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- W4386201118 abstract "This study aims to identify the risk factors associated with heart failure with preserved ejection fraction (HFpEF) and to investigate the potential correlation between HFpEF and blood lipid metabolism.A retrospective analysis was conducted on a cohort of 47 HFpEF cases (designated as the research group, RG) and 53 non-HF patients (referred to as the control group, CG) admitted to our hospital between December 2020 and December 2022. Clinical baseline data were carefully collected, and lipid profiles were assessed. Logistic regression analysis was used to examine the various factors influencing the onset of HFpEF. Furthermore, we investigated the differences in blood lipid metabolism markers between the two groups and explored the potential relationship between blood lipid metabolism and left ventricular ejection fraction (LVEF) in patients belonging to the RG.The outcomes of the logistic regression analysis revealed that age, sex, sarcopenia, and lipid levels were all independent factors influencing HFpEF (P < .05). Notably, the RG exhibited higher levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C), alongside lower levels of high-density lipoprotein cholesterol (HDL-C), compared to the CG (P < .05). The Pearson correlation coefficients unveiled negative correlations between TG, TC, LDL-C, and LVEF (P < .05), while a positive correlation was observed between HDL-C and LVEF (P < .05).Age, sex, sarcopenia, and lipid levels emerge as independent factors contributing to the onset of HFpEF. Moreover, HFpEF patients manifest apparent irregularities in blood lipid metabolism." @default.
- W4386201118 created "2023-08-28" @default.
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- W4386201118 date "2023-08-25" @default.
- W4386201118 modified "2023-09-24" @default.
- W4386201118 title "Analysis of Risk Factors for Heart Failure with Preserved Ejection Fraction and Observations on Blood Lipid Metabolism." @default.
- W4386201118 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37632969" @default.
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