FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386162745> ?p ?o ?g. }

• W4386162745 abstract "Abstract Background Cancers are as common in individuals with intellectual disabilities as in the general population (GP). For the subgroup of people with profound and multiple disabilities (PMD) who present with both severe intellectual disability and major motor disorders, the frequency and distribution of cancers are currently not known, preventing proper cancer surveillance. Methods We carried out a systematic and synthetic review of the medical literature, including a focused search of Japanese data. Results The total risk of cancer in individuals with PMD is thought to be lower than in the GP, possibly due to a shorter life expectancy. They have reduced exposure to cancer risk factors, such as alcohol, tobacco, sunlight, human papillomavirus infection, occupational toxins, and being overweight. On the other hand, individuals with PMD present a greater frequency of gastroesophageal reflux disease, Helicobacter pylori gastritis, chronic cystitis, and cryptorchidism, which increase the risk for cancer of the esophagus, stomach, urinary bladder, and testes. In addition, certain genetic disorders underlying compromised motor and cognitive functions are associated with higher risk of childhood cancers. An analysis of 135 cancers in persons with PMD in Japan suggested that they present a particular tumor profile, with certain cancers rarer than in the GP, whereas cancers of the digestive tract are frequent. Cancers of the digestive tract occurred significantly earlier than in the GP (colon: average age 48.3 years vs. 71.3 years in the GP, esophagus: 39 years vs. 72 years in the GP). An increasing number of therapeutic successes in children and adults with PMD have been reported in different countries when cancers are discovered early. Conclusion Individuals with PMD must be appropriately monitored for cancer. Screenings for breast and colon cancer, as well as regular monitoring of the esophagus, stomach, urinary bladder, and testicles, are necessary. Population-based epidemiological studies are needed to better understand risk factors, frequency, and distribution of cancers in the PMD population." @default.
• W4386162745 created "2023-08-26" @default.
• W4386162745 creator A5032151831 @default.
• W4386162745 creator A5055775084 @default.
• W4386162745 creator A5089241882 @default.
• W4386162745 date "2023-08-25" @default.
• W4386162745 modified "2023-10-13" @default.
• W4386162745 title "Assessing cancer in people with profound and multiple disabilities" @default.
• W4386162745 cites W1439783107 @default.
• W4386162745 cites W1464046758 @default.
• W4386162745 cites W1967081236 @default.
• W4386162745 cites W1976276044 @default.
• W4386162745 cites W1983952423 @default.
• W4386162745 cites W1984594430 @default.
• W4386162745 cites W1986369566 @default.
• W4386162745 cites W2025286303 @default.
• W4386162745 cites W2033710925 @default.
• W4386162745 cites W2041435471 @default.
• W4386162745 cites W2041876703 @default.
• W4386162745 cites W2043243750 @default.
• W4386162745 cites W2045245209 @default.
• W4386162745 cites W2047799829 @default.
• W4386162745 cites W2052351843 @default.
• W4386162745 cites W2073446948 @default.
• W4386162745 cites W2077333261 @default.
• W4386162745 cites W2096554864 @default.
• W4386162745 cites W2123885587 @default.
• W4386162745 cites W2124216273 @default.
• W4386162745 cites W2132079310 @default.
• W4386162745 cites W2133243292 @default.
• W4386162745 cites W2145255165 @default.
• W4386162745 cites W2148642372 @default.
• W4386162745 cites W2151948476 @default.
• W4386162745 cites W2158562156 @default.
• W4386162745 cites W2164389166 @default.
• W4386162745 cites W2165130599 @default.
• W4386162745 cites W2171841187 @default.
• W4386162745 cites W2406288456 @default.
• W4386162745 cites W2412028352 @default.
• W4386162745 cites W2429786975 @default.
• W4386162745 cites W2491619612 @default.
• W4386162745 cites W2523591633 @default.
• W4386162745 cites W2608802505 @default.
• W4386162745 cites W2618860238 @default.
• W4386162745 cites W2770240235 @default.
• W4386162745 cites W2794135592 @default.
• W4386162745 cites W2802470474 @default.
• W4386162745 cites W2889457336 @default.
• W4386162745 cites W2896129369 @default.
• W4386162745 cites W2908851662 @default.
• W4386162745 cites W2912121831 @default.
• W4386162745 cites W2913264965 @default.
• W4386162745 cites W2944295449 @default.
• W4386162745 cites W2969977575 @default.
• W4386162745 cites W2979573083 @default.
• W4386162745 cites W2983396130 @default.
• W4386162745 cites W2987523098 @default.
• W4386162745 cites W3009807329 @default.
• W4386162745 cites W3175451829 @default.
• W4386162745 cites W3201133800 @default.
• W4386162745 cites W406585013 @default.
• W4386162745 cites W4307425915 @default.
• W4386162745 doi "https://doi.org/10.1186/s12885-023-11313-3" @default.
• W4386162745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37626285" @default.
• W4386162745 hasPublicationYear "2023" @default.
• W4386162745 type Work @default.
• W4386162745 citedByCount "0" @default.
• W4386162745 crossrefType "journal-article" @default.
• W4386162745 hasAuthorship W4386162745A5032151831 @default.
• W4386162745 hasAuthorship W4386162745A5055775084 @default.
• W4386162745 hasAuthorship W4386162745A5089241882 @default.
• W4386162745 hasBestOaLocation W43861627451 @default.
• W4386162745 hasConcept C121608353 @default.
• W4386162745 hasConcept C126322002 @default.
• W4386162745 hasConcept C143998085 @default.
• W4386162745 hasConcept C2777819096 @default.
• W4386162745 hasConcept C2779134260 @default.
• W4386162745 hasConcept C2908647359 @default.
• W4386162745 hasConcept C71924100 @default.
• W4386162745 hasConcept C99454951 @default.
• W4386162745 hasConceptScore W4386162745C121608353 @default.
• W4386162745 hasConceptScore W4386162745C126322002 @default.
• W4386162745 hasConceptScore W4386162745C143998085 @default.
• W4386162745 hasConceptScore W4386162745C2777819096 @default.
• W4386162745 hasConceptScore W4386162745C2779134260 @default.
• W4386162745 hasConceptScore W4386162745C2908647359 @default.
• W4386162745 hasConceptScore W4386162745C71924100 @default.
• W4386162745 hasConceptScore W4386162745C99454951 @default.
• W4386162745 hasIssue "1" @default.
• W4386162745 hasLocation W43861627451 @default.
• W4386162745 hasLocation W43861627452 @default.
• W4386162745 hasOpenAccess W4386162745 @default.
• W4386162745 hasPrimaryLocation W43861627451 @default.
• W4386162745 hasRelatedWork W1582999690 @default.
• W4386162745 hasRelatedWork W1967395253 @default.
• W4386162745 hasRelatedWork W2014435840 @default.
• W4386162745 hasRelatedWork W2371403176 @default.
• W4386162745 hasRelatedWork W2409125719 @default.
• W4386162745 hasRelatedWork W2415717579 @default.
• W4386162745 hasRelatedWork W2418232956 @default.

• next