Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386099306> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4386099306 endingPage "113" @default.
- W4386099306 startingPage "105" @default.
- W4386099306 abstract "Aims: Along with the bone loss due to aging and postmenopausal osteoporosis (PMO) is the muscle mass loss, with an increasing occurrence of poorer body composition and osteosarcopenia. The current pharmacological recommendation guidelines for PMO treatment does not include any drugs that promote muscle hypertrophy. Nandrolone Decanoate (ND) is an anabolic steroid that has proven to increase bone and muscle mass in several pathologic conditions. Thus, we aimed to search for studing with body composition measurements, especially lean body mass, in postmenopausal women undergoing pharmacological treatment with ND for PMO.
 Study Design: Review with systematic search strategy.
 Methodology: We used free and structured MeSh terms combined in a PICO strategy, searching for studies in PubMed, CENTRAL, LILACS, Scielo, Open Grey, and TRIP database.
 Results: Three studies were found and included for analysis, two of which were randomized controlled and one observational. All studies observed positive increments in muscle mass concomitant with an increase in bone mass, and a reduction in body fat mass, due to the treatment of PMO with ND. Side effects were predominantly androgenic (voice deepening, increased hirsutism), considered mild, well tolerated, and without serious adverse events.
 Conclusion: ND was an effective drug for increasing lean body mass, reduce body fat, concomitantly improving several bone health parameters (bone mineral content and density) and outcomes (fractures), showing adequate clinical safety, therefore becoming a potential adjuvant to be considered in the medical therapeutic armamentarium for optimized PMO treatment." @default.
- W4386099306 created "2023-08-24" @default.
- W4386099306 creator A5002883562 @default.
- W4386099306 creator A5023830488 @default.
- W4386099306 creator A5079295112 @default.
- W4386099306 creator A5092680986 @default.
- W4386099306 creator A5092680987 @default.
- W4386099306 date "2023-08-23" @default.
- W4386099306 modified "2023-10-05" @default.
- W4386099306 title "Lean Body Mass in Osteoporotic Postmenopausal Women Treated with Nandrolone Decanoate: A Systematic Search Review" @default.
- W4386099306 doi "https://doi.org/10.9734/jammr/2023/v35i205179" @default.
- W4386099306 hasPublicationYear "2023" @default.
- W4386099306 type Work @default.
- W4386099306 citedByCount "0" @default.
- W4386099306 crossrefType "journal-article" @default.
- W4386099306 hasAuthorship W4386099306A5002883562 @default.
- W4386099306 hasAuthorship W4386099306A5023830488 @default.
- W4386099306 hasAuthorship W4386099306A5079295112 @default.
- W4386099306 hasAuthorship W4386099306A5092680986 @default.
- W4386099306 hasAuthorship W4386099306A5092680987 @default.
- W4386099306 hasBestOaLocation W43860993061 @default.
- W4386099306 hasConcept C1008401 @default.
- W4386099306 hasConcept C120863210 @default.
- W4386099306 hasConcept C126322002 @default.
- W4386099306 hasConcept C126894567 @default.
- W4386099306 hasConcept C134018914 @default.
- W4386099306 hasConcept C147583825 @default.
- W4386099306 hasConcept C197934379 @default.
- W4386099306 hasConcept C2776541429 @default.
- W4386099306 hasConcept C2776886416 @default.
- W4386099306 hasConcept C2779480814 @default.
- W4386099306 hasConcept C2779929075 @default.
- W4386099306 hasConcept C2780816001 @default.
- W4386099306 hasConcept C71924100 @default.
- W4386099306 hasConceptScore W4386099306C1008401 @default.
- W4386099306 hasConceptScore W4386099306C120863210 @default.
- W4386099306 hasConceptScore W4386099306C126322002 @default.
- W4386099306 hasConceptScore W4386099306C126894567 @default.
- W4386099306 hasConceptScore W4386099306C134018914 @default.
- W4386099306 hasConceptScore W4386099306C147583825 @default.
- W4386099306 hasConceptScore W4386099306C197934379 @default.
- W4386099306 hasConceptScore W4386099306C2776541429 @default.
- W4386099306 hasConceptScore W4386099306C2776886416 @default.
- W4386099306 hasConceptScore W4386099306C2779480814 @default.
- W4386099306 hasConceptScore W4386099306C2779929075 @default.
- W4386099306 hasConceptScore W4386099306C2780816001 @default.
- W4386099306 hasConceptScore W4386099306C71924100 @default.
- W4386099306 hasIssue "20" @default.
- W4386099306 hasLocation W43860993061 @default.
- W4386099306 hasOpenAccess W4386099306 @default.
- W4386099306 hasPrimaryLocation W43860993061 @default.
- W4386099306 hasRelatedWork W1968380023 @default.
- W4386099306 hasRelatedWork W1970861121 @default.
- W4386099306 hasRelatedWork W2005086919 @default.
- W4386099306 hasRelatedWork W2033313326 @default.
- W4386099306 hasRelatedWork W2044054235 @default.
- W4386099306 hasRelatedWork W2086824124 @default.
- W4386099306 hasRelatedWork W2098693342 @default.
- W4386099306 hasRelatedWork W2135465135 @default.
- W4386099306 hasRelatedWork W2151025762 @default.
- W4386099306 hasRelatedWork W2168702221 @default.
- W4386099306 hasVolume "35" @default.
- W4386099306 isParatext "false" @default.
- W4386099306 isRetracted "false" @default.
- W4386099306 workType "article" @default.