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- W4386191639 abstract "A new automated, generic analytical approach for determining the clinical disinfectant o-phthalaldehyde (OPA) is reported in this study. The proposed sequential injection analysis (SIA) is based on the online reaction of the OPA with glycine/N-acetylcysteine (NAC) in a neutral medium (pH = 7.0) to form a highly fluorescent isoindole derivative. All critical flow and reaction variables were investigated, while validation was carried out in the linearity detection range (0.0075-0.02%). As a result, excellent linearity (R2 > 0.99) and precision (1.5-2.4% for repeatability and 0.7-2.2% for reproducibility) were achieved for the reference OPA solutions. Furthermore, reasonable concentration verification of OPA disinfection (0.2-0.6%) in healthcare institutes can be achieved using the developed fluorescent SIA due to its good sensitivity (0.111 V/%) and precision (1.0-2.3% for intermediate precision) around the minimum effective concentration (MEC) of 0.3% for Cidex-OPA disinfectant." @default.
- W4386191639 created "2023-08-27" @default.
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- W4386191639 date "2023-08-26" @default.
- W4386191639 modified "2023-10-18" @default.
- W4386191639 title "Determination of o-phthalaldehyde for dose verification of the clinical disinfectant by fluorescent sequential injection analysis" @default.
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- W4386191639 doi "https://doi.org/10.1007/s44211-023-00415-4" @default.
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