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- W4386128528 abstract "Metabolic theories for the origin of life suggest that the first step was the onset of a self-organized reaction network bearing similarities to the core of biological metabolism. Among the most important biological pathways in this regard are the transamination and reductive amination reactions that convert keto acids into amino acids, the building blocks of all proteins and enzymes. In this chapter, we discuss the nonenzymatic versions of these two reactions that occur in water and examine efforts to understand their chemical mechanisms. The chemical insights obtained in this way help to understand the fundamental principles of biochemistry and shed light on the conditions under which these pathways might have emerged at the origin of life." @default.
- W4386128528 created "2023-08-25" @default.
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- W4386128528 date "2023-01-01" @default.
- W4386128528 modified "2023-10-18" @default.
- W4386128528 title "Mechanism and catalysis of nonenzymatic analogs of amino acid biosynthesis" @default.
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- W4386128528 doi "https://doi.org/10.1016/bs.apoc.2023.07.001" @default.
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