Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386095495> ?p ?o ?g. }
- W4386095495 abstract "Abstract We enable microelectronic devices to interrogate biology’s molecular communication, perform computations, and in real time control biological systems, including at several hierarchical levels: proteins, cells, and cell consortia. A key driver is establishing electronic access to and from biology’s native redox networks. First, redox-mediated electro-biofabrication facilitates facile assembly of biological components onto microelectronic systems, then electrode-actuated redox allows digital programming of enzyme activity, and further, redox-mediated electrogenetics facilitates closed-loop electronic control of cellular function. Specifically, we show algorithm-based feedback control of enzyme activity, cellular genetic circuits (via eCRISPR) and cell consortia behavior, all enabled by electronic data transfer. We further demonstrate electronic switching of cell-cell quorum sensing communication from one autoinducer network to another, creating an electronically controlled “bilingual” cell. We suggest these methodologies will not only help us to better understand biological systems, but design and control those currently unimagined." @default.
- W4386095495 created "2023-08-24" @default.
- W4386095495 creator A5002058484 @default.
- W4386095495 creator A5003445858 @default.
- W4386095495 creator A5012854282 @default.
- W4386095495 creator A5027095675 @default.
- W4386095495 creator A5036359331 @default.
- W4386095495 creator A5047227203 @default.
- W4386095495 creator A5062395963 @default.
- W4386095495 creator A5065876635 @default.
- W4386095495 creator A5072686970 @default.
- W4386095495 creator A5087392135 @default.
- W4386095495 date "2023-08-22" @default.
- W4386095495 modified "2023-09-23" @default.
- W4386095495 title "Redox-enabled Electronic Interrogation and Feedback Control of Hierarchical and Networked Biological Systems" @default.
- W4386095495 cites W1222149878 @default.
- W4386095495 cites W1521502403 @default.
- W4386095495 cites W1972435034 @default.
- W4386095495 cites W1996135784 @default.
- W4386095495 cites W2004465286 @default.
- W4386095495 cites W2039771621 @default.
- W4386095495 cites W2045589130 @default.
- W4386095495 cites W2051692881 @default.
- W4386095495 cites W2058930537 @default.
- W4386095495 cites W2064164664 @default.
- W4386095495 cites W2083489645 @default.
- W4386095495 cites W2090744083 @default.
- W4386095495 cites W2099090468 @default.
- W4386095495 cites W2108282512 @default.
- W4386095495 cites W2120503144 @default.
- W4386095495 cites W2120932131 @default.
- W4386095495 cites W2122373851 @default.
- W4386095495 cites W2147203051 @default.
- W4386095495 cites W2148325536 @default.
- W4386095495 cites W2169061810 @default.
- W4386095495 cites W2169244146 @default.
- W4386095495 cites W2294690275 @default.
- W4386095495 cites W2298762068 @default.
- W4386095495 cites W2345099907 @default.
- W4386095495 cites W2430232674 @default.
- W4386095495 cites W2462904652 @default.
- W4386095495 cites W2507618556 @default.
- W4386095495 cites W2575126330 @default.
- W4386095495 cites W2765183388 @default.
- W4386095495 cites W2802855191 @default.
- W4386095495 cites W2897051424 @default.
- W4386095495 cites W2897756564 @default.
- W4386095495 cites W2924405297 @default.
- W4386095495 cites W2946641322 @default.
- W4386095495 cites W2954398758 @default.
- W4386095495 cites W2969353819 @default.
- W4386095495 cites W2978355872 @default.
- W4386095495 cites W2988139359 @default.
- W4386095495 cites W2990541668 @default.
- W4386095495 cites W3010291540 @default.
- W4386095495 cites W3012140048 @default.
- W4386095495 cites W3025262723 @default.
- W4386095495 cites W3030627391 @default.
- W4386095495 cites W3034117866 @default.
- W4386095495 cites W3083888592 @default.
- W4386095495 cites W3084098393 @default.
- W4386095495 cites W3094330590 @default.
- W4386095495 cites W3121270108 @default.
- W4386095495 cites W3122133550 @default.
- W4386095495 cites W3141090209 @default.
- W4386095495 cites W3148352910 @default.
- W4386095495 cites W3154859673 @default.
- W4386095495 cites W3156825303 @default.
- W4386095495 cites W3172312536 @default.
- W4386095495 cites W3172932458 @default.
- W4386095495 cites W3191356595 @default.
- W4386095495 cites W3206372741 @default.
- W4386095495 cites W3208809595 @default.
- W4386095495 cites W4210630329 @default.
- W4386095495 cites W4229002972 @default.
- W4386095495 cites W4283731082 @default.
- W4386095495 cites W4288692499 @default.
- W4386095495 cites W4291950870 @default.
- W4386095495 cites W4295960860 @default.
- W4386095495 cites W4307931493 @default.
- W4386095495 cites W4311362382 @default.
- W4386095495 cites W4318460301 @default.
- W4386095495 cites W4319812475 @default.
- W4386095495 cites W4375853957 @default.
- W4386095495 doi "https://doi.org/10.1101/2023.08.22.554301" @default.
- W4386095495 hasPublicationYear "2023" @default.
- W4386095495 type Work @default.
- W4386095495 citedByCount "0" @default.
- W4386095495 crossrefType "posted-content" @default.
- W4386095495 hasAuthorship W4386095495A5002058484 @default.
- W4386095495 hasAuthorship W4386095495A5003445858 @default.
- W4386095495 hasAuthorship W4386095495A5012854282 @default.
- W4386095495 hasAuthorship W4386095495A5027095675 @default.
- W4386095495 hasAuthorship W4386095495A5036359331 @default.
- W4386095495 hasAuthorship W4386095495A5047227203 @default.
- W4386095495 hasAuthorship W4386095495A5062395963 @default.
- W4386095495 hasAuthorship W4386095495A5065876635 @default.
- W4386095495 hasAuthorship W4386095495A5072686970 @default.
- W4386095495 hasAuthorship W4386095495A5087392135 @default.
- W4386095495 hasBestOaLocation W43860954951 @default.