Matches in SemOpenAlex for { <https://semopenalex.org/work/W4386213858> ?p ?o ?g. }
- W4386213858 endingPage "2000" @default.
- W4386213858 startingPage "1990" @default.
- W4386213858 abstract "Computed tomography angiography (CTA) and invasive coronary angiography (ICA) are routinely performed before transcatheter aortic valve replacement (TAVR) to assess aortic root anatomy and screen for coronary artery disease (CAD), respectively. This study explored the efficacy of CTA as a screening tool for significant proximal CAD before TAVR. With proper ethical oversight, patients undergoing TAVR at Cleveland Clinic with a preprocedural CTA and invasive coronary angiography (ICA), and no prior percutaneous intervention, were identified from 2015 to 2021. Blinded to ICA results, the authors reviewed the left main, proximal left anterior descending coronary artery, proximal left circumflex coronary artery, and proximal right coronary artery by CTA coronary reconstruction to assess for nonsignificant stenosis (0% to 49%), moderate stenosis (50% to 69%), and severe stenosis (≥70%). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and Cohen Kappa statistic were analyzed. 2,217 patients (53.4% male, age 79.2 ± 8.5 years) met inclusion criteria. CTA evaluation revealed a sensitivity of 90%, specificity of 92%, PPV of 74%, and NPV of 97% for detecting ≥50% stenosis. Using a ≥70% stenosis cutoff, evaluation revealed a sensitivity of 91%, specificity of 97%, PPV of 83%, and NPV of 99%. Assessment of bypass graft patency revealed a sensitivity of 86%, specificity of 97%, PPV of 84%, and NPV of 98%. Cohen Kappa analysis indicated substantial to near perfect agreement between pre-TAVR CTA and ICA. Pre-TAVR CTA has a high NPV for high-grade proximal stenosis of each coronary artery. As a result, CTA can be used as a screening tool to rule out significant proximal CAD in patients undergoing TAVR." @default.
- W4386213858 created "2023-08-29" @default.
- W4386213858 creator A5002802676 @default.
- W4386213858 creator A5019666220 @default.
- W4386213858 creator A5033309479 @default.
- W4386213858 creator A5035952992 @default.
- W4386213858 creator A5055406044 @default.
- W4386213858 creator A5063498346 @default.
- W4386213858 creator A5065968450 @default.
- W4386213858 creator A5084358796 @default.
- W4386213858 creator A5086890034 @default.
- W4386213858 creator A5087247030 @default.
- W4386213858 creator A5091516334 @default.
- W4386213858 date "2023-08-01" @default.
- W4386213858 modified "2023-10-02" @default.
- W4386213858 title "Effectiveness of Pre-TAVR CTA as a Screening Tool for Significant CAD Before TAVR" @default.
- W4386213858 cites W1507413178 @default.
- W4386213858 cites W1882986778 @default.
- W4386213858 cites W2042463250 @default.
- W4386213858 cites W2046534269 @default.
- W4386213858 cites W2105716445 @default.
- W4386213858 cites W2125695027 @default.
- W4386213858 cites W2144699697 @default.
- W4386213858 cites W2256381296 @default.
- W4386213858 cites W2516690363 @default.
- W4386213858 cites W2596188051 @default.
- W4386213858 cites W2751630023 @default.
- W4386213858 cites W2883854358 @default.
- W4386213858 cites W2976969014 @default.
- W4386213858 cites W2997889290 @default.
- W4386213858 cites W3115258265 @default.
- W4386213858 cites W3128235271 @default.
- W4386213858 cites W3195842247 @default.
- W4386213858 cites W3199019011 @default.
- W4386213858 cites W3210853063 @default.
- W4386213858 cites W4280617248 @default.
- W4386213858 cites W4288456821 @default.
- W4386213858 doi "https://doi.org/10.1016/j.jcin.2023.05.030" @default.
- W4386213858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37648347" @default.
- W4386213858 hasPublicationYear "2023" @default.
- W4386213858 type Work @default.
- W4386213858 citedByCount "1" @default.
- W4386213858 countsByYear W43862138582023 @default.
- W4386213858 crossrefType "journal-article" @default.
- W4386213858 hasAuthorship W4386213858A5002802676 @default.
- W4386213858 hasAuthorship W4386213858A5019666220 @default.
- W4386213858 hasAuthorship W4386213858A5033309479 @default.
- W4386213858 hasAuthorship W4386213858A5035952992 @default.
- W4386213858 hasAuthorship W4386213858A5055406044 @default.
- W4386213858 hasAuthorship W4386213858A5063498346 @default.
- W4386213858 hasAuthorship W4386213858A5065968450 @default.
- W4386213858 hasAuthorship W4386213858A5084358796 @default.
- W4386213858 hasAuthorship W4386213858A5086890034 @default.
- W4386213858 hasAuthorship W4386213858A5087247030 @default.
- W4386213858 hasAuthorship W4386213858A5091516334 @default.
- W4386213858 hasConcept C126322002 @default.
- W4386213858 hasConcept C126838900 @default.
- W4386213858 hasConcept C164705383 @default.
- W4386213858 hasConcept C197321550 @default.
- W4386213858 hasConcept C2776820930 @default.
- W4386213858 hasConcept C2778088351 @default.
- W4386213858 hasConcept C2778213512 @default.
- W4386213858 hasConcept C2778742706 @default.
- W4386213858 hasConcept C2780007028 @default.
- W4386213858 hasConcept C2780026749 @default.
- W4386213858 hasConcept C2780400711 @default.
- W4386213858 hasConcept C2780643987 @default.
- W4386213858 hasConcept C2781347138 @default.
- W4386213858 hasConcept C3019004856 @default.
- W4386213858 hasConcept C500558357 @default.
- W4386213858 hasConcept C71924100 @default.
- W4386213858 hasConceptScore W4386213858C126322002 @default.
- W4386213858 hasConceptScore W4386213858C126838900 @default.
- W4386213858 hasConceptScore W4386213858C164705383 @default.
- W4386213858 hasConceptScore W4386213858C197321550 @default.
- W4386213858 hasConceptScore W4386213858C2776820930 @default.
- W4386213858 hasConceptScore W4386213858C2778088351 @default.
- W4386213858 hasConceptScore W4386213858C2778213512 @default.
- W4386213858 hasConceptScore W4386213858C2778742706 @default.
- W4386213858 hasConceptScore W4386213858C2780007028 @default.
- W4386213858 hasConceptScore W4386213858C2780026749 @default.
- W4386213858 hasConceptScore W4386213858C2780400711 @default.
- W4386213858 hasConceptScore W4386213858C2780643987 @default.
- W4386213858 hasConceptScore W4386213858C2781347138 @default.
- W4386213858 hasConceptScore W4386213858C3019004856 @default.
- W4386213858 hasConceptScore W4386213858C500558357 @default.
- W4386213858 hasConceptScore W4386213858C71924100 @default.
- W4386213858 hasIssue "16" @default.
- W4386213858 hasLocation W43862138581 @default.
- W4386213858 hasLocation W43862138582 @default.
- W4386213858 hasOpenAccess W4386213858 @default.
- W4386213858 hasPrimaryLocation W43862138581 @default.
- W4386213858 hasRelatedWork W1978150748 @default.
- W4386213858 hasRelatedWork W2024549923 @default.
- W4386213858 hasRelatedWork W2091889534 @default.
- W4386213858 hasRelatedWork W2102985951 @default.
- W4386213858 hasRelatedWork W2110315216 @default.
- W4386213858 hasRelatedWork W2182674358 @default.