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- W4386092023 abstract "Macrophage-derived chemokine (MDC/CCL22) is a chemokine of the C-C subfamily. It is involved in T-cellular maturation and migration. Our previous research shows that plasma CCL22/MDC tends to show a statistically significant depletion of concentrations in acute patients and convalescents when compared to healthy donors. In the current work, we investigate existing views on MDC/CCL22 dynamics in association with various pathologies, including respiratory diseases and, specifically, COVID-19. Additionally, we present our explanations for the observed decrease in MDC/CCL22 concentrations in COVID-19. The first hypothesis we provide implies that viral products bind to MDC/CCL22 and block its activity. Another explanation for this phenomenon is based on dendritic cells population and the inhibition of their function." @default.
- W4386092023 created "2023-08-24" @default.
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- W4386092023 date "2023-08-23" @default.
- W4386092023 modified "2023-09-29" @default.
- W4386092023 title "Macrophage-Derived Chemokine MDC/CCL22: An Ambiguous Finding in COVID-19" @default.
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- W4386092023 doi "https://doi.org/10.3390/ijms241713083" @default.
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