FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386093589> ?p ?o ?g. }

• W4386093589 abstract "DNA damage and repair play a crucial role in the development, progression and treatment of cancer. In response to various types of DNA damage, the organism initiates a series of DNA damage responses that trigger post‑DNA damage repair processes. Among the most severe forms of DNA damage are DNA double‑strand breaks (DSBs), which can be repaired by the body through two pathways: Homologous recombination and non‑homologous end joining. The repair of DNA damage, particularly DNA DSBs, significantly influences the sensitivity and resistance of cancer cells to chemotherapy and radiotherapy. Numerous studies have demonstrated that long non‑coding RNAs (lncRNAs) can exert multiple regulatory effects on cancer cells by binding to RNA binding proteins (RBPs), thereby influencing DNA damage repair. Based on a comprehensive literature search, the existing research on the regulation of DNA damage repair by lncRNAs interacting with RBPs has primarily focused on the repair of DNA DSBs. Therefore, the present review discusses the regulatory effects of the interaction between lncRNAs and RBPs on DNA damage repair in cancer cells, with a specific focus on the repair of DNA DSBs and its implications in cancer. It is hoped that comprehensive analysis may enhance the current understanding of the molecular mechanisms underlying DNA damage repair in cancer and may lead to the identification of novel diagnostic biomarkers and potential therapeutic targets." @default.
• W4386093589 created "2023-08-24" @default.
• W4386093589 creator A5032981233 @default.
• W4386093589 creator A5068573415 @default.
• W4386093589 creator A5071653476 @default.
• W4386093589 date "2023-08-23" @default.
• W4386093589 modified "2023-10-01" @default.
• W4386093589 title "Advances in the role of long non‑coding RNAs and RNA‑binding proteins in regulating DNA damage repair in cancer cells" @default.
• W4386093589 cites W1843014747 @default.
• W4386093589 cites W1965086052 @default.
• W4386093589 cites W1965531809 @default.
• W4386093589 cites W1967630574 @default.
• W4386093589 cites W1971419576 @default.
• W4386093589 cites W1975548607 @default.
• W4386093589 cites W1988280121 @default.
• W4386093589 cites W2002255627 @default.
• W4386093589 cites W2008181290 @default.
• W4386093589 cites W2008396969 @default.
• W4386093589 cites W2010677667 @default.
• W4386093589 cites W2017844161 @default.
• W4386093589 cites W2045526190 @default.
• W4386093589 cites W2052039819 @default.
• W4386093589 cites W2052801384 @default.
• W4386093589 cites W2062154047 @default.
• W4386093589 cites W2062779626 @default.
• W4386093589 cites W2065022250 @default.
• W4386093589 cites W2067328670 @default.
• W4386093589 cites W2067466498 @default.
• W4386093589 cites W2071462293 @default.
• W4386093589 cites W2073946370 @default.
• W4386093589 cites W2074730941 @default.
• W4386093589 cites W2077436902 @default.
• W4386093589 cites W2081630196 @default.
• W4386093589 cites W2085302194 @default.
• W4386093589 cites W2086641857 @default.
• W4386093589 cites W2090408878 @default.
• W4386093589 cites W2093814864 @default.
• W4386093589 cites W2102752109 @default.
• W4386093589 cites W2102839588 @default.
• W4386093589 cites W2102968159 @default.
• W4386093589 cites W2104003823 @default.
• W4386093589 cites W2106861716 @default.
• W4386093589 cites W2107739085 @default.
• W4386093589 cites W2109716976 @default.
• W4386093589 cites W2109879947 @default.
• W4386093589 cites W2110817748 @default.
• W4386093589 cites W2111772438 @default.
• W4386093589 cites W2117513720 @default.
• W4386093589 cites W2130835129 @default.
• W4386093589 cites W2132334809 @default.
• W4386093589 cites W2133959309 @default.
• W4386093589 cites W2137840425 @default.
• W4386093589 cites W2139022223 @default.
• W4386093589 cites W2141337702 @default.
• W4386093589 cites W2142125232 @default.
• W4386093589 cites W2144137532 @default.
• W4386093589 cites W2145200068 @default.
• W4386093589 cites W2145583284 @default.
• W4386093589 cites W2146204567 @default.
• W4386093589 cites W2151252396 @default.
• W4386093589 cites W2152154355 @default.
• W4386093589 cites W2152886258 @default.
• W4386093589 cites W2153466677 @default.
• W4386093589 cites W2155318349 @default.
• W4386093589 cites W2157132094 @default.
• W4386093589 cites W2157899948 @default.
• W4386093589 cites W2161280732 @default.
• W4386093589 cites W2162547088 @default.
• W4386093589 cites W2169741450 @default.
• W4386093589 cites W2173456459 @default.
• W4386093589 cites W2174181728 @default.
• W4386093589 cites W2212776653 @default.
• W4386093589 cites W2341032293 @default.
• W4386093589 cites W2343471288 @default.
• W4386093589 cites W2344125613 @default.
• W4386093589 cites W2407531000 @default.
• W4386093589 cites W2411866449 @default.
• W4386093589 cites W2471389521 @default.
• W4386093589 cites W2515458810 @default.
• W4386093589 cites W2525843044 @default.
• W4386093589 cites W2560374068 @default.
• W4386093589 cites W2564052675 @default.
• W4386093589 cites W2613061578 @default.
• W4386093589 cites W2759838829 @default.
• W4386093589 cites W2765241643 @default.
• W4386093589 cites W2771049305 @default.
• W4386093589 cites W2774050434 @default.
• W4386093589 cites W2783113646 @default.
• W4386093589 cites W2787142790 @default.
• W4386093589 cites W2789794079 @default.
• W4386093589 cites W2789891087 @default.
• W4386093589 cites W2791555520 @default.
• W4386093589 cites W2794429875 @default.
• W4386093589 cites W2801246231 @default.
• W4386093589 cites W2803631610 @default.
• W4386093589 cites W2803782006 @default.
• W4386093589 cites W2884234556 @default.
• W4386093589 cites W2898088739 @default.
• W4386093589 cites W2901274238 @default.
• W4386093589 cites W2943588752 @default.

• next