FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386133921> ?p ?o ?g. }

• W4386133921 endingPage "e0000915" @default.
• W4386133921 startingPage "e0000915" @default.
• W4386133921 abstract "Maternal pneumococcal vaccines have been proposed as a method of protecting infants in the first few months of life. In this paper, we use results from a dynamic transmission model to assess the cost-effectiveness of a maternal pneumococcal polysaccharide vaccine from both healthcare and societal perspectives. We estimate the costs of delivering a maternal pneumococcal polysaccharide vaccine, the healthcare costs averted, and productivity losses avoided through the prevention of severe pneumococcal outcomes such as pneumonia and meningitis. Our model estimates that a maternal pneumococcal program would cost $606 (2020 USD, 95% prediction interval 437 to 779) from a healthcare perspective and $132 (95% prediction interval -1 to 265) from a societal perspective per DALY averted for one year of vaccine delivery. Hence, a maternal pneumococcal vaccine would be cost-effective from a societal perspective but not cost-effective from a healthcare perspective using Sierra Leone’s GDP per capita of $527 as a cost-effectiveness threshold. Sensitivity analysis demonstrates how the choice to discount ongoing health benefits determines whether the maternal pneumococcal vaccine was deemed cost-effective from a healthcare perspective. Without discounting, the cost per DALY averted would be $292 (55% of Sierra Leone’s GDP per capita) from a healthcare perspective. Further, the cost per DALY averted would be $142 (27% GDP per capita) from a healthcare perspective if PPV could be procured at the same cost relative to PCV in Sierra Leone as on the PAHO reference price list. Overall, our paper demonstrates that maternal pneumococcal vaccines have the potential to be cost-effective in low-income settings; however, the likelihood of low-income countries self-financing this intervention will depend on negotiations with vaccine providers on vaccine price. Vaccine price is the largest program cost driving the cost-effectiveness of a future maternal pneumococcal vaccine." @default.
• W4386133921 created "2023-08-25" @default.
• W4386133921 creator A5034817202 @default.
• W4386133921 creator A5043353916 @default.
• W4386133921 creator A5053264166 @default.
• W4386133921 creator A5080696336 @default.
• W4386133921 date "2023-08-24" @default.
• W4386133921 modified "2023-09-27" @default.
• W4386133921 title "Cost-effectiveness analysis of a maternal pneumococcal vaccine in low-income, high-burden settings such as Sierra Leone" @default.
• W4386133921 cites W1776326632 @default.
• W4386133921 cites W1913653529 @default.
• W4386133921 cites W1949787710 @default.
• W4386133921 cites W2015651881 @default.
• W4386133921 cites W2018126167 @default.
• W4386133921 cites W2037336197 @default.
• W4386133921 cites W2051967926 @default.
• W4386133921 cites W2128580255 @default.
• W4386133921 cites W2135371370 @default.
• W4386133921 cites W2169339716 @default.
• W4386133921 cites W2169729911 @default.
• W4386133921 cites W2169875910 @default.
• W4386133921 cites W2557867537 @default.
• W4386133921 cites W2734827844 @default.
• W4386133921 cites W2751884637 @default.
• W4386133921 cites W2761318636 @default.
• W4386133921 cites W2783247289 @default.
• W4386133921 cites W2808668519 @default.
• W4386133921 cites W2901989937 @default.
• W4386133921 cites W2904560398 @default.
• W4386133921 cites W2936439923 @default.
• W4386133921 cites W2950197636 @default.
• W4386133921 cites W2965037752 @default.
• W4386133921 cites W2966037854 @default.
• W4386133921 cites W2968830442 @default.
• W4386133921 cites W2991330128 @default.
• W4386133921 cites W3003678805 @default.
• W4386133921 cites W3035778484 @default.
• W4386133921 cites W3045152699 @default.
• W4386133921 cites W3046399222 @default.
• W4386133921 cites W3047866258 @default.
• W4386133921 cites W3083955261 @default.
• W4386133921 cites W3095534716 @default.
• W4386133921 cites W3174905800 @default.
• W4386133921 cites W4281740425 @default.
• W4386133921 doi "https://doi.org/10.1371/journal.pgph.0000915" @default.
• W4386133921 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37619237" @default.
• W4386133921 hasPublicationYear "2023" @default.
• W4386133921 type Work @default.
• W4386133921 citedByCount "0" @default.
• W4386133921 crossrefType "journal-article" @default.
• W4386133921 hasAuthorship W4386133921A5034817202 @default.
• W4386133921 hasAuthorship W4386133921A5043353916 @default.
• W4386133921 hasAuthorship W4386133921A5053264166 @default.
• W4386133921 hasAuthorship W4386133921A5080696336 @default.
• W4386133921 hasBestOaLocation W43861339211 @default.
• W4386133921 hasConcept C127598652 @default.
• W4386133921 hasConcept C162324750 @default.
• W4386133921 hasConcept C2908647359 @default.
• W4386133921 hasConcept C3018567284 @default.
• W4386133921 hasConcept C45355965 @default.
• W4386133921 hasConcept C71924100 @default.
• W4386133921 hasConcept C99454951 @default.
• W4386133921 hasConceptScore W4386133921C127598652 @default.
• W4386133921 hasConceptScore W4386133921C162324750 @default.
• W4386133921 hasConceptScore W4386133921C2908647359 @default.
• W4386133921 hasConceptScore W4386133921C3018567284 @default.
• W4386133921 hasConceptScore W4386133921C45355965 @default.
• W4386133921 hasConceptScore W4386133921C71924100 @default.
• W4386133921 hasConceptScore W4386133921C99454951 @default.
• W4386133921 hasIssue "8" @default.
• W4386133921 hasLocation W43861339211 @default.
• W4386133921 hasLocation W43861339212 @default.
• W4386133921 hasOpenAccess W4386133921 @default.
• W4386133921 hasPrimaryLocation W43861339211 @default.
• W4386133921 hasRelatedWork W1988546241 @default.
• W4386133921 hasRelatedWork W2002909381 @default.
• W4386133921 hasRelatedWork W2009120897 @default.
• W4386133921 hasRelatedWork W2148695867 @default.
• W4386133921 hasRelatedWork W2398160223 @default.
• W4386133921 hasRelatedWork W2792823055 @default.
• W4386133921 hasRelatedWork W2994539721 @default.
• W4386133921 hasRelatedWork W2999887050 @default.
• W4386133921 hasRelatedWork W3105496498 @default.
• W4386133921 hasRelatedWork W4297129717 @default.
• W4386133921 hasVolume "3" @default.
• W4386133921 isParatext "false" @default.
• W4386133921 isRetracted "false" @default.
• W4386133921 workType "article" @default.