Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386086523> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4386086523 abstract "Conformational changes are observed in many enzymes, but their role in catalysis is highly controversial. Here we present a theoretical model that illustrates how rigid catalysts can be fundamentally limited and how a conformational change induced by substrate binding can overcome this limitation, ultimately enabling barrier-free catalysis. The model is deliberately minimal, but the principle it illustrates is general and consistent with unique features of proteins as well as with previous informal proposals to explain the superiority of enzymes over other classes of catalysts. Implementing the discriminative switch suggested by the model could help overcome limitations currently encountered in the design of artificial catalysts." @default.
- W4386086523 created "2023-08-24" @default.
- W4386086523 creator A5068503267 @default.
- W4386086523 date "2023-08-23" @default.
- W4386086523 modified "2023-09-25" @default.
- W4386086523 title "How Flexibility Can Enhance Catalysis" @default.
- W4386086523 cites W1542496341 @default.
- W4386086523 cites W1891806042 @default.
- W4386086523 cites W1968878655 @default.
- W4386086523 cites W1974579447 @default.
- W4386086523 cites W1987194133 @default.
- W4386086523 cites W1991630775 @default.
- W4386086523 cites W2010535494 @default.
- W4386086523 cites W2036186069 @default.
- W4386086523 cites W2071744391 @default.
- W4386086523 cites W2127362915 @default.
- W4386086523 cites W2142468563 @default.
- W4386086523 cites W2152572188 @default.
- W4386086523 cites W2329265014 @default.
- W4386086523 cites W2334047574 @default.
- W4386086523 cites W2341535801 @default.
- W4386086523 cites W2416922748 @default.
- W4386086523 cites W2463220226 @default.
- W4386086523 cites W2912594620 @default.
- W4386086523 cites W2947171186 @default.
- W4386086523 cites W2982215879 @default.
- W4386086523 cites W3003660925 @default.
- W4386086523 cites W4256616114 @default.
- W4386086523 cites W4281945460 @default.
- W4386086523 cites W4376621652 @default.
- W4386086523 cites W566353445 @default.
- W4386086523 doi "https://doi.org/10.1103/physrevlett.131.088401" @default.
- W4386086523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37683166" @default.
- W4386086523 hasPublicationYear "2023" @default.
- W4386086523 type Work @default.
- W4386086523 citedByCount "0" @default.
- W4386086523 crossrefType "journal-article" @default.
- W4386086523 hasAuthorship W4386086523A5068503267 @default.
- W4386086523 hasConcept C105795698 @default.
- W4386086523 hasConcept C127413603 @default.
- W4386086523 hasConcept C161790260 @default.
- W4386086523 hasConcept C171250308 @default.
- W4386086523 hasConcept C178790620 @default.
- W4386086523 hasConcept C183696295 @default.
- W4386086523 hasConcept C185592680 @default.
- W4386086523 hasConcept C18903297 @default.
- W4386086523 hasConcept C192562407 @default.
- W4386086523 hasConcept C2777289219 @default.
- W4386086523 hasConcept C2777339483 @default.
- W4386086523 hasConcept C2780598303 @default.
- W4386086523 hasConcept C33923547 @default.
- W4386086523 hasConcept C41008148 @default.
- W4386086523 hasConcept C69118441 @default.
- W4386086523 hasConcept C71240020 @default.
- W4386086523 hasConcept C86803240 @default.
- W4386086523 hasConceptScore W4386086523C105795698 @default.
- W4386086523 hasConceptScore W4386086523C127413603 @default.
- W4386086523 hasConceptScore W4386086523C161790260 @default.
- W4386086523 hasConceptScore W4386086523C171250308 @default.
- W4386086523 hasConceptScore W4386086523C178790620 @default.
- W4386086523 hasConceptScore W4386086523C183696295 @default.
- W4386086523 hasConceptScore W4386086523C185592680 @default.
- W4386086523 hasConceptScore W4386086523C18903297 @default.
- W4386086523 hasConceptScore W4386086523C192562407 @default.
- W4386086523 hasConceptScore W4386086523C2777289219 @default.
- W4386086523 hasConceptScore W4386086523C2777339483 @default.
- W4386086523 hasConceptScore W4386086523C2780598303 @default.
- W4386086523 hasConceptScore W4386086523C33923547 @default.
- W4386086523 hasConceptScore W4386086523C41008148 @default.
- W4386086523 hasConceptScore W4386086523C69118441 @default.
- W4386086523 hasConceptScore W4386086523C71240020 @default.
- W4386086523 hasConceptScore W4386086523C86803240 @default.
- W4386086523 hasFunder F4320320883 @default.
- W4386086523 hasIssue "8" @default.
- W4386086523 hasLocation W43860865231 @default.
- W4386086523 hasLocation W43860865232 @default.
- W4386086523 hasOpenAccess W4386086523 @default.
- W4386086523 hasPrimaryLocation W43860865231 @default.
- W4386086523 hasRelatedWork W1598587668 @default.
- W4386086523 hasRelatedWork W2075675703 @default.
- W4386086523 hasRelatedWork W2146194886 @default.
- W4386086523 hasRelatedWork W2170478559 @default.
- W4386086523 hasRelatedWork W2557732718 @default.
- W4386086523 hasRelatedWork W2592531136 @default.
- W4386086523 hasRelatedWork W2748952813 @default.
- W4386086523 hasRelatedWork W2753730701 @default.
- W4386086523 hasRelatedWork W2899084033 @default.
- W4386086523 hasRelatedWork W2962753830 @default.
- W4386086523 hasVolume "131" @default.
- W4386086523 isParatext "false" @default.
- W4386086523 isRetracted "false" @default.
- W4386086523 workType "article" @default.