118 abstract "Sulfasalazine and pentoxifylline are co-prescribed together to treat psoriasis and pemphigus vulgaris. Sulfasalazine is anti-inflammatory, immunosuppressant and antibiotic drug. While, pentoxifylline is vasodilator and immunosuppressant. The spectra of the two drugs and plasma suffer from a severe overlap.This work aims to simultaneously determine sulfasalazine and pentoxifylline in their binary mixture and spiked human plasma by the assessment of the UV spectral data.Two model updated chemometric methods were established using principle component regression and partial least squares regression models. The two models were validated in accordance to the Food and Drug Administration guidelines for the bio-analysis and were applied for the determination of both drugs in synthetic mixtures or spiked human plasma.Good results of accuracy and precision were within the accepted limits. In addition, three different assessment methods were used to evaluate the environmental greenness of the proposed models.The two updated models are simple, rapid, sensitive and precise and could be easily applied in quality control laboratories for determination of sulfasalazine and pentoxifylline, without any preliminary separation steps or interference from plasma matrix.Two model updated chemometric models called principle component regression and partial least squares regression were established for determination of sulfasalazine and pentoxifylline in spiked human plasma using UV spectrophotometric data." @default.
- W4386084118 created "2023-08-24" @default.
- W4386084118 creator A5027917050 @default.
- W4386084118 creator A5035280551 @default.
- W4386084118 creator A5066483584 @default.
- W4386084118 creator A5067181644 @default.
- W4386084118 date "2023-08-23" @default.
- W4386084118 modified "2023-10-01" @default.
- W4386084118 title "Smart Multivariate Spectrophotometric Determination of Two Co-Administered Autoimmune Drugs; Sulfasalazine and Pentoxifylline; in Bulk and Spiked Human Plasma" @default.
- W4386084118 cites W1232566583 @default.
- W4386084118 cites W1984892781 @default.
- W4386084118 cites W1996842820 @default.
- W4386084118 cites W2012298247 @default.
- W4386084118 cites W2027189557 @default.
- W4386084118 cites W2027619293 @default.
- W4386084118 cites W2066246559 @default.
- W4386084118 cites W2116004009 @default.
- W4386084118 cites W2177188027 @default.
- W4386084118 cites W2220570975 @default.
- W4386084118 cites W2262286884 @default.
- W4386084118 cites W2731989114 @default.
- W4386084118 cites W2781931056 @default.
- W4386084118 cites W2966764805 @default.
- W4386084118 cites W3035028232 @default.
- W4386084118 cites W3092466733 @default.
- W4386084118 cites W3198931166 @default.
- W4386084118 cites W4214771917 @default.
- W4386084118 cites W4223653140 @default.
- W4386084118 cites W4243203121 @default.
- W4386084118 cites W4245005961 @default.
- W4386084118 cites W4300565850 @default.
- W4386084118 cites W4323535044 @default.
- W4386084118 doi "https://doi.org/10.1093/jaoacint/qsad097" @default.
- W4386084118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37610330" @default.
- W4386084118 hasPublicationYear "2023" @default.
- W4386084118 type Work @default.
- W4386084118 citedByCount "0" @default.
- W4386084118 crossrefType "journal-article" @default.
- W4386084118 hasAuthorship W4386084118A5027917050 @default.
- W4386084118 hasAuthorship W4386084118A5035280551 @default.
- W4386084118 hasAuthorship W4386084118A5066483584 @default.
- W4386084118 hasAuthorship W4386084118A5067181644 @default.
- W4386084118 hasConcept C105795698 @default.
- W4386084118 hasConcept C126322002 @default.
- W4386084118 hasConcept C185592680 @default.
- W4386084118 hasConcept C22354355 @default.
- W4386084118 hasConcept C2779134260 @default.
- W4386084118 hasConcept C2779383735 @default.
- W4386084118 hasConcept C2780404050 @default.
- W4386084118 hasConcept C2780479503 @default.
- W4386084118 hasConcept C33923547 @default.
- W4386084118 hasConcept C71924100 @default.
- W4386084118 hasConcept C98274493 @default.
- W4386084118 hasConceptScore W4386084118C105795698 @default.
- W4386084118 hasConceptScore W4386084118C126322002 @default.
- W4386084118 hasConceptScore W4386084118C185592680 @default.
- W4386084118 hasConceptScore W4386084118C22354355 @default.
- W4386084118 hasConceptScore W4386084118C2779134260 @default.
- W4386084118 hasConceptScore W4386084118C2779383735 @default.
- W4386084118 hasConceptScore W4386084118C2780404050 @default.
- W4386084118 hasConceptScore W4386084118C2780479503 @default.
- W4386084118 hasConceptScore W4386084118C33923547 @default.
- W4386084118 hasConceptScore W4386084118C71924100 @default.
- W4386084118 hasConceptScore W4386084118C98274493 @default.
- W4386084118 hasLocation W43860841181 @default.
- W4386084118 hasLocation W43860841182 @default.
- W4386084118 hasOpenAccess W4386084118 @default.
- W4386084118 hasPrimaryLocation W43860841181 @default.
- W4386084118 hasRelatedWork W1969927056 @default.
- W4386084118 hasRelatedWork W2027619293 @default.
- W4386084118 hasRelatedWork W2043141738 @default.
- W4386084118 hasRelatedWork W2055739060 @default.
- W4386084118 hasRelatedWork W2065722033 @default.
- W4386084118 hasRelatedWork W2080020952 @default.
- W4386084118 hasRelatedWork W2086926908 @default.
- W4386084118 hasRelatedWork W2299323062 @default.
- W4386084118 hasRelatedWork W2438089724 @default.
- W4386084118 hasRelatedWork W2586852613 @default.
- W4386084118 isParatext "false" @default.
- W4386084118 isRetracted "false" @default.
- W4386084118 workType "article" @default.