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- W4386087269 abstract "The aims of this study were to: (1) evaluate potential associations between genetic traits, postpartum phenotypes, cow factors and postpartum vaginal discharge score (VDS); and (2) investigate possible associations between postpartum VDS, plasma progesterone (P4) after first service and reproductive performance. First and second parity (n = 2,842) spring-calving lactating dairy cows from 35 dairy herds were enrolled. Farm visits were performed every 2 wk during the postpartum and weekly during the breeding period. Cows that were at wk 3 and wk 7 postpartum and between 7 and 13 d after the first AI were examined. Body condition score (BCS) was measured on all farm visits using a 1 to 5 scale [low (≤2.5), target (≥2.75)]. Transrectal ultrasound examinations were conducted to determine the presence or absence of a corpus luteum (CL). Vaginal discharge score was determined at wk 3 and wk 7 using a Metricheck device and utilizing a 1 to 4 scale [1 = clear mucus; 4 = mucopurulent with > 50% purulent material ± odour]. At wk 3, cows having a VDS ≤2 were considered to have normal reproductive tract health status (RTHS). At wk7, cows having a VDS = 1 were considered to have normal RTHS. Blood samples were collected at each visit, and plasma concentrations of glucose, β-hydroxybutyrate, fatty acids and progesterone (only during breeding visit) were analyzed. Animals with target BCS at wk 3 and wk 7 had greater odds of having normal RTHS at wk 3 and wk 7, respectively, than cows with low BCS. Cows with a CL at wk 3 and wk 7 had greater prevalence of normal RTHS at wk 3 and wk 7, respectively, compared with cows without a CL. Cows with normal RTHS had a lesser plasma concentration of β-hydroxybutyrate at wk 3 and wk 7 and greater plasma concentration of glucose at wk 3 compared with animals with abnormal RTHS. More cows in the greatest quartiles for the fertility sub-index of the Economic Breeding Index and genetic merit for milk production traits [milk kg and milk protein (%)] had normal RTHS at wk 3 and wk 7 compared with the other quartiles. Cows with a VDS score = 4 at wk 7 postpartum had lesser plasma P4 concentration after first AI (−1.2, −1.1 and −1.0 ng/mL compared with cows with VDS = 1, 2, and 3, respectively). Similarly, cows with VDS score = 4 at both wk 3 and wk 7 had lesser pregnancy at first service, lesser cumulative pregnancy rates at wk 3-, 6- and 12 during the breeding period, and longer mating start date to conception interval (+3 d if VDS = 4 at wk 3; + 5 d if VDS = 4 at wk 7) compared with cows having other VDS scores. In conclusion, cows with superior genetic merit for fertility traits and milk production traits, favorable fertility phenotypes at wk 3 and wk 7 were all associated with greater likelihood of having normal RTHS. In turn, abnormal postpartum RTHS and greater postpartum VDS (score = 4) were associated with lesser odds of successful pregnancy establishment." @default.
- W4386087269 created "2023-08-24" @default.
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- W4386087269 date "2023-08-01" @default.
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- W4386087269 title "Postpartum vaginal discharge score is associated with genetic traits, postpartum fertility phenotypes, metabolic status and overall reproductive performance in seasonal-calving pasture-based dairy cows" @default.
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- W4386087269 doi "https://doi.org/10.3168/jds.2023-23324" @default.
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